Coat Protein-Dependent Behavior of Poly(ethylene glycol) Tails in Iron Oxide Core Virus-like Nanoparticles.

Malyutin AG, Cheng H, Sanchez-Felix OR, Carlson K, Stein BD, Konarev PV, Svergun DI, Dragnea B, Bronstein LM, ACS Appl Mater Interfaces 7(22):12089-98 (2015) Europe PMC

SASDMZ8 – Iron oxide nanoparticles (NP-P3) (60% of 5 kDa PEG tails)

Iron oxide nanoparticles (NP-P3) (60% of 5 kDa PEG tails)
MWexperimental 800 kDa
MWexpected 5000 kDa
log I(s) 7.79×103 7.79×102 7.79×101 7.79×100
Iron oxide nanoparticles (NP-P3) (60% of 5 kDa PEG tails) small angle scattering data  s, nm-1
(sRg)2I(s)/I(0)
Iron oxide nanoparticles (NP-P3) (60% of 5 kDa PEG tails) Kratky plot 1.104 0 √3 sRg
p(r)
Iron oxide nanoparticles (NP-P3) (60% of 5 kDa PEG tails) pair distance distribution function Rg: 9.6 nm 0 Dmax: 26 nm

Data validation

Fits and models

log I(s)
 s, nm-1
Iron oxide nanoparticles (NP-P3) (60% of 5 kDa PEG tails) OTHER [STATIC IMAGE] model
Synchrotron SAXS data from solutions of Iron oxide nanoparticles (NP-P3) (60% of 5 kDa PEG tails) in 50 mM Tris-HCl, 50 mM NaCl, 10 mM KCl, 5 mM MgCl2, pH 4.5 were collected on the EMBL X33 beam line at DORIS III (DESY, Hamburg, Germany) using a Pilatus 1M-W detector at a sample-detector distance of 2.9 m and at a wavelength of λ = 0.15 nm (I(s) vs s, where s = 4πsinθ/λ, and 2θ is the scattering angle). One solute concentration of 0.47 mg/ml was measured at 10°C. 10 successive 15 second frames were collected. The data were normalized to the intensity of the transmitted beam and radially averaged; the scattering of the solvent-blank was subtracted.

The data have been scaled for display purposes (original data available in the entry archive.)

Tags: X33
Iron oxide nanoparticles (NP-P3) (60% of 5 kDa PEG tails) (NP-P3)
Mol. type   Other
Olig. state   0
Mon. MW   200 kDa
Chemical formula