The molecular basis of protein toxin HicA-dependent binding of the protein antitoxin HicB to DNA.

Winter AJ, Williams C, Isupov MN, Crocker H, Gromova M, Marsh P, Wilkinson OJ, Dillingham MS, Harmer NJ, Titball RW, Crump MP
J Biol Chem (2018 Oct 18)

PMID: 30337369 doi: 10.1074/jbc.RA118.005173

Submitted to SASBDB: 2018 Mar 17 Published in SASBDB: 2018 Nov 3

SASDD45 – Type II toxin-antitoxin system HicB family antitoxin - HicB protein Sample: Type II toxin-antitoxin system HicB family antitoxin tetramer, 63 kDa Burkholderia pseudomallei protein Buffer: 25 mM Tris, 150 mM NaCl, pH: 7.5 Experiment: SAXS data collected at B21, Diamond Light Source on 2016 Jul 28 RgGuinier 3.0 nm Dmax 10.5 nm VolumePorod 112 nm3

SASDD55 – Type II toxin-antitoxin system HicB family antitoxin - HicB protein - bound to addiction module toxin, HicA Sample: Type II toxin-antitoxin system HicB family antitoxin tetramer, 63 kDa Burkholderia pseudomallei protein Addiction module toxin, HicA monomer, 7 kDa Burkholderia pseudomallei protein Buffer: 25 mM Tris, 150 mM NaCl, pH: 7.5 Experiment: SAXS data collected at B21, Diamond Light Source on 2016 Jul 27 RgGuinier 3.2 nm Dmax 11.0 nm VolumePorod 110 nm3