Large-scale conformational rearrangement of the α5-helix of Gα subunits in complex with the guanine nucleotide exchange factor Ric8A.

Srivastava D, Artemyev NO
J Biol Chem (2019 Oct 17)
PMID: 31624147
doi: 10.1074/jbc.AC119.011135 		Submitted to SASBDB: 2019 Sep 26
Published in SASBDB:

SASDGB6 – Resistance to inhibitors of cholinesterase 8 homolog A (Ric8A) miniGi complex

Resistance to inhibitors of cholinesterase 8 homolog AminiGi experimental SAS data
OTHER model
Sample: Resistance to inhibitors of cholinesterase 8 homolog A monomer, 56 kDa Bos taurus protein
MiniGi monomer, 25 kDa synthetic construct protein
Buffer: 20 mM Tris, 150 mM KCl, 5 % glycerol, 1 mM TCEP, pH: 8
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2018 Oct 27
RgGuinier 3.2 nm
Dmax 10.7 nm