The CD27L and CTP1L endolysins targeting Clostridia contain a built-in trigger and release factor.
Dunne M,
Mertens HD,
Garefalaki V,
Jeffries CM,
Thompson A,
Lemke EA,
Svergun DI,
Mayer MJ,
Narbad A,
Meijers R
PLoS Pathog
10(7):e1004228
(2014 Jul)
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Sample: |
Clostridium difficile bacteriophage 27 endolysin dimer, 64 kDa Clostridioides difficile protein
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Buffer: |
20 mM HEPES 150 mM NaCl, pH: 7.5 |
Experiment: |
SAXS
data collected at EMBL X33, DORIS III, DESY on 2011 Mar 17
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RgGuinier |
3.3 |
nm |
Dmax |
10.6 |
nm |
VolumePorod |
72 |
nm3 |
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Sample: |
Clostridium difficile bacteriophage 27 endolysin C238R mutant dimer, 64 kDa Clostridioides difficile protein
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Buffer: |
20 mM HEPES 500 mM NaCl, pH: 7.5 |
Experiment: |
SAXS
data collected at EMBL P12, PETRA III on 2013 Jun 21
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RgGuinier |
4.2 |
nm |
Dmax |
14.7 |
nm |
VolumePorod |
92 |
nm3 |
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