Molecular mechanism for the action of the anti-CD44 monoclonal antibody MEM-85.

Škerlová J, Král V, Kachala M, Fábry M, Bumba L, Svergun DI, Tošner Z, Veverka V, Řezáčová P
J Struct Biol 191(2):214-23 (2015 Aug)
PMID: 26066970
doi: 10.1016/j.jsb.2015.06.005 		Published in SASBDB:

SASDAG7 – CD44 HABD scFv MEM-85 complex

Hyaluronate binding domain of CD44 antigenSingle-chain Variable Fragment of Antibody MEM-85 experimental SAS data
DAMMIN model
Sample: Hyaluronate binding domain of CD44 antigen monomer, 18 kDa Homo sapiens protein
Single-chain Variable Fragment of Antibody MEM-85 monomer, 29 kDa Mus musculus protein
Buffer: PBS, pH: 7.4
Experiment: SAXS data collected at EMBL P12, PETRA III on 2013 Oct 31
RgGuinier 2.7 nm
Dmax 9.4 nm
VolumePorod 57 nm3