Optical and Structural Characterization of a Chronic Myeloid Leukemia DNA Biosensor.

Cordeiro M, Otrelo-Cardoso AR, Svergun DI, Konarev PV, Lima JC, Santos-Silva T, Baptista PV
ACS Chem Biol 13(5):1235-1242 (2018 May 18)

PMID: 29562136 doi: 10.1021/acschembio.8b00029

Submitted to SASBDB: 2017 Jun 23 Published in SASBDB: 2018 Apr 3

SASDC95 – Light encoded DNA biosensor: e14A DNA Sample: E14A monomer, 21 kDa DNA Buffer: 154 mM NaCl, pH: 8.3 Experiment: SAXS data collected at BM29, ESRF on 2016 Jun 16 RgGuinier 2.8 nm Dmax 12.5 nm

SASDCA5 – Light encoded DNA biosensor: e14B DNA Sample: E14B monomer, 13 kDa DNA Buffer: 154 mM NaCl, pH: 8.3 Experiment: SAXS data collected at BM29, ESRF on 2016 Jun 16 RgGuinier 1.9 nm Dmax 9.0 nm

SASDCB5 – Light encoded DNA biosensor: e14C DNA Sample: E14C monomer, 5 kDa DNA Buffer: 154 mM NaCl, pH: 8.3 Experiment: SAXS data collected at BM29, ESRF on 2016 Jun 16 RgGuinier 1.3 nm Dmax 5.0 nm

SASDCC5 – Light encoded DNA biosensor: e14AB DNA Sample: E14AB monomer, 93 kDa DNA Buffer: 154 mM NaCl, pH: 8.3 Experiment: SAXS data collected at BM29, ESRF on 2016 Jun 16 RgGuinier 5.4 nm Dmax 24.7 nm

SASDCD5 – Light encoded DNA biosensor: e14ABC DNA Sample: E14ABC monomer, 106 kDa DNA Buffer: 154 mM NaCl, pH: 8.3 Experiment: SAXS data collected at BM29, ESRF on 2016 Jun 16 RgGuinier 4.7 nm Dmax 25.0 nm VolumePorod 152 nm3

SASDCE5 – Light encoded DNA biosensor: e13A DNA Sample: E13A monomer, 17 kDa DNA Buffer: 154 mM NaCl, pH: 8.3 Experiment: SAXS data collected at BM29, ESRF on 2013 Nov 22 RgGuinier 2.3 nm Dmax 8.0 nm VolumePorod 24 nm3

SASDCF5 – Light encoded DNA biosensor: e13B DNA Sample: E13B monomer, 10 kDa DNA Buffer: 154 mM NaCl, pH: 8.3 Experiment: SAXS data collected at BM29, ESRF on 2013 Nov 22 RgGuinier 1.8 nm Dmax 7.0 nm VolumePorod 13 nm3

SASDCG5 – Light encoded DNA biosensor: e13C DNA Sample: E13C monomer, 6 kDa DNA Buffer: 154 mM NaCl, pH: 8.3 Experiment: SAXS data collected at BM29, ESRF on 2013 Nov 22 RgGuinier 1.3 nm Dmax 5.0 nm VolumePorod 8 nm3

SASDCH5 – Light encoded DNA biosensor: e13AB DNA Sample: E13AB monomer, 79 kDa DNA Buffer: 154 mM NaCl, pH: 8.3 Experiment: SAXS data collected at BM29, ESRF on 2013 Nov 22 RgGuinier 4.7 nm Dmax 20.0 nm VolumePorod 103 nm3

SASDCJ5 – Light encoded DNA biosensor: e13ABC DNA Sample: E13ABC monomer, 42 kDa DNA Buffer: 154 mM NaCl, pH: 8.3 Experiment: SAXS data collected at BM29, ESRF on 2013 Nov 22 RgGuinier 3.9 nm Dmax 18.0 nm VolumePorod 59 nm3

SASDCK5 – Light encoded DNA biosensor: e13Ae14Be13C DNA Sample: E13Ae14Be13C monomer, 40 kDa DNA Buffer: 154 mM NaCl, pH: 8.3 Experiment: SAXS data collected at BM29, ESRF on 2016 Jun 16 RgGuinier 3.7 nm Dmax 18.0 nm VolumePorod 65 nm3

SASDCL5 – Light encoded DNA biosensor: e14Ae13Be14C DNA Sample: E14Ae13Be14C monomer, 31 kDa DNA Buffer: 154 mM NaCl, pH: 8.3 Experiment: SAXS data collected at BM29, ESRF on 2016 Jun 16 RgGuinier 3.4 nm Dmax 14.0 nm VolumePorod 42 nm3