An NAD⁺ Phosphorylase Toxin Triggers Mycobacterium tuberculosis Cell Death.

Freire DM, Gutierrez C, Garza-Garcia A, Grabowska AD, Sala AJ, Ariyachaokun K, Panikova T, Beckham KSH, Colom A, Pogenberg V, Cianci M, Tuukkanen A, Boudehen YM, Peixoto A, Botella L, Svergun DI, Schnappinger D, Schneider TR, Genevaux P, de Carvalho LPS, Wilmanns M, Parret AHA, Neyrolles O
Mol Cell (2019 Feb 8)

PMID: 30792174 doi: 10.1016/j.molcel.2019.01.028

Submitted to SASBDB: 2018 Jan 12 Published in SASBDB: 2019 Feb 25

SASDD33 – Toxin/Antitoxin complex from M. tuberculosis Sample: Mycobacterial cidal toxin hexamer, 121 kDa Mycobacterium tuberculosis protein Mycobacterial cidal antitoxin hexamer, 76 kDa Mycobacterium tuberculosis protein Buffer: 100 mM HEPES, 100 mM NaCl, pH: 7.5 Experiment: SAXS data collected at EMBL P12, PETRA III on 2015 Jun 2 RgGuinier 4.1 nm Dmax 11.4 nm VolumePorod 262 nm3