The PHD and chromo domains regulate the ATPase activity of the human chromatin remodeler CHD4.

Watson AA, Mahajan P, Mertens HD, Deery MJ, Zhang W, Pham P, Du X, Bartke T, Zhang W, Edlich C, Berridge G, Chen Y, Burgess-Brown NA, Kouzarides T, Wiechens N, Owen-Hughes T, Svergun DI, Gileadi O, Laue ED
J Mol Biol 422(1):3-17 (2012 Sep 7)

PMID: 22575888 doi: 10.1016/j.jmb.2012.04.031

Published in SASBDB: 2015 Jul 7

SASDA85 – CHD4 (PP-CC-AH-D) Sample: Human Chromatin Remodeler CHD4 (363-1353) monomer, 117 kDa Homo sapiens protein Buffer: 50 mM HEPES 5% Glycerol 300 mM NaCl, pH: 7.5 Experiment: SAXS data collected at EMBL X33, DORIS III, DESY on 2010 Nov 13 RgGuinier 4.9 nm Dmax 17.4 nm

SASDA95 – CHD4 (CC-AH-D) Sample: Human Chromatin Remodeler CHD4 (494-1353) monomer, 101 kDa Homo sapiens protein Buffer: 50 mM HEPES 50 mM KCl, pH: 7.5 Experiment: SAXS data collected at EMBL X33, DORIS III, DESY on 2010 Nov 13 RgGuinier 4.0 nm Dmax 14.5 nm

SASDAA5 – CHD4 (AH) Sample: Human Chromatin Remodeler CHD4 (685-1233) monomer, 63 kDa Homo sapiens protein Buffer: 50 mM HEPES 50 mM KCl, pH: 7.5 Experiment: SAXS data collected at EMBL X33, DORIS III, DESY on 2010 Nov 13 RgGuinier 4.0 nm Dmax 14.5 nm

SASDAB5 – CHD4 (PP-CC) Sample: Human Chromatin Remodeler CHD4 (363-682) monomer, 38 kDa Homo sapiens protein Buffer: 50 mM HEPES 50 mM KCl, pH: 7.5 Experiment: SAXS data collected at EMBL X33, DORIS III, DESY on 2010 Nov 13 RgGuinier 3.0 nm Dmax 10.5 nm