2 hits found for Human immunoglobulin gamma 1 (IgG1) SAP1.3 - heavy chain

SASDWV2 – Human immunoglobulin gamma 1 (IgG1) SAP1.3 Sample: Human immunoglobulin gamma 1 (IgG1) SAP1.3 - heavy chain dimer, 99 kDa Homo sapiens protein Human immunoglobulin SAP1.3 - kappa chain dimer, 48 kDa Homo sapiens protein Buffer: ...150 mM KCl, pH: 7.5 Experiment: SAXS data collected at BM29, ESRF on 2024 Sep 28 Structure-guided disulfide engineering restricts antibody conformation to elicit TNFR agonism. Nat Commun 16(1):3495 (2025) Elliott IG, Fisher H, Chan HTC, Inzhelevskaya T, Mockridge CI, Penfold CA, Duriez PJ, Orr CM, Herniman J, Müller KTJ, Essex JW, Cragg MS, Tews I RgGuinier 5.2 nm Dmax 16.8 nm VolumePorod 229 nm3

SASDUF8 – Human immunoglobulin gamma 1 (IgG1) SAP1.3 F(ab')2 Sample: Human immunoglobulin gamma 1 (IgG1) SAP1.3 F(ab')2 - heavy chain dimer, 51 kDa Homo sapiens protein Human immunoglobulin gamma 1 (IgG1) SAP1.3 F(ab')2 - kappa light chain dimer, 48 kDa Homo sapiens protein Buffer: ...150 mM KCl, pH: 7.5 Experiment: SAXS data collected at BM29, ESRF on 2022 Jun 8 Structure-guided disulfide engineering restricts antibody conformation to elicit TNFR agonism. Nat Commun 16(1):3495 (2025) Elliott IG, Fisher H, Chan HTC, Inzhelevskaya T, Mockridge CI, Penfold CA, Duriez PJ, Orr CM, Herniman J, Müller KTJ, Essex JW, Cragg MS, Tews I RgGuinier 4.5 nm Dmax 16.3 nm VolumePorod 139 nm3