Structural insights into conformational switching in latency-associated peptide between transforming growth factor β-1 bound and unbound states

Stachowski T, Snell M, Snell E
IUCrJ 7(2) (2020 Feb 06)

doi: 10.1107/S205225251901707X 		Submitted to SASBDB: 2019 Sep 4
Published in SASBDB:

SASDG55 – Deglycosylated latency associated peptide, LAP (TGFB-1)

Latency associated peptide experimental SAS data
Latency associated peptide Kratky plot
Sample: Latency associated peptide dimer, 58 kDa Homo sapiens protein
Buffer: phosphate buffered saline 2% glycerol, pH: 7.4
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2019 Apr 20
RgGuinier 3.5 nm
Dmax 13.0 nm
VolumePorod 129 nm3