Dimerization-Induced Allosteric Changes of the Oxyanion-Hole Loop Activate the Pseudorabies Virus Assemblin pUL26N, a Herpesvirus Serine Protease.
Zühlsdorf M,
Werten S,
Klupp BG,
Palm GJ,
Mettenleiter TC,
Hinrichs W
PLoS Pathog
11(7):e1005045
(2015 Jul)
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Sample: |
VP24 dimer, 53 kDa Suid herpesvirus 1 protein
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Buffer: |
50 mM Tris/HCl 0.5 M NaCl 0.25 M imidazole 5% glycerol 50 mM urea 0.2 M MgCl2, pH: 7.5 |
Experiment: |
SAXS
data collected at EMBL P12, PETRA III on 2013 Sep 23
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RgGuinier |
2.6 |
nm |
Dmax |
10.6 |
nm |
VolumePorod |
73 |
nm3 |
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