Structural model of human dUTPase in complex with a novel proteinaceous inhibitor.

Nyíri K, Mertens HDT, Tihanyi B, Nagy GN, Kőhegyi B, Matejka J, Harris MJ, Szabó JE, Papp-Kádár V, Németh-Pongrácz V, Ozohanics O, Vékey K, Svergun DI, Borysik AJ, Vértessy BG
Sci Rep 8(1):4326 (2018 Mar 12)

PMID: 29531348 doi: 10.1038/s41598-018-22145-8

Submitted to SASBDB: 2017 Aug 10 Published in SASBDB: 2018 Feb 27

SASDC57 – Deoxyuridine 5'-triphosphate nucleotidohydrolase Sample: Deoxyuridine 5'-triphosphate nucleotidohydrolase trimer, 54 kDa Homo sapiens protein Buffer: 50 mM HEPES 300 mM NaCl 5 mM MgCl2, pH: 7.5 Experiment: SAXS data collected at EMBL P12, PETRA III on 2016 Jul 9 RgGuinier 3.0 nm Dmax 10.0 nm VolumePorod 117 nm3

SASDC67 – SaPIbov1 pathogenicity island repressor Sample: SaPIbov1 pathogenicity island repressor dimer, 64 kDa Staphylococcus aureus protein Buffer: 50 mM HEPES 300 mM NaCl 5 mM MgCl2, pH: 7.5 Experiment: SAXS data collected at EMBL P12, PETRA III on 2016 Jul 9 RgGuinier 3.3 nm Dmax 10.5 nm VolumePorod 100 nm3

SASDC77 – Deoxyuridine 5'-triphosphate nucleotidohydrolase complex with SaPIbov1 pathogenicity island repressor [3:3] (SEC-SAXS) Sample: Deoxyuridine 5'-triphosphate nucleotidohydrolase trimer, 54 kDa Homo sapiens protein SaPIbov1 pathogenicity island repressor dimer, 64 kDa Staphylococcus aureus protein Buffer: 50 mM HEPES 300 mM NaCl 5 mM MgCl2, pH: 7.5 Experiment: SAXS data collected at EMBL P12, PETRA III on 2016 Jul 10 RgGuinier 4.4 nm Dmax 17.0 nm VolumePorod 227 nm3

SASDC87 – Deoxyuridine 5'-triphosphate nucleotidohydrolase complex with SaPIbov1 pathogenicity island repressor [3:2] (SEC-SAXS) Sample: Deoxyuridine 5'-triphosphate nucleotidohydrolase trimer, 54 kDa Homo sapiens protein SaPIbov1 pathogenicity island repressor dimer, 64 kDa Staphylococcus aureus protein Buffer: 50 mM HEPES 300 mM NaCl 5 mM MgCl2, pH: 7.5 Experiment: SAXS data collected at EMBL P12, PETRA III on 2016 Jul 10 RgGuinier 3.8 nm Dmax 14.0 nm VolumePorod 190 nm3