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2 hits found for Horikoshi

SASDJ35 – Glucose-6-phosphate dehydrogenase dimer

Glucose-6-phosphate 1-dehydrogenase experimental SAS data
PYMOL model
Sample: Glucose-6-phosphate 1-dehydrogenase dimer, 119 kDa Homo sapiens protein
Buffer: 20 mM Tris, 150 mM NaCl, pH: 8
Experiment: SAXS data collected at BL4-2, Stanford Synchrotron Radiation Lightsource (SSRL) on 2019 Jul 24
Long-range structural defects by pathogenic mutations in most severe glucose-6-phosphate dehydrogenase deficiency Proceedings of the National Academy of Sciences 118(4) (2021)
Horikoshi N, Hwang S, Gati C, Matsui T, Castillo-Orellana C, Raub A, Garcia A, Jabbarpour F, Batyuk A, Broweleit J, Xiang X, Chiang A, Broweleit R, Vöhringer-Martinez E, Mochly-Rosen D, Wakatsuki S
RgGuinier 3.6 nm
Dmax 12.1 nm
VolumePorod 160 nm3

SASDJ45 – Glucose-6-phosphate dehydrogenase P396L mutant

Glucose-6-phosphate 1-dehydrogenase P396L experimental SAS data
CORAL model
Sample: Glucose-6-phosphate 1-dehydrogenase P396L dimer, 119 kDa Homo sapiens protein
Buffer: 20 mM Tris, 150 mM NaCl, pH: 8
Experiment: SAXS data collected at BL4-2, Stanford Synchrotron Radiation Lightsource (SSRL) on 2019 Jul 24
Long-range structural defects by pathogenic mutations in most severe glucose-6-phosphate dehydrogenase deficiency Proceedings of the National Academy of Sciences 118(4) (2021)
Horikoshi N, Hwang S, Gati C, Matsui T, Castillo-Orellana C, Raub A, Garcia A, Jabbarpour F, Batyuk A, Broweleit J, Xiang X, Chiang A, Broweleit R, Vöhringer-Martinez E, Mochly-Rosen D, Wakatsuki S
RgGuinier 3.7 nm
Dmax 13.0 nm
VolumePorod 178 nm3