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3 hits found for Ubiquilin-2

SASDSA6 – ...Ubiquilin-2 (UBQLN2)

Ubiquilin-2 experimental SAS data
Ubiquilin-2 Kratky plot
Sample: Ubiquilin-2 dimer, 131 kDa Homo sapiens protein
Buffer: 20 mM sodium phosphate, 0.5 mM EDTA, 0.02 % NaN3, pH: 6.8
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2022 Jun 8
Short disordered N-termini & proline-rich domain are major regulators of UBQLN1/2/4 phase separation. Biophys J (2023)
Dao TP, Rajendran A, Galagedera SKK, Haws W, Castañeda CA
RgGuinier 5.2 nm
Dmax 22.5 nm
VolumePorod 330 nm3

SASDSG6 – ...Ubiquilin-2, ∆STI1-2 domain deletion (UBQLN2∆STI1-2)

Ubiquilin-2 (∆379-462) experimental SAS data
Ubiquilin-2 (∆379-462) Kratky plot
Sample: Ubiquilin-2 (∆379-462) monomer, 56 kDa Homo sapiens protein
Buffer: 20 mM sodium phosphate, 0.5 mM EDTA, 0.02 % NaN3, pH: 6.8
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2022 Jun 8
Short disordered N-termini & proline-rich domain are major regulators of UBQLN1/2/4 phase separation.
Sarasi Galagedera
RgGuinier 4.4 nm
Dmax 22.4 nm
VolumePorod 121 nm3

SASDSH6 – ...Ubiquilin-2, PXX domain deletion (UBQLN2∆PXX)

Ubiquilin-2 (∆487-538) experimental SAS data
Ubiquilin-2 (∆487-538) Kratky plot
Sample: Ubiquilin-2 (∆487-538) dimer, 122 kDa Homo sapiens protein
Buffer: 20 mM sodium phosphate, 0.5 mM EDTA, 0.02 % NaN3, pH: 6.8
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2022 Jun 8
Short disordered N-termini & proline-rich domain are major regulators of UBQLN1/2/4 phase separation.
Sarasi Galagedera
RgGuinier 4.8 nm
Dmax 19.5 nm
VolumePorod 288 nm3