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3 hits found for Monoclonal Antibody Fragment

SASDHF4 – ...monoclonal antibody (5D2) complex

Lipoprotein lipaseGlycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1Monoclonal Antibody Fragment 5D2 experimental SAS data
CORAL model
Sample: Lipoprotein lipase monomer, 50 kDa Homo sapiens protein
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 monomer, 15 kDa Homo sapiens protein
Monoclonal Antibody Fragment 5D2 monomer, 47 kDa Mus musculus protein
Buffer: 10 mM Tris, 150 mM NaCl, 4 mM CaCL2, 10% (v/v) Glycerol, 0.05% 0.8mM CHAPS, ,0.05 % (v/v) NaN3, pH: 7.2
Experiment: SAXS data collected at EMBL P12, PETRA III on 2018 Dec 14
Unfolding of monomeric lipoprotein lipase by ANGPTL4: Insight into the regulation of plasma triglyceride metabolism Proceedings of the National Academy of Sciences :201920202 (2020)
Kristensen K, Leth-Espensen K, Mertens H, Birrane G, Meiyappan M, Olivecrona G, Jørgensen T, Young S, Ploug M
RgGuinier 4.9 nm
Dmax 17.5 nm
VolumePorod 187 nm3

SASDKK4 – A-type ATP synthase

n-Dodecyl-β-D-MaltopyranosideA-type ATP synthaseMonoclonal Antibody Fragment experimental SAS data
OTHER model
Sample: n-Dodecyl-β-D-Maltopyranoside , 77 kDa synthetic construct
A-type ATP synthase monomer, 655 kDa Thermus thermophilus protein
Monoclonal Antibody Fragment dimer, 33 kDa Homo sapiens protein
Buffer: 20 mM Tris/HCl, 100 mM sucrose, 100 mM NaCl, 2 mM MgCl2, 10% glycerol, 0.05% b-DDM, pH: 8
Experiment: SAXS data collected at SAXS/WAXS, Australian Synchrotron on 2013 Mar 3
MPBuilder: A PyMOL Plugin for Building and Refinement of Solubilized Membrane Proteins Against Small Angle X-ray Scattering Data Journal of Molecular Biology :166888 (2021)
Molodenskiy D, Svergun D, Mertens H
RgGuinier 8.0 nm
Dmax 27.0 nm
VolumePorod 1549 nm3

SASDM97 – ...monoclonal anti-proNGF antibody in single chain Fv fragment (scFv)

Recombinant monoclonal anti-proNGF antibody in single chain Fv fragment (scFv) experimental SAS data
BUNCH model
Sample: ...monoclonal anti-proNGF antibody in single chain Fv fragment (scFv) monomer, 29 kDa protein
Buffer: phosphate buffered saline, pH: 7
Experiment: SAXS data collected at EMBL X33, DORIS III, DESY on 2005 Oct 21
...antibody fragment. Arch Biochem Biophys 522(1):26-36 (2012)
Paoletti F, Malerba F, Konarev PV, Visintin M, Scardigli R, Fasulo L, Lamba D, Svergun DI, Cattaneo A
RgGuinier 2.7 nm
Dmax 8.0 nm
VolumePorod 39 nm3