An N-terminally truncated form of cyclic GMP-dependent protein kinase Iα (PKG Iα) is monomeric and autoinhibited and provides a model for activation.

Moon TM, Sheehe JL, Nukareddy P, Nausch LW, Wohlfahrt J, Matthews DE, Blumenthal DK, Dostmann WR
J Biol Chem 293(21):7916-7929 (2018 May 25)
PMID: 29602907
doi: 10.1074/jbc.RA117.000647 		Submitted to SASBDB: 2018 Mar 2
Published in SASBDB:

SASDDS4 – cGMP-dependent protein kinase 1: ∆53 PKG Iα

cGMP-dependent protein kinase 1 experimental SAS data
DAMFILT model
Sample: CGMP-dependent protein kinase 1 monomer, 70 kDa Bos taurus protein
Buffer: 50 mM MES, 300 mM NaCl, 1 mM TCEP, 5 mM DTT, pH: 6.9
Experiment: SAXS data collected at BL4-2, Stanford Synchrotron Radiation Lightsource (SSRL) on 2015 Jun 6
RgGuinier 3.0 nm
Dmax 9.7 nm
VolumePorod 105 nm3