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3 hits found for aD11 Fab

SASDAS5ad11 Fab

aD11 Fab experimental SAS data
DAMMIN model
Sample: aD11 Fab dimer, 50 kDa Mus musculus protein
Buffer: 50 mM Na-phosphate 1mM ethylenediaminetetraacetic aci, pH: 7
Experiment: SAXS data collected at EMBL X33, DORIS III, DESY on 2005 Oct 20
Dissecting NGF interactions with TrkA and p75 receptors by structural and functional studies of an anti-NGF neutralizing antibody. J Mol Biol 381(4):881-96 (2008)
Covaceuszach S, Cassetta A, Konarev PV, Gonfloni S, Rudolph R, Svergun DI, Lamba D, Cattaneo A
RgGuinier 2.6 nm
Dmax 8.0 nm
VolumePorod 95 nm3

SASDAT5 – NGF

NGF experimental SAS data
DAMMIN model
Sample: NGF dimer, 50 kDa Mus musculus protein
Buffer: 10 mM Na-phosphate 150 mM NaCl, pH: 7.8
Experiment: SAXS data collected at EMBL X33, DORIS III, DESY on 2005 Oct 20
Dissecting NGF interactions with TrkA and p75 receptors by structural and functional studies of an anti-NGF neutralizing antibody. J Mol Biol 381(4):881-96 (2008)
Covaceuszach S, Cassetta A, Konarev PV, Gonfloni S, Rudolph R, Svergun DI, Lamba D, Cattaneo A
RgGuinier 3.1 nm
Dmax 12.0 nm
VolumePorod 102 nm3

SASDAU5ad11 Fab + NGF

aD11 FabNGF experimental SAS data
DAMMIN model
Sample: aD11 Fab dimer, 50 kDa Mus musculus protein
NGF dimer, 50 kDa Mus musculus protein
Buffer: 30 mM Na-phosphate 75 mM NaCl, pH: 7
Experiment: SAXS data collected at EMBL X33, DORIS III, DESY on 2005 Dec 20
Dissecting NGF interactions with TrkA and p75 receptors by structural and functional studies of an anti-NGF neutralizing antibody. J Mol Biol 381(4):881-96 (2008)
Covaceuszach S, Cassetta A, Konarev PV, Gonfloni S, Rudolph R, Svergun DI, Lamba D, Cattaneo A
RgGuinier 4.3 nm
Dmax 16.0 nm
VolumePorod 255 nm3