Small Angle Scattering Biological Data Bank SASBDB


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48 hits found for Protein-glutamine gamma-glutamyltransferase 2

SASDRE3 – Tissue Transglutaminase + Ca: Time-resolved 0ms

Protein-glutamine gamma-glutamyltransferase 2 experimental SAS data

Protein-glutamine gamma-glutamyltransferase 2 Kratky plot

Sample:	Protein-glutamine gamma-glutamyltransferase 2 , 77 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 100 mM NaCl, 10% glycerol, 1 mM DTT, pH: 7.5
Experiment:	SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2021 Nov 19

Chaotic advection mixer for capturing transient states of diverse biological macromolecular systems with time-resolved small-angle X-ray scattering IUCrJ 10(3):363-375 (2023)
Zielinski K, Katz A, Calvey G, Pabit S, Milano S, Aplin C, San Emeterio J, Cerione R, Pollack L

R_g^Guinier	4.1	nm
D_max	16.0	nm
Volume^Porod	150	nm³

SASDRF3 – ...2 ms

Sample:	Protein-glutamine gamma-glutamyltransferase 2 , 77 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 100 mM NaCl, 10% glycerol, 1 mM DTT, pH: 7.5
Experiment:	SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2021 Nov 19

R_g^Guinier	4.1	nm
D_max	17.0	nm
Volume^Porod	170	nm³

SASDRG3 – Tissue Transglutaminase + Ca: Time-resolved 63 ms

Sample:	Protein-glutamine gamma-glutamyltransferase 2 , 77 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 100 mM NaCl, 10% glycerol, 1 mM DTT, pH: 7.5
Experiment:	SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2021 Nov 19

R_g^Guinier	4.1	nm
D_max	18.0	nm
Volume^Porod	155	nm³

SASDRH3 – Tissue Transglutaminase + Ca: Time-resolved 100 ms

Sample:	Protein-glutamine gamma-glutamyltransferase 2 , 77 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 100 mM NaCl, 10% glycerol, 1 mM DTT, pH: 7.5
Experiment:	SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2021 Nov 19

R_g^Guinier	4.1	nm
D_max	20.0	nm
Volume^Porod	190	nm³

SASDRJ3 – Tissue Transglutaminase + Ca: Time-resolved 316 ms

Sample:	Protein-glutamine gamma-glutamyltransferase 2 , 77 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 100 mM NaCl, 10% glycerol, 1 mM DTT, pH: 7.5
Experiment:	SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2021 Nov 19

R_g^Guinier	4.5	nm
D_max	24.0	nm
Volume^Porod	200	nm³

SASDRK3 – Tissue Transglutaminase + Ca: Time-resolved 631 ms

Sample:	Protein-glutamine gamma-glutamyltransferase 2 , 77 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 100 mM NaCl, 10% glycerol, 1 mM DTT, pH: 7.5
Experiment:	SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2021 Nov 19

R_g^Guinier	4.6	nm
D_max	26.0	nm
Volume^Porod	215	nm³

SASDRL3 – Tissue Transglutaminase + Ca: Time-resolved 1500 ms

Sample:	Protein-glutamine gamma-glutamyltransferase 2 , 77 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 100 mM NaCl, 10% glycerol, 1 mM DTT, pH: 7.5
Experiment:	SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2021 Nov 19

R_g^Guinier	4.6	nm
D_max	28.0	nm
Volume^Porod	230	nm³

SASDTL3 – Tissue Transglutaminase: Equilibrium

Sample:	Protein-glutamine gamma-glutamyltransferase 2 , 77 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 100 mM NaCl, 10% glycerol, 1 mM DTT, pH: 7.5
Experiment:	SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2022 Nov 17

...2 to promote cancer cell survival versus cell death. Commun Biol 7(1):982 (2024)
Aplin C, Zielinski KA, Pabit S, Ogunribido D, Katt WP, Pollack L, Cerione RA, Milano SK

R_g^Guinier	4.2	nm
D_max	20.0	nm
Volume^Porod	148	nm³

SASDRM3 – Tissue Transglutaminase + Ca: 5min Equilibrium

Sample:	Protein-glutamine gamma-glutamyltransferase 2 , 77 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 100 mM NaCl, 10% glycerol, 1 mM DTT, pH: 7.5
Experiment:	SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2021 Sep 29

R_g^Guinier	5.0	nm
D_max	27.0	nm
Volume^Porod	241	nm³

SASDTM3 – ...25 µM GTP

Sample:	Protein-glutamine gamma-glutamyltransferase 2 , 77 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 100 mM NaCl, 10% glycerol, 1 mM DTT, pH: 7.5
Experiment:	SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2022 Nov 17

...2 to promote cancer cell survival versus cell death. Commun Biol 7(1):982 (2024)
Aplin C, Zielinski KA, Pabit S, Ogunribido D, Katt WP, Pollack L, Cerione RA, Milano SK

R_g^Guinier	3.8	nm
D_max	17.5	nm
Volume^Porod	132	nm³

SASDRN3 – Tissue Transglutaminase + Ca: 10min Equilibrium

Sample:	Protein-glutamine gamma-glutamyltransferase 2 , 77 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 100 mM NaCl, 10% glycerol, 1 mM DTT, pH: 7.5
Experiment:	SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2021 Nov 19

R_g^Guinier	5.5	nm
D_max	26.0	nm
Volume^Porod	300	nm³

SASDTN3 – Tissue Transglutaminase + 50 µM GTP

Sample:	Protein-glutamine gamma-glutamyltransferase 2 , 77 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 100 mM NaCl, 10% glycerol, 1 mM DTT, pH: 7.5
Experiment:	SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2022 Nov 17

...2 to promote cancer cell survival versus cell death. Commun Biol 7(1):982 (2024)
Aplin C, Zielinski KA, Pabit S, Ogunribido D, Katt WP, Pollack L, Cerione RA, Milano SK

R_g^Guinier	3.7	nm
D_max	17.5	nm
Volume^Porod	124	nm³

SASDRP3 – Tissue Transglutaminase + Ca: 30min Equilibrium

Sample:	Protein-glutamine gamma-glutamyltransferase 2 , 77 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 100 mM NaCl, 10% glycerol, 1 mM DTT, pH: 7.5
Experiment:	SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2021 Sep 29

R_g^Guinier	6.9	nm
D_max	31.5	nm
Volume^Porod	490	nm³

SASDTP3 – Tissue Transglutaminase + 100 µM GTP

Sample:	Protein-glutamine gamma-glutamyltransferase 2 , 77 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 100 mM NaCl, 10% glycerol, 1 mM DTT, pH: 7.5
Experiment:	SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2022 Nov 17

...2 to promote cancer cell survival versus cell death. Commun Biol 7(1):982 (2024)
Aplin C, Zielinski KA, Pabit S, Ogunribido D, Katt WP, Pollack L, Cerione RA, Milano SK

R_g^Guinier	3.6	nm
D_max	18.0	nm
Volume^Porod	121	nm³

SASDTQ3 – ...250 µM GTP

Sample:	Protein-glutamine gamma-glutamyltransferase 2 , 77 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 100 mM NaCl, 10% glycerol, 1 mM DTT, pH: 7.5
Experiment:	SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2022 Nov 17

...2 to promote cancer cell survival versus cell death. Commun Biol 7(1):982 (2024)
Aplin C, Zielinski KA, Pabit S, Ogunribido D, Katt WP, Pollack L, Cerione RA, Milano SK

R_g^Guinier	3.5	nm
D_max	17.5	nm
Volume^Porod	120	nm³

SASDTR3 – Tissue Transglutaminase + 500 µM GTP

Sample:	Protein-glutamine gamma-glutamyltransferase 2 , 77 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 100 mM NaCl, 10% glycerol, 1 mM DTT, pH: 7.5
Experiment:	SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2022 Nov 17

...2 to promote cancer cell survival versus cell death. Commun Biol 7(1):982 (2024)
Aplin C, Zielinski KA, Pabit S, Ogunribido D, Katt WP, Pollack L, Cerione RA, Milano SK

R_g^Guinier	3.4	nm
D_max	18.0	nm
Volume^Porod	118	nm³

SASDTS3 – Tissue Transglutaminase + 1 mM GTP

Sample:	Protein-glutamine gamma-glutamyltransferase 2 , 77 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 100 mM NaCl, 10% glycerol, 1 mM DTT, pH: 7.5
Experiment:	SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2022 Nov 17

...2 to promote cancer cell survival versus cell death. Commun Biol 7(1):982 (2024)
Aplin C, Zielinski KA, Pabit S, Ogunribido D, Katt WP, Pollack L, Cerione RA, Milano SK

R_g^Guinier	3.4	nm
D_max	17.0	nm
Volume^Porod	115	nm³

SASDTT3 – ...2 mM GTP

Sample:	Protein-glutamine gamma-glutamyltransferase 2 , 77 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 100 mM NaCl, 10% glycerol, 1 mM DTT, pH: 7.5
Experiment:	SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2022 Nov 17

...2 to promote cancer cell survival versus cell death. Commun Biol 7(1):982 (2024)
Aplin C, Zielinski KA, Pabit S, Ogunribido D, Katt WP, Pollack L, Cerione RA, Milano SK

R_g^Guinier	3.3	nm
D_max	17.0	nm
Volume^Porod	111	nm³

SASDTU3 – Tissue Transglutaminase + 5 mM GTP: Equilibrium

Sample:	Protein-glutamine gamma-glutamyltransferase 2 , 77 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 100 mM NaCl, 10% glycerol, 1 mM DTT, 5 mM GTP, pH: 7.5
Experiment:	SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2022 Nov 17

...2 to promote cancer cell survival versus cell death. Commun Biol 7(1):982 (2024)
Aplin C, Zielinski KA, Pabit S, Ogunribido D, Katt WP, Pollack L, Cerione RA, Milano SK

R_g^Guinier	3.2	nm
D_max	14.0	nm
Volume^Porod	108	nm³

SASDTV3 – Tissue Transglutaminase + 5 mM GDP

Sample:	Protein-glutamine gamma-glutamyltransferase 2 , 77 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 100 mM NaCl, 10% glycerol, 1 mM DTT, pH: 7.5
Experiment:	SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2022 Nov 17

...2 to promote cancer cell survival versus cell death. Commun Biol 7(1):982 (2024)
Aplin C, Zielinski KA, Pabit S, Ogunribido D, Katt WP, Pollack L, Cerione RA, Milano SK

R_g^Guinier	3.5	nm
D_max	17.5	nm
Volume^Porod	120	nm³

SASDTW3 – ...250 µM CaCl2

Sample:	Protein-glutamine gamma-glutamyltransferase 2 , 77 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 100 mM NaCl, 10% glycerol, 1 mM DTT, pH: 7.5
Experiment:	SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2022 Nov 17

...2 to promote cancer cell survival versus cell death. Commun Biol 7(1):982 (2024)
Aplin C, Zielinski KA, Pabit S, Ogunribido D, Katt WP, Pollack L, Cerione RA, Milano SK

R_g^Guinier	4.3	nm
D_max	21.0	nm
Volume^Porod	160	nm³

SASDTX3 – ...2

Sample:	Protein-glutamine gamma-glutamyltransferase 2 , 77 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 100 mM NaCl, 10% glycerol, 1 mM DTT, pH: 7.5
Experiment:	SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2022 Nov 17

...2 to promote cancer cell survival versus cell death. Commun Biol 7(1):982 (2024)
Aplin C, Zielinski KA, Pabit S, Ogunribido D, Katt WP, Pollack L, Cerione RA, Milano SK

R_g^Guinier	4.3	nm
D_max	20.0	nm
Volume^Porod	158	nm³

SASDTY3 – ...2

Sample:	Protein-glutamine gamma-glutamyltransferase 2 , 77 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 100 mM NaCl, 10% glycerol, 1 mM DTT, pH: 7.5
Experiment:	SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2022 Nov 17

...2 to promote cancer cell survival versus cell death. Commun Biol 7(1):982 (2024)
Aplin C, Zielinski KA, Pabit S, Ogunribido D, Katt WP, Pollack L, Cerione RA, Milano SK

R_g^Guinier	4.5	nm
D_max	24.0	nm
Volume^Porod	180	nm³

SASDTZ3 – ...2 mM CaCl2

Sample:	Protein-glutamine gamma-glutamyltransferase 2 , 77 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 100 mM NaCl, 10% glycerol, 1 mM DTT, pH: 7.5
Experiment:	SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2022 Nov 17

...2 to promote cancer cell survival versus cell death. Commun Biol 7(1):982 (2024)
Aplin C, Zielinski KA, Pabit S, Ogunribido D, Katt WP, Pollack L, Cerione RA, Milano SK

R_g^Guinier	5.3	nm
D_max	25.5	nm
Volume^Porod	234	nm³

...24 – Tissue Transglutaminase + 50 µM inhibitor LM11

Sample:	Protein-glutamine gamma-glutamyltransferase 2 , 77 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 100 mM NaCl, 10% glycerol, 1 mM DTT, pH: 7.5
Experiment:	SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2022 Nov 17

...2 to promote cancer cell survival versus cell death. Commun Biol 7(1):982 (2024)
Aplin C, Zielinski KA, Pabit S, Ogunribido D, Katt WP, Pollack L, Cerione RA, Milano SK

R_g^Guinier	4.3	nm
D_max	20.0	nm
Volume^Porod	158	nm³

SASDT34 – ...250 µM CaCl2

Sample:	Protein-glutamine gamma-glutamyltransferase 2 , 77 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 100 mM NaCl, 10% glycerol, 1 mM DTT, pH: 7.5
Experiment:	SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2022 Nov 17

...2 to promote cancer cell survival versus cell death. Commun Biol 7(1):982 (2024)
Aplin C, Zielinski KA, Pabit S, Ogunribido D, Katt WP, Pollack L, Cerione RA, Milano SK

R_g^Guinier	4.2	nm
D_max	19.0	nm
Volume^Porod	155	nm³

SASDT44 – ...2

Sample:	Protein-glutamine gamma-glutamyltransferase 2 , 77 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 100 mM NaCl, 10% glycerol, 1 mM DTT, pH: 7.5
Experiment:	SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2022 Nov 17

...2 to promote cancer cell survival versus cell death. Commun Biol 7(1):982 (2024)
Aplin C, Zielinski KA, Pabit S, Ogunribido D, Katt WP, Pollack L, Cerione RA, Milano SK

R_g^Guinier	4.9	nm
D_max	25.0	nm
Volume^Porod	191	nm³

SASDT54 – ...2

Sample:	Protein-glutamine gamma-glutamyltransferase 2 , 77 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 100 mM NaCl, 10% glycerol, 1 mM DTT, pH: 7.5
Experiment:	SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2022 Nov 17

...2 to promote cancer cell survival versus cell death. Commun Biol 7(1):982 (2024)
Aplin C, Zielinski KA, Pabit S, Ogunribido D, Katt WP, Pollack L, Cerione RA, Milano SK

R_g^Guinier	4.7	nm
D_max	28.0	nm
Volume^Porod	198	nm³

SASDT64 – ...2 mM CaCl2

Sample:	Protein-glutamine gamma-glutamyltransferase 2 , 77 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 100 mM NaCl, 10% glycerol, 1 mM DTT, pH: 7.5
Experiment:	SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2022 Nov 17

...2 to promote cancer cell survival versus cell death. Commun Biol 7(1):982 (2024)
Aplin C, Zielinski KA, Pabit S, Ogunribido D, Katt WP, Pollack L, Cerione RA, Milano SK

R_g^Guinier	5.2	nm
D_max	25.0	nm
Volume^Porod	236	nm³

SASDT74 – ...2 + inhibitor LM11: Equilibrium

Sample:	Protein-glutamine gamma-glutamyltransferase 2 , 77 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 100 mM NaCl, 10% glycerol, 1 mM DTT, 2 mM CaCl2, 50 µM LM11, pH: 7.5
Experiment:	SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2022 Nov 17

...2 to promote cancer cell survival versus cell death. Commun Biol 7(1):982 (2024)
Aplin C, Zielinski KA, Pabit S, Ogunribido D, Katt WP, Pollack L, Cerione RA, Milano SK

R_g^Guinier	6.0	nm
D_max	36.0	nm
Volume^Porod	431	nm³

SASDT84 – ...2: Time-resolved 100 ms

Sample:	Protein-glutamine gamma-glutamyltransferase 2 , 77 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 100 mM NaCl, 10% glycerol, 1 mM DTT, pH: 7.5
Experiment:	SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2022 Nov 17

...2 to promote cancer cell survival versus cell death. Commun Biol 7(1):982 (2024)
Aplin C, Zielinski KA, Pabit S, Ogunribido D, Katt WP, Pollack L, Cerione RA, Milano SK

R_g^Guinier	4.6	nm
D_max	32.0	nm
Volume^Porod	242	nm³

SASDT94 – ...2: Time-resolved 316 ms

Sample:	Protein-glutamine gamma-glutamyltransferase 2 , 77 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 100 mM NaCl, 10% glycerol, 1 mM DTT, pH: 7.5
Experiment:	SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2022 Nov 17

...2 to promote cancer cell survival versus cell death. Commun Biol 7(1):982 (2024)
Aplin C, Zielinski KA, Pabit S, Ogunribido D, Katt WP, Pollack L, Cerione RA, Milano SK

R_g^Guinier	4.8	nm
D_max	25.0	nm
Volume^Porod	203	nm³

SASDTA4 – ...2: Time-resolved 631 ms

Sample:	Protein-glutamine gamma-glutamyltransferase 2 , 77 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 100 mM NaCl, 10% glycerol, 1 mM DTT, pH: 7.5
Experiment:	SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2022 Nov 17

...2 to promote cancer cell survival versus cell death. Commun Biol 7(1):982 (2024)
Aplin C, Zielinski KA, Pabit S, Ogunribido D, Katt WP, Pollack L, Cerione RA, Milano SK

R_g^Guinier	5.7	nm
D_max	33.0	nm
Volume^Porod	305	nm³

SASDTB4 – ...2 + inhibitor LM11 + GTP: Equilibrium

Sample:	Protein-glutamine gamma-glutamyltransferase 2 , 77 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 100 mM NaCl, 10% glycerol, 1 mM DTT, 2 mM CaCl2, 50 µM LM11, 5 mM GTP, pH: 7.5
Experiment:	SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2022 Nov 17

...2 to promote cancer cell survival versus cell death. Commun Biol 7(1):982 (2024)
Aplin C, Zielinski KA, Pabit S, Ogunribido D, Katt WP, Pollack L, Cerione RA, Milano SK

R_g^Guinier	6.2	nm
D_max	33.0	nm
Volume^Porod	277	nm³

SASDTC4 – ...26 (1% DMSO)

Sample:	Protein-glutamine gamma-glutamyltransferase 2 , 77 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 100 mM NaCl, 10% glycerol, 1 mM DTT, pH: 7.5
Experiment:	SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2022 Nov 17

...2 to promote cancer cell survival versus cell death. Commun Biol 7(1):982 (2024)
Aplin C, Zielinski KA, Pabit S, Ogunribido D, Katt WP, Pollack L, Cerione RA, Milano SK

R_g^Guinier	4.1	nm
D_max	19.0	nm
Volume^Porod	144	nm³

SASDTD4 – ...26 (2% DMSO)

Sample:	Protein-glutamine gamma-glutamyltransferase 2 , 77 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 100 mM NaCl, 10% glycerol, 1 mM DTT, pH: 7.5
Experiment:	SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2022 Nov 17

...2 to promote cancer cell survival versus cell death. Commun Biol 7(1):982 (2024)
Aplin C, Zielinski KA, Pabit S, Ogunribido D, Katt WP, Pollack L, Cerione RA, Milano SK

R_g^Guinier	3.9	nm
D_max	18.5	nm
Volume^Porod	134	nm³

SASDTE4 – ...26 (2% DMSO)

Sample:	Protein-glutamine gamma-glutamyltransferase 2 , 77 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 100 mM NaCl, 10% glycerol, 1 mM DTT, pH: 7.5
Experiment:	SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2022 Nov 17

...2 to promote cancer cell survival versus cell death. Commun Biol 7(1):982 (2024)
Aplin C, Zielinski KA, Pabit S, Ogunribido D, Katt WP, Pollack L, Cerione RA, Milano SK

R_g^Guinier	3.8	nm
D_max	17.6	nm
Volume^Porod	130	nm³

SASDTF4 – ...2 + inhibitor 5826: Equilibrium

Sample:	Protein-glutamine gamma-glutamyltransferase 2 , 77 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 100 mM NaCl, 10% glycerol, 1 mM DTT, 2 mM CaCl2, 50 µM 5826 inhibitor, pH: 7.5
Experiment:	SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2022 Nov 17

...2 to promote cancer cell survival versus cell death. Commun Biol 7(1):982 (2024)
Aplin C, Zielinski KA, Pabit S, Ogunribido D, Katt WP, Pollack L, Cerione RA, Milano SK

R_g^Guinier	6.7	nm
D_max	39.0	nm
Volume^Porod	450	nm³

SASDTG4 – ...2 + inhibitor 5826 + GTP: Equilibrium

Sample:	Protein-glutamine gamma-glutamyltransferase 2 , 77 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 100 mM NaCl, 10% glycerol, 1 mM DTT, 2 mM CaCl2, 50 µM 5826, 5 mM GTP, pH: 7.5
Experiment:	SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2022 Nov 17

...2 to promote cancer cell survival versus cell death. Commun Biol 7(1):982 (2024)
Aplin C, Zielinski KA, Pabit S, Ogunribido D, Katt WP, Pollack L, Cerione RA, Milano SK

R_g^Guinier	6.0	nm
D_max	29.0	nm
Volume^Porod	248	nm³

SASDTH4 – Tissue Transglutaminase + 1% DMSO

Sample:	Protein-glutamine gamma-glutamyltransferase 2 , 77 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 100 mM NaCl, 10% glycerol, 1 mM DTT, pH: 7.5
Experiment:	SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2022 Nov 17

...2 to promote cancer cell survival versus cell death. Commun Biol 7(1):982 (2024)
Aplin C, Zielinski KA, Pabit S, Ogunribido D, Katt WP, Pollack L, Cerione RA, Milano SK

R_g^Guinier	4.0	nm
D_max	18.5	nm
Volume^Porod	139	nm³

SASDTJ4 – ...2% DMSO

Sample:	Protein-glutamine gamma-glutamyltransferase 2 , 77 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 100 mM NaCl, 10% glycerol, 1 mM DTT, pH: 7.5
Experiment:	SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2022 Nov 17

...2 to promote cancer cell survival versus cell death. Commun Biol 7(1):982 (2024)
Aplin C, Zielinski KA, Pabit S, Ogunribido D, Katt WP, Pollack L, Cerione RA, Milano SK

R_g^Guinier	3.9	nm
D_max	18.5	nm
Volume^Porod	133	nm³

SASDTK4 – Tissue Transglutaminase + 5% DMSO

Sample:	Protein-glutamine gamma-glutamyltransferase 2 , 77 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 100 mM NaCl, 10% glycerol, 1 mM DTT, pH: 7.5
Experiment:	SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2022 Nov 17

...2 to promote cancer cell survival versus cell death. Commun Biol 7(1):982 (2024)
Aplin C, Zielinski KA, Pabit S, Ogunribido D, Katt WP, Pollack L, Cerione RA, Milano SK

R_g^Guinier	3.9	nm
D_max	18.5	nm
Volume^Porod	133	nm³

SASDTL4 – Tissue Transglutaminase + 10% DMSO

Sample:	Protein-glutamine gamma-glutamyltransferase 2 , 77 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 100 mM NaCl, 10% glycerol, 1 mM DTT, pH: 7.5
Experiment:	SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2022 Nov 17

...2 to promote cancer cell survival versus cell death. Commun Biol 7(1):982 (2024)
Aplin C, Zielinski KA, Pabit S, Ogunribido D, Katt WP, Pollack L, Cerione RA, Milano SK

R_g^Guinier	4.1	nm
D_max	21.5	nm
Volume^Porod	148	nm³

SASDTM4 – Tissue Transglutaminase R580K mutant

Protein-glutamine gamma-glutamyltransferase 2 (R580K) experimental SAS data

Protein-glutamine gamma-glutamyltransferase 2 (R580K) Kratky plot

Sample:	Protein-glutamine gamma-glutamyltransferase 2 (R580K) , 77 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 100 mM NaCl, 10% glycerol, 1 mM DTT, pH: 7.5
Experiment:	SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2022 Nov 17

...2 to promote cancer cell survival versus cell death. Commun Biol 7(1):982 (2024)
Aplin C, Zielinski KA, Pabit S, Ogunribido D, Katt WP, Pollack L, Cerione RA, Milano SK

R_g^Guinier	6.1	nm
D_max	32.0	nm
Volume^Porod	488	nm³

SASDTN4 – Tissue Transglutaminase R580K mutant + 100 µM GTP

Sample:	Protein-glutamine gamma-glutamyltransferase 2 (R580K) , 77 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 100 mM NaCl, 10% glycerol, 1 mM DTT, pH: 7.5
Experiment:	SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2022 Nov 17

...2 to promote cancer cell survival versus cell death. Commun Biol 7(1):982 (2024)
Aplin C, Zielinski KA, Pabit S, Ogunribido D, Katt WP, Pollack L, Cerione RA, Milano SK

R_g^Guinier	5.9	nm
D_max	27.0	nm
Volume^Porod	381	nm³

SASDTP4 – Tissue Transglutaminase R580K mutant + 1 mM GTP

Sample:	Protein-glutamine gamma-glutamyltransferase 2 (R580K) , 77 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 100 mM NaCl, 10% glycerol, 1 mM DTT, pH: 7.5
Experiment:	SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2022 Nov 17

...2 to promote cancer cell survival versus cell death. Commun Biol 7(1):982 (2024)
Aplin C, Zielinski KA, Pabit S, Ogunribido D, Katt WP, Pollack L, Cerione RA, Milano SK

R_g^Guinier	5.7	nm
D_max	30.0	nm
Volume^Porod	283	nm³

SASDTQ4 – ...2 mM GTP

Sample:	Protein-glutamine gamma-glutamyltransferase 2 (R580K) , 77 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 100 mM NaCl, 10% glycerol, 1 mM DTT, pH: 7.5
Experiment:	SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2022 Nov 17

...2 to promote cancer cell survival versus cell death. Commun Biol 7(1):982 (2024)
Aplin C, Zielinski KA, Pabit S, Ogunribido D, Katt WP, Pollack L, Cerione RA, Milano SK

R_g^Guinier	5.3	nm
D_max	25.0	nm
Volume^Porod	264	nm³

SASDTR4 – Tissue Transglutaminase R580K mutant + 5 mM GTP

Sample:	Protein-glutamine gamma-glutamyltransferase 2 (R580K) , 77 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 100 mM NaCl, 10% glycerol, 1 mM DTT, pH: 7.5
Experiment:	SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2022 Nov 17

...2 to promote cancer cell survival versus cell death. Commun Biol 7(1):982 (2024)
Aplin C, Zielinski KA, Pabit S, Ogunribido D, Katt WP, Pollack L, Cerione RA, Milano SK

R_g^Guinier	5.2	nm
D_max	25.0	nm
Volume^Porod	243	nm³

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