SAXS data from solutions of calcium/calmodulin-dependent protein kinase type II alpha (CaMKIIα) 6x hub domain with PIPA in 20 mM MES, 150 mM NaCl, 1 mM DTT, 200 µM PIPA, pH 6 were collected using a Xenocs BioXolver L with MetalJet (University of Copenhagen, Department of Drug Design and Pharmacology) equipped with a Pilatus3 R 300K detector at a sample-detector distance of 0.6 m and at a wavelength of λ = 0.13402 nm (I(s) vs s, where s = 4πsinθ/λ, and 2θ is the scattering angle). One solute concentration of 6.70 mg/ml was measured at 25°C. 40 successive 60 second frames were collected. The data were normalized to the intensity of the transmitted beam and radially averaged; the scattering of the solvent-blank was subtracted.
The data is a merge from data collected at two different configurations. In addition to the listed, data was collected on the same sample with sample-detector distance 1.4558 m (60 frames of 120 s exposure). The resulting data is a merge of the data from the two configurations. The data was collected for comparison with the CaMKIIa 6x hub domain without ligands present.
![Calcium/calmodulin-dependent protein kinase type II subunit alpha (T354N, E355Q, T412N, I414M, I464H, F467M) 2-(6-(4-chlorophenyl)imidazo[1,2-b]pyridazine-2-yl)acetic acid small angle scattering data](/media/intensities_files/scattering_plots/SASDU65_dat_img.png)
s, nm-1
![Calcium/calmodulin-dependent protein kinase type II subunit alpha (T354N, E355Q, T412N, I414M, I464H, F467M) 2-(6-(4-chlorophenyl)imidazo[1,2-b]pyridazine-2-yl)acetic acid Guinier plot](/media//intensities_files/scattering_plots/SASDU65_guinier_img.png)
![Calcium/calmodulin-dependent protein kinase type II subunit alpha (T354N, E355Q, T412N, I414M, I464H, F467M) 2-(6-(4-chlorophenyl)imidazo[1,2-b]pyridazine-2-yl)acetic acid Kratky plot](/media/intensities_files/scattering_plots/SASDU65_kratky_img.png)
