Synchrotron SAXS data from solutions of the DNA binding and transactivation domains of hepatocyte nuclear factor 1-alpha in 4 mM Tris, 100 mM NaCl, 1 mM TCEP, pH 8.5 were collected on the CoSAXS beam line at MAX IV (Lund, Sweden) using a Eiger2 4M detector at a wavelength of λ = 0.1 nm (I(s) vs s, where s = 4πsinθ/λ, and 2θ is the scattering angle). One solute concentration of 2.50 mg/ml was measured at 10°C. 300 successive 0.020 second frames were collected. The data were normalized to the intensity of the transmitted beam and radially averaged; the scattering of the solvent-blank was subtracted.