Basic domain of telomere guardian TRF2 reduces D-loop unwinding whereas Rap1 restores it.

Necasová I, Janoušková E, Klumpler T, Hofr C
Nucleic Acids Res 45(21):12170-12180 (2017 Dec 1)

PMID: 28981702 doi: 10.1093/nar/gkx812

Submitted to SASBDB: 2017 Jan 6 Published in SASBDB: 2017 Sep 18

SASDC62 – Basic domain of telomeric repeat-binding factor 2 (TRF2) Sample: Basic domain of telomeric repeat-binding factor 2 monomer, 5 kDa Homo sapiens protein Buffer: 50 mM NaPi, 50 mM NaCl, pH: 7 Experiment: SAXS data collected at Rigaku BioSAXS-1000, CEITEC on 2015 Mar 5 RgGuinier 1.7 nm Dmax 7.1 nm VolumePorod 4 nm3

SASDB79 – Basic domain of human telomeric repeat-binding factor 2 (TRF2) in complex with telomeric DNA duplex Sample: Basic domain of telomeric repeat-binding factor 2 monomer, 5 kDa Homo sapiens protein Telomere DNA duplex monomer, 11 kDa DNA Buffer: 20 mM Tris-HCl, 50 mM LiCl, pH: 7.5 Experiment: SAXS data collected at Rigaku BioSAXS-1000, CEITEC on 2016 May 3 RgGuinier 1.7 nm Dmax 6.0 nm VolumePorod 20 nm3

SASDB89 – Telomeric DNA duplex Sample: Telomere DNA duplex monomer, 11 kDa DNA Buffer: 20 mM Tris-HCl, 50 mM LiCl, pH: 7.5 Experiment: SAXS data collected at Rigaku BioSAXS-1000, CEITEC on 2016 May 3 RgGuinier 1.6 nm Dmax 5.7 nm VolumePorod 12 nm3