Synchrotron SAXS data from solutions of HIV-1 Envelope Glycoprotein SOSIP from a transmitted founder virus of the CH505 isolate including 4.1 stabilization mutations in 15 mM HEPES, 150 mM NaCl, pH 7.1 were collected on the 12.3.1 (SIBYLS) beam line at the Advanced Light Source (ALS; Berkeley, CA, USA) using a MAR 165 CCD detector at a wavelength of λ = 0.1 nm (I(s) vs s, where s = 4πsinθ/λ, and 2θ is the scattering angle). One solute concentration of 3.00 mg/ml was measured at 25°C for a total exposure time of 10 s. The data were normalized to the intensity of the transmitted beam and radially averaged; the scattering of the solvent-blank was subtracted.
Data reduction was performed in the SIBYLS Beamline reduction software. Data analysis was performed using the ATSAS package.