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37 hits found for Bennett

SASDTZ9 – HIV-1 Envelope Glycoprotein SOSIP from a CH505 isolate 53 weeks post-infection at 25 °C

CH505TFchim.6R.SOSIP.664 Env glycoprotein experimental SAS data
CH505TFchim.6R.SOSIP.664 Env glycoprotein Kratky plot
Sample: CH505TFchim.6R.SOSIP.664 Env glycoprotein trimer, 217 kDa HIV-1 group M protein
Buffer: 15 mM HEPES, 150 mM NaCl, pH: 7.1
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2017 Jun 1
Microsecond dynamics control the HIV-1 Envelope conformation. Sci Adv 10(5):eadj0396 (2024)
Bennett AL, Edwards R, Kosheleva I, Saunders C, Bililign Y, Williams A, Bubphamala P, Manosouri K, Anasti K, Saunders KO, Alam SM, Haynes BF, Acharya P, Henderson R
RgGuinier 5.4 nm
Dmax 16.7 nm
VolumePorod 768 nm3

SASDU22 – HIV-1 Envelope Glycoprotein SOSIP from a CH505 isolate 78 weeks post-infection at 25 °C

CH505TFchim.6R.SOSIP.664 Env glycoprotein experimental SAS data
CH505TFchim.6R.SOSIP.664 Env glycoprotein Kratky plot
Sample: CH505TFchim.6R.SOSIP.664 Env glycoprotein trimer, 217 kDa HIV-1 group M protein
Buffer: 15 mM HEPES, 150 mM NaCl, pH: 7.1
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2017 Jun 1
Microsecond dynamics control the HIV-1 Envelope conformation. Sci Adv 10(5):eadj0396 (2024)
Bennett AL, Edwards R, Kosheleva I, Saunders C, Bililign Y, Williams A, Bubphamala P, Manosouri K, Anasti K, Saunders KO, Alam SM, Haynes BF, Acharya P, Henderson R
RgGuinier 5.1 nm
Dmax 16.0 nm
VolumePorod 709 nm3

SASDU32 – HIV-1 Envelope Glycoprotein SOSIP from a CH505 isolate 100 weeks post-infection at 25 °C

CH505TFchim.6R.SOSIP.664 Env glycoprotein experimental SAS data
CH505TFchim.6R.SOSIP.664 Env glycoprotein Kratky plot
Sample: CH505TFchim.6R.SOSIP.664 Env glycoprotein trimer, 217 kDa HIV-1 group M protein
Buffer: 15 mM HEPES, 150 mM NaCl, pH: 7.1
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2017 Jun 1
Microsecond dynamics control the HIV-1 Envelope conformation. Sci Adv 10(5):eadj0396 (2024)
Bennett AL, Edwards R, Kosheleva I, Saunders C, Bililign Y, Williams A, Bubphamala P, Manosouri K, Anasti K, Saunders KO, Alam SM, Haynes BF, Acharya P, Henderson R
RgGuinier 5.2 nm
Dmax 17.2 nm
VolumePorod 770 nm3

SASDU42 – HIV-1 Envelope Glycoprotein SOSIP from a BG505 isolate containing T332N mutation at 25 °C

BG505SOSIP.664T332N Env glycoprotein experimental SAS data
BG505SOSIP.664T332N Env glycoprotein Kratky plot
Sample: BG505SOSIP.664T332N Env glycoprotein trimer, 213 kDa HIV-1 group M protein
Buffer: 15 mM HEPES, 150 mM NaCl, pH: 7.1
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2017 Jun 1
Microsecond dynamics control the HIV-1 Envelope conformation. Sci Adv 10(5):eadj0396 (2024)
Bennett AL, Edwards R, Kosheleva I, Saunders C, Bililign Y, Williams A, Bubphamala P, Manosouri K, Anasti K, Saunders KO, Alam SM, Haynes BF, Acharya P, Henderson R
RgGuinier 5.0 nm
Dmax 20.7 nm
VolumePorod 712 nm3

SASDMG4 – Arrestin-3 ERK2 fusion, monomer (Arrestin-3 fused to extracellular signal-regulated kinase 2)

Arrestin-3 fused to extracellular signal-regulated kinase 2 experimental SAS data
Arrestin-3 ERK2 fusion, monomer (Arrestin-3 fused to extracellular signal-regulated kinase 2) Rg histogram
Sample: Arrestin-3 fused to extracellular signal-regulated kinase 2 monomer, 89 kDa Bos taurus/Rattus norvegicus protein
Buffer: 20 mM MOPS pH 7.5, 150 mM NaCl, 1 mM TCEP, and 5% glycerol, pH: 7.5
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2019 Mar 23
The two non-visual arrestins engage ERK2 differently. J Mol Biol :167465 (2022)
...Bennett Hopkins J, Zhuo Y, Zheng C, Perez I, Schultz KM, Vishnivetskiy SA, Kaya AI, Sharma P, Dalby KN, Young Chung K, Klug CS, Gurevich VV, Iverson TM
RgGuinier 3.6 nm
Dmax 14.0 nm

SASDMH4 – Arrestin-3 ERK2 fusion, dimer (Arrestin-3 fused to extracellular signal-regulated kinase 2)

Arrestin-3 fused to extracellular signal-regulated kinase 2 experimental SAS data
Arrestin-3 fused to extracellular signal-regulated kinase 2 Kratky plot
Sample: Arrestin-3 fused to extracellular signal-regulated kinase 2 dimer, 178 kDa Bos taurus/Rattus norvegicus protein
Buffer: 20 mM MOPS pH 7.5, 150 mM NaCl, 1 mM TCEP, and 5% glycerol, pH: 7.5
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2019 Mar 23
The two non-visual arrestins engage ERK2 differently. J Mol Biol :167465 (2022)
...Bennett Hopkins J, Zhuo Y, Zheng C, Perez I, Schultz KM, Vishnivetskiy SA, Kaya AI, Sharma P, Dalby KN, Young Chung K, Klug CS, Gurevich VV, Iverson TM
RgGuinier 4.3 nm
Dmax 16.0 nm

SASDT29 – HIV-1 Envelope Glycoprotein SOSIP from a transmitted founder virus of the CH505 isolate at 25 °C

CH505TFchim.6R.SOSIP.664 Env glycoprotein experimental SAS data
CH505TFchim.6R.SOSIP.664 Env glycoprotein Kratky plot
Sample: CH505TFchim.6R.SOSIP.664 Env glycoprotein trimer, 217 kDa HIV-1 group M protein
Buffer: 15 mM HEPES, 150 mM NaCl, pH: 7.1
Experiment: SAXS data collected at 14-ID-B (BioCARS), Advanced Photon Source (APS), Argonne National Laboratory on 2022 Jul 27
Microsecond dynamics control the HIV-1 Envelope conformation. Sci Adv 10(5):eadj0396 (2024)
Bennett AL, Edwards R, Kosheleva I, Saunders C, Bililign Y, Williams A, Bubphamala P, Manosouri K, Anasti K, Saunders KO, Alam SM, Haynes BF, Acharya P, Henderson R
RgGuinier 4.6 nm
Dmax 15.5 nm
VolumePorod 705 nm3

SASDT39 – HIV-1 Envelope Glycoprotein SOSIP from a transmitted founder virus of the CH505 isolate at 35 °C

CH505TFchim.6R.SOSIP.664 Env glycoprotein experimental SAS data
CH505TFchim.6R.SOSIP.664 Env glycoprotein Kratky plot
Sample: CH505TFchim.6R.SOSIP.664 Env glycoprotein trimer, 217 kDa HIV-1 group M protein
Buffer: 15 mM HEPES, 150 mM NaCl, pH: 7.1
Experiment: SAXS data collected at 14-ID-B (BioCARS), Advanced Photon Source (APS), Argonne National Laboratory on 2022 Jul 27
Microsecond dynamics control the HIV-1 Envelope conformation. Sci Adv 10(5):eadj0396 (2024)
Bennett AL, Edwards R, Kosheleva I, Saunders C, Bililign Y, Williams A, Bubphamala P, Manosouri K, Anasti K, Saunders KO, Alam SM, Haynes BF, Acharya P, Henderson R
RgGuinier 4.6 nm
Dmax 15.4 nm
VolumePorod 704 nm3

SASDT49 – HIV-1 Envelope Glycoprotein SOSIP from a transmitted founder virus of the CH505 isolate at 44 °C

CH505TFchim.6R.SOSIP.664 Env glycoprotein experimental SAS data
CH505TFchim.6R.SOSIP.664 Env glycoprotein Kratky plot
Sample: CH505TFchim.6R.SOSIP.664 Env glycoprotein trimer, 217 kDa HIV-1 group M protein
Buffer: 15 mM HEPES, 150 mM NaCl, pH: 7.1
Experiment: SAXS data collected at 14-ID-B (BioCARS), Advanced Photon Source (APS), Argonne National Laboratory on 2022 Jul 27
Microsecond dynamics control the HIV-1 Envelope conformation. Sci Adv 10(5):eadj0396 (2024)
Bennett AL, Edwards R, Kosheleva I, Saunders C, Bililign Y, Williams A, Bubphamala P, Manosouri K, Anasti K, Saunders KO, Alam SM, Haynes BF, Acharya P, Henderson R
RgGuinier 4.6 nm
Dmax 15.6 nm
VolumePorod 702 nm3

SASDT59 – HIV-1 Envelope Glycoprotein SOSIP from a transmitted founder virus of the CH505 isolate at 50 °C

CH505TFchim.6R.SOSIP.664 Env glycoprotein experimental SAS data
CH505TFchim.6R.SOSIP.664 Env glycoprotein Kratky plot
Sample: CH505TFchim.6R.SOSIP.664 Env glycoprotein trimer, 217 kDa HIV-1 group M protein
Buffer: 15 mM HEPES, 150 mM NaCl, pH: 7.1
Experiment: SAXS data collected at 14-ID-B (BioCARS), Advanced Photon Source (APS), Argonne National Laboratory on 2022 Jul 29
Microsecond dynamics control the HIV-1 Envelope conformation. Sci Adv 10(5):eadj0396 (2024)
Bennett AL, Edwards R, Kosheleva I, Saunders C, Bililign Y, Williams A, Bubphamala P, Manosouri K, Anasti K, Saunders KO, Alam SM, Haynes BF, Acharya P, Henderson R
RgGuinier 4.6 nm
Dmax 15.6 nm
VolumePorod 699 nm3

SASDT69 – HIV-1 Envelope Glycoprotein SOSIP from a transmitted founder virus of the CH505 isolate 1.5 µs post temperature jump (44 °C - 50 °C)

CH505TFchim.6R.SOSIP.664 Env glycoprotein experimental SAS data
CH505TFchim.6R.SOSIP.664 Env glycoprotein Kratky plot
Sample: CH505TFchim.6R.SOSIP.664 Env glycoprotein trimer, 217 kDa HIV-1 group M protein
Buffer: 15 mM HEPES, 150 mM NaCl, pH: 7.1
Experiment: SAXS data collected at 14-ID-B (BioCARS), Advanced Photon Source (APS), Argonne National Laboratory on 2022 Jul 30
Microsecond dynamics control the HIV-1 Envelope conformation. Sci Adv 10(5):eadj0396 (2024)
Bennett AL, Edwards R, Kosheleva I, Saunders C, Bililign Y, Williams A, Bubphamala P, Manosouri K, Anasti K, Saunders KO, Alam SM, Haynes BF, Acharya P, Henderson R
RgGuinier 4.6 nm
Dmax 15.5 nm
VolumePorod 706 nm3

SASDT79 – HIV-1 Envelope Glycoprotein SOSIP from a transmitted founder virus of the CH505 isolate 3 µs post temperature jump (44 °C - 50 °C)

CH505TFchim.6R.SOSIP.664 Env glycoprotein experimental SAS data
CH505TFchim.6R.SOSIP.664 Env glycoprotein Kratky plot
Sample: CH505TFchim.6R.SOSIP.664 Env glycoprotein trimer, 217 kDa HIV-1 group M protein
Buffer: 15 mM HEPES, 150 mM NaCl, pH: 7.1
Experiment: SAXS data collected at 14-ID-B (BioCARS), Advanced Photon Source (APS), Argonne National Laboratory on 2022 Jul 30
Microsecond dynamics control the HIV-1 Envelope conformation. Sci Adv 10(5):eadj0396 (2024)
Bennett AL, Edwards R, Kosheleva I, Saunders C, Bililign Y, Williams A, Bubphamala P, Manosouri K, Anasti K, Saunders KO, Alam SM, Haynes BF, Acharya P, Henderson R
RgGuinier 4.6 nm
Dmax 15.5 nm
VolumePorod 706 nm3

SASDT89 – HIV-1 Envelope Glycoprotein SOSIP from a transmitted founder virus of the CH505 isolate 5 µs post temperature jump (44 °C - 50 °C)

CH505TFchim.6R.SOSIP.664 Env glycoprotein experimental SAS data
CH505TFchim.6R.SOSIP.664 Env glycoprotein Kratky plot
Sample: CH505TFchim.6R.SOSIP.664 Env glycoprotein trimer, 217 kDa HIV-1 group M protein
Buffer: 15 mM HEPES, 150 mM NaCl, pH: 7.1
Experiment: SAXS data collected at 14-ID-B (BioCARS), Advanced Photon Source (APS), Argonne National Laboratory on 2022 Jul 30
Microsecond dynamics control the HIV-1 Envelope conformation. Sci Adv 10(5):eadj0396 (2024)
Bennett AL, Edwards R, Kosheleva I, Saunders C, Bililign Y, Williams A, Bubphamala P, Manosouri K, Anasti K, Saunders KO, Alam SM, Haynes BF, Acharya P, Henderson R
RgGuinier 4.6 nm
Dmax 15.5 nm
VolumePorod 706 nm3

SASDT99 – HIV-1 Envelope Glycoprotein SOSIP from a transmitted founder virus of the CH505 isolate 10 µs post temperature jump (44 °C - 50 °C)

CH505TFchim.6R.SOSIP.664 Env glycoprotein experimental SAS data
CH505TFchim.6R.SOSIP.664 Env glycoprotein Kratky plot
Sample: CH505TFchim.6R.SOSIP.664 Env glycoprotein trimer, 217 kDa HIV-1 group M protein
Buffer: 15 mM HEPES, 150 mM NaCl, pH: 7.1
Experiment: SAXS data collected at 14-ID-B (BioCARS), Advanced Photon Source (APS), Argonne National Laboratory on 2022 Jul 28
Microsecond dynamics control the HIV-1 Envelope conformation. Sci Adv 10(5):eadj0396 (2024)
Bennett AL, Edwards R, Kosheleva I, Saunders C, Bililign Y, Williams A, Bubphamala P, Manosouri K, Anasti K, Saunders KO, Alam SM, Haynes BF, Acharya P, Henderson R
RgGuinier 4.3 nm
Dmax 15.3 nm
VolumePorod 729 nm3

SASDTA9 – HIV-1 Envelope Glycoprotein SOSIP from a transmitted founder virus of the CH505 isolate 50 µs post temperature jump (44 °C - 50 °C)

CH505TFchim.6R.SOSIP.664 Env glycoprotein experimental SAS data
CH505TFchim.6R.SOSIP.664 Env glycoprotein Kratky plot
Sample: CH505TFchim.6R.SOSIP.664 Env glycoprotein trimer, 217 kDa HIV-1 group M protein
Buffer: 15 mM HEPES, 150 mM NaCl, pH: 7.1
Experiment: SAXS data collected at 14-ID-B (BioCARS), Advanced Photon Source (APS), Argonne National Laboratory on 2022 Jul 28
Microsecond dynamics control the HIV-1 Envelope conformation. Sci Adv 10(5):eadj0396 (2024)
Bennett AL, Edwards R, Kosheleva I, Saunders C, Bililign Y, Williams A, Bubphamala P, Manosouri K, Anasti K, Saunders KO, Alam SM, Haynes BF, Acharya P, Henderson R
RgGuinier 4.3 nm
Dmax 15.4 nm
VolumePorod 729 nm3

SASDTB9 – HIV-1 Envelope Glycoprotein SOSIP from a transmitted founder virus of the CH505 isolate 100 µs post temperature jump (44 °C - 50 °C)

CH505TFchim.6R.SOSIP.664 Env glycoprotein experimental SAS data
CH505TFchim.6R.SOSIP.664 Env glycoprotein Kratky plot
Sample: CH505TFchim.6R.SOSIP.664 Env glycoprotein trimer, 217 kDa HIV-1 group M protein
Buffer: 15 mM HEPES, 150 mM NaCl, pH: 7.1
Experiment: SAXS data collected at 14-ID-B (BioCARS), Advanced Photon Source (APS), Argonne National Laboratory on 2022 Jul 28
Microsecond dynamics control the HIV-1 Envelope conformation. Sci Adv 10(5):eadj0396 (2024)
Bennett AL, Edwards R, Kosheleva I, Saunders C, Bililign Y, Williams A, Bubphamala P, Manosouri K, Anasti K, Saunders KO, Alam SM, Haynes BF, Acharya P, Henderson R
RgGuinier 4.3 nm
Dmax 15.3 nm
VolumePorod 730 nm3

SASDTC9 – HIV-1 Envelope Glycoprotein SOSIP from a transmitted founder virus of the CH505 isolate 500 µs post temperature jump (44 °C - 50 °C)

CH505TFchim.6R.SOSIP.664 Env glycoprotein experimental SAS data
CH505TFchim.6R.SOSIP.664 Env glycoprotein Kratky plot
Sample: CH505TFchim.6R.SOSIP.664 Env glycoprotein trimer, 217 kDa HIV-1 group M protein
Buffer: 15 mM HEPES, 150 mM NaCl, pH: 7.1
Experiment: SAXS data collected at 14-ID-B (BioCARS), Advanced Photon Source (APS), Argonne National Laboratory on 2022 Jul 28
Microsecond dynamics control the HIV-1 Envelope conformation. Sci Adv 10(5):eadj0396 (2024)
Bennett AL, Edwards R, Kosheleva I, Saunders C, Bililign Y, Williams A, Bubphamala P, Manosouri K, Anasti K, Saunders KO, Alam SM, Haynes BF, Acharya P, Henderson R
RgGuinier 4.3 nm
Dmax 15.3 nm
VolumePorod 728 nm3

SASDTD9 – HIV-1 Envelope Glycoprotein SOSIP from a transmitted founder virus of the CH505 isolate 1 ms (20 Hz) post temperature jump (44 °C - 50 °C)

CH505TFchim.6R.SOSIP.664 Env glycoprotein experimental SAS data
CH505TFchim.6R.SOSIP.664 Env glycoprotein Kratky plot
Sample: CH505TFchim.6R.SOSIP.664 Env glycoprotein trimer, 217 kDa HIV-1 group M protein
Buffer: 15 mM HEPES, 150 mM NaCl, pH: 7.1
Experiment: SAXS data collected at 14-ID-B (BioCARS), Advanced Photon Source (APS), Argonne National Laboratory on 2022 Jul 28
Microsecond dynamics control the HIV-1 Envelope conformation. Sci Adv 10(5):eadj0396 (2024)
Bennett AL, Edwards R, Kosheleva I, Saunders C, Bililign Y, Williams A, Bubphamala P, Manosouri K, Anasti K, Saunders KO, Alam SM, Haynes BF, Acharya P, Henderson R
RgGuinier 4.3 nm
Dmax 15.3 nm
VolumePorod 742 nm3

SASDTE9 – HIV-1 Envelope Glycoprotein SOSIP from a transmitted founder virus of the CH505 isolate 1 ms (5 Hz) post temperature jump (44 °C - 50 °C)

CH505TFchim.6R.SOSIP.664 Env glycoprotein experimental SAS data
CH505TFchim.6R.SOSIP.664 Env glycoprotein Kratky plot
Sample: CH505TFchim.6R.SOSIP.664 Env glycoprotein trimer, 217 kDa HIV-1 group M protein
Buffer: 15 mM HEPES, 150 mM NaCl, pH: 7.1
Experiment: SAXS data collected at 14-ID-B (BioCARS), Advanced Photon Source (APS), Argonne National Laboratory on 2022 Jul 29
Microsecond dynamics control the HIV-1 Envelope conformation. Sci Adv 10(5):eadj0396 (2024)
Bennett AL, Edwards R, Kosheleva I, Saunders C, Bililign Y, Williams A, Bubphamala P, Manosouri K, Anasti K, Saunders KO, Alam SM, Haynes BF, Acharya P, Henderson R
RgGuinier 4.1 nm
Dmax 15.4 nm
VolumePorod 706 nm3

SASDTF9 – HIV-1 Envelope Glycoprotein SOSIP from a transmitted founder virus of the CH505 isolate 10 ms post temperature jump (44 °C - 50 °C)

CH505TFchim.6R.SOSIP.664 Env glycoprotein experimental SAS data
CH505TFchim.6R.SOSIP.664 Env glycoprotein Kratky plot
Sample: CH505TFchim.6R.SOSIP.664 Env glycoprotein trimer, 217 kDa HIV-1 group M protein
Buffer: 15 mM HEPES, 150 mM NaCl, pH: 7.1
Experiment: SAXS data collected at 14-ID-B (BioCARS), Advanced Photon Source (APS), Argonne National Laboratory on 2022 Jul 29
Microsecond dynamics control the HIV-1 Envelope conformation. Sci Adv 10(5):eadj0396 (2024)
Bennett AL, Edwards R, Kosheleva I, Saunders C, Bililign Y, Williams A, Bubphamala P, Manosouri K, Anasti K, Saunders KO, Alam SM, Haynes BF, Acharya P, Henderson R
RgGuinier 4.1 nm
Dmax 15.4 nm
VolumePorod 706 nm3

SASDTG9 – HIV-1 Envelope Glycoprotein SOSIP from a transmitted founder virus of the CH505 isolate 100 ms post temperature jump (44 °C - 50 °C)

CH505TFchim.6R.SOSIP.664 Env glycoprotein experimental SAS data
CH505TFchim.6R.SOSIP.664 Env glycoprotein Kratky plot
Sample: CH505TFchim.6R.SOSIP.664 Env glycoprotein trimer, 217 kDa HIV-1 group M protein
Buffer: 15 mM HEPES, 150 mM NaCl, pH: 7.1
Experiment: SAXS data collected at 14-ID-B (BioCARS), Advanced Photon Source (APS), Argonne National Laboratory on 2022 Jul 29
Microsecond dynamics control the HIV-1 Envelope conformation. Sci Adv 10(5):eadj0396 (2024)
Bennett AL, Edwards R, Kosheleva I, Saunders C, Bililign Y, Williams A, Bubphamala P, Manosouri K, Anasti K, Saunders KO, Alam SM, Haynes BF, Acharya P, Henderson R
RgGuinier 4.1 nm
Dmax 15.5 nm
VolumePorod 706 nm3

SASDTH9 – HIV-1 Envelope Glycoprotein SOSIP from the CH848 isolate at 30 °C

CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 Env glycoprotein experimental SAS data
CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 Env glycoprotein Kratky plot
Sample: CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 Env glycoprotein trimer, 211 kDa HIV-1 group M protein
Buffer: 15 mM HEPES, 150 mM NaCl, pH: 7.1
Experiment: SAXS data collected at 14-ID-B (BioCARS), Advanced Photon Source (APS), Argonne National Laboratory on 2023 Mar 28
Microsecond dynamics control the HIV-1 Envelope conformation. Sci Adv 10(5):eadj0396 (2024)
Bennett AL, Edwards R, Kosheleva I, Saunders C, Bililign Y, Williams A, Bubphamala P, Manosouri K, Anasti K, Saunders KO, Alam SM, Haynes BF, Acharya P, Henderson R
RgGuinier 4.1 nm
Dmax 15.3 nm
VolumePorod 768 nm3

SASDTJ9 – HIV-1 Envelope Glycoprotein SOSIP from the CH848 isolate at 35 °C

CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 Env glycoprotein experimental SAS data
CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 Env glycoprotein Kratky plot
Sample: CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 Env glycoprotein trimer, 211 kDa HIV-1 group M protein
Buffer: 15 mM HEPES, 150 mM NaCl, pH: 7.1
Experiment: SAXS data collected at 14-ID-B (BioCARS), Advanced Photon Source (APS), Argonne National Laboratory on 2023 Mar 28
Microsecond dynamics control the HIV-1 Envelope conformation. Sci Adv 10(5):eadj0396 (2024)
Bennett AL, Edwards R, Kosheleva I, Saunders C, Bililign Y, Williams A, Bubphamala P, Manosouri K, Anasti K, Saunders KO, Alam SM, Haynes BF, Acharya P, Henderson R
RgGuinier 5.3 nm
Dmax 15.3 nm
VolumePorod 765 nm3

SASDTK9 – HIV-1 Envelope Glycoprotein SOSIP from the CH848 isolate at 40 °C

CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 Env glycoprotein experimental SAS data
CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 Env glycoprotein Kratky plot
Sample: CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 Env glycoprotein trimer, 211 kDa HIV-1 group M protein
Buffer: 15 mM HEPES, 150 mM NaCl, pH: 7.1
Experiment: SAXS data collected at 14-ID-B (BioCARS), Advanced Photon Source (APS), Argonne National Laboratory on 2023 Mar 28
Microsecond dynamics control the HIV-1 Envelope conformation. Sci Adv 10(5):eadj0396 (2024)
Bennett AL, Edwards R, Kosheleva I, Saunders C, Bililign Y, Williams A, Bubphamala P, Manosouri K, Anasti K, Saunders KO, Alam SM, Haynes BF, Acharya P, Henderson R
RgGuinier 5.3 nm
Dmax 15.3 nm
VolumePorod 764 nm3

SASDTL9 – HIV-1 Envelope Glycoprotein SOSIP from the CH848 isolate at 44 °C

CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 Env glycoprotein experimental SAS data
CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 Env glycoprotein Kratky plot
Sample: CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 Env glycoprotein trimer, 211 kDa HIV-1 group M protein
Buffer: 15 mM HEPES, 150 mM NaCl, pH: 7.1
Experiment: SAXS data collected at 14-ID-B (BioCARS), Advanced Photon Source (APS), Argonne National Laboratory on 2023 Mar 28
Microsecond dynamics control the HIV-1 Envelope conformation. Sci Adv 10(5):eadj0396 (2024)
Bennett AL, Edwards R, Kosheleva I, Saunders C, Bililign Y, Williams A, Bubphamala P, Manosouri K, Anasti K, Saunders KO, Alam SM, Haynes BF, Acharya P, Henderson R
RgGuinier 5.2 nm
Dmax 15.2 nm
VolumePorod 728 nm3

SASDTM9 – HIV-1 Envelope Glycoprotein SOSIP from the CH848 isolate 5 µs post temperature jump (44 °C - 50 °C)

CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 Env glycoprotein experimental SAS data
CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 Env glycoprotein Kratky plot
Sample: CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 Env glycoprotein trimer, 211 kDa HIV-1 group M protein
Buffer: 15 mM HEPES, 150 mM NaCl, pH: 7.1
Experiment: SAXS data collected at 14-ID-B (BioCARS), Advanced Photon Source (APS), Argonne National Laboratory on 2023 Mar 30
Microsecond dynamics control the HIV-1 Envelope conformation. Sci Adv 10(5):eadj0396 (2024)
Bennett AL, Edwards R, Kosheleva I, Saunders C, Bililign Y, Williams A, Bubphamala P, Manosouri K, Anasti K, Saunders KO, Alam SM, Haynes BF, Acharya P, Henderson R
RgGuinier 5.3 nm
Dmax 15.1 nm
VolumePorod 750 nm3

SASDTN9 – HIV-1 Envelope Glycoprotein SOSIP from the CH848 isolate 10 µs post temperature jump (44 °C - 50 °C)

CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 Env glycoprotein experimental SAS data
CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 Env glycoprotein Kratky plot
Sample: CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 Env glycoprotein trimer, 211 kDa HIV-1 group M protein
Buffer: 15 mM HEPES, 150 mM NaCl, pH: 7.1
Experiment: SAXS data collected at 14-ID-B (BioCARS), Advanced Photon Source (APS), Argonne National Laboratory on 2023 Mar 30
Microsecond dynamics control the HIV-1 Envelope conformation. Sci Adv 10(5):eadj0396 (2024)
Bennett AL, Edwards R, Kosheleva I, Saunders C, Bililign Y, Williams A, Bubphamala P, Manosouri K, Anasti K, Saunders KO, Alam SM, Haynes BF, Acharya P, Henderson R
RgGuinier 5.3 nm
Dmax 15.1 nm
VolumePorod 750 nm3

SASDTP9 – HIV-1 Envelope Glycoprotein SOSIP from the CH848 isolate 50 µs post temperature jump (44 °C - 50 °C)

CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 Env glycoprotein experimental SAS data
CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 Env glycoprotein Kratky plot
Sample: CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 Env glycoprotein trimer, 211 kDa HIV-1 group M protein
Buffer: 15 mM HEPES, 150 mM NaCl, pH: 7.1
Experiment: SAXS data collected at 14-ID-B (BioCARS), Advanced Photon Source (APS), Argonne National Laboratory on 2023 Mar 30
Microsecond dynamics control the HIV-1 Envelope conformation. Sci Adv 10(5):eadj0396 (2024)
Bennett AL, Edwards R, Kosheleva I, Saunders C, Bililign Y, Williams A, Bubphamala P, Manosouri K, Anasti K, Saunders KO, Alam SM, Haynes BF, Acharya P, Henderson R
RgGuinier 5.3 nm
Dmax 15.1 nm
VolumePorod 752 nm3

SASDTQ9 – HIV-1 Envelope Glycoprotein SOSIP from the CH848 isolate 100 µs post temperature jump (44 °C - 50 °C)

CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 Env glycoprotein experimental SAS data
CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 Env glycoprotein Kratky plot
Sample: CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 Env glycoprotein trimer, 211 kDa HIV-1 group M protein
Buffer: 15 mM HEPES, 150 mM NaCl, pH: 7.1
Experiment: SAXS data collected at 14-ID-B (BioCARS), Advanced Photon Source (APS), Argonne National Laboratory on 2023 Mar 30
Microsecond dynamics control the HIV-1 Envelope conformation. Sci Adv 10(5):eadj0396 (2024)
Bennett AL, Edwards R, Kosheleva I, Saunders C, Bililign Y, Williams A, Bubphamala P, Manosouri K, Anasti K, Saunders KO, Alam SM, Haynes BF, Acharya P, Henderson R
RgGuinier 5.3 nm
Dmax 15.1 nm
VolumePorod 755 nm3

SASDTR9 – HIV-1 Envelope Glycoprotein SOSIP from the CH848 isolate 250 µs post temperature jump (44 °C - 50 °C)

CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 Env glycoprotein experimental SAS data
CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 Env glycoprotein Kratky plot
Sample: CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 Env glycoprotein trimer, 211 kDa HIV-1 group M protein
Buffer: 15 mM HEPES, 150 mM NaCl, pH: 7.1
Experiment: SAXS data collected at 14-ID-B (BioCARS), Advanced Photon Source (APS), Argonne National Laboratory on 2023 Mar 30
Microsecond dynamics control the HIV-1 Envelope conformation. Sci Adv 10(5):eadj0396 (2024)
Bennett AL, Edwards R, Kosheleva I, Saunders C, Bililign Y, Williams A, Bubphamala P, Manosouri K, Anasti K, Saunders KO, Alam SM, Haynes BF, Acharya P, Henderson R
RgGuinier 5.3 nm
Dmax 15.3 nm
VolumePorod 741 nm3

SASDTS9 – HIV-1 Envelope Glycoprotein SOSIP from the CH848 isolate 500 µs post temperature jump (44 °C - 50 °C)

CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 Env glycoprotein experimental SAS data
CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 Env glycoprotein Kratky plot
Sample: CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 Env glycoprotein trimer, 211 kDa HIV-1 group M protein
Buffer: 15 mM HEPES, 150 mM NaCl, pH: 7.1
Experiment: SAXS data collected at 14-ID-B (BioCARS), Advanced Photon Source (APS), Argonne National Laboratory on 2023 Mar 30
Microsecond dynamics control the HIV-1 Envelope conformation. Sci Adv 10(5):eadj0396 (2024)
Bennett AL, Edwards R, Kosheleva I, Saunders C, Bililign Y, Williams A, Bubphamala P, Manosouri K, Anasti K, Saunders KO, Alam SM, Haynes BF, Acharya P, Henderson R
RgGuinier 5.3 nm
Dmax 15.1 nm
VolumePorod 750 nm3

SASDTT9 – HIV-1 Envelope Glycoprotein SOSIP from the CH848 isolate 750 µs post temperature jump (44 °C - 50 °C)

CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 Env glycoprotein experimental SAS data
CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 Env glycoprotein Kratky plot
Sample: CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 Env glycoprotein trimer, 211 kDa HIV-1 group M protein
Buffer: 15 mM HEPES, 150 mM NaCl, pH: 7.1
Experiment: SAXS data collected at 14-ID-B (BioCARS), Advanced Photon Source (APS), Argonne National Laboratory on 2023 Mar 30
Microsecond dynamics control the HIV-1 Envelope conformation. Sci Adv 10(5):eadj0396 (2024)
Bennett AL, Edwards R, Kosheleva I, Saunders C, Bililign Y, Williams A, Bubphamala P, Manosouri K, Anasti K, Saunders KO, Alam SM, Haynes BF, Acharya P, Henderson R
RgGuinier 5.3 nm
Dmax 15.3 nm
VolumePorod 739 nm3

SASDTU9 – HIV-1 Envelope Glycoprotein SOSIP from the CH848 isolate 1 ms post temperature jump (44 °C - 50 °C)

CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 Env glycoprotein experimental SAS data
CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 Env glycoprotein Kratky plot
Sample: CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 Env glycoprotein trimer, 211 kDa HIV-1 group M protein
Buffer: 15 mM HEPES, 150 mM NaCl, pH: 7.1
Experiment: SAXS data collected at 14-ID-B (BioCARS), Advanced Photon Source (APS), Argonne National Laboratory on 2023 Mar 30
Microsecond dynamics control the HIV-1 Envelope conformation. Sci Adv 10(5):eadj0396 (2024)
Bennett AL, Edwards R, Kosheleva I, Saunders C, Bililign Y, Williams A, Bubphamala P, Manosouri K, Anasti K, Saunders KO, Alam SM, Haynes BF, Acharya P, Henderson R
RgGuinier 5.3 nm
Dmax 15.1 nm
VolumePorod 751 nm3

SASDTV9 – HIV-1 Envelope Glycoprotein SOSIP from the CH848 isolate 10 ms post temperature jump (44 °C - 50 °C)

CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 Env glycoprotein experimental SAS data
CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 Env glycoprotein Kratky plot
Sample: CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 Env glycoprotein trimer, 211 kDa HIV-1 group M protein
Buffer: 15 mM HEPES, 150 mM NaCl, pH: 7.1
Experiment: SAXS data collected at 14-ID-B (BioCARS), Advanced Photon Source (APS), Argonne National Laboratory on 2023 Mar 30
Microsecond dynamics control the HIV-1 Envelope conformation. Sci Adv 10(5):eadj0396 (2024)
Bennett AL, Edwards R, Kosheleva I, Saunders C, Bililign Y, Williams A, Bubphamala P, Manosouri K, Anasti K, Saunders KO, Alam SM, Haynes BF, Acharya P, Henderson R
RgGuinier 5.3 nm
Dmax 15.5 nm
VolumePorod 733 nm3

SASDTW9 – HIV-1 Envelope Glycoprotein SOSIP from the CH848 isolate 100 ms post temperature jump (44 °C - 50 °C)

CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 Env glycoprotein experimental SAS data
CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 Env glycoprotein Kratky plot
Sample: CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 Env glycoprotein trimer, 211 kDa HIV-1 group M protein
Buffer: 15 mM HEPES, 150 mM NaCl, pH: 7.1
Experiment: SAXS data collected at 14-ID-B (BioCARS), Advanced Photon Source (APS), Argonne National Laboratory on 2023 Mar 30
Microsecond dynamics control the HIV-1 Envelope conformation. Sci Adv 10(5):eadj0396 (2024)
Bennett AL, Edwards R, Kosheleva I, Saunders C, Bililign Y, Williams A, Bubphamala P, Manosouri K, Anasti K, Saunders KO, Alam SM, Haynes BF, Acharya P, Henderson R
RgGuinier 5.3 nm
Dmax 15.3 nm
VolumePorod 732 nm3

SASDTX9 – HIV-1 Envelope Glycoprotein SOSIP from a transmitted founder virus of the CH505 isolate including the 4.1 stabilization mutations at 25 °C

CH505TF.6R.SOSIP.664.v4.1 Env glycoprotein experimental SAS data
CH505TF.6R.SOSIP.664.v4.1 Env glycoprotein Kratky plot
Sample: CH505TF.6R.SOSIP.664.v4.1 Env glycoprotein trimer, 218 kDa HIV-1 group M protein
Buffer: 15 mM HEPES, 150 mM NaCl, pH: 7.1
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2017 Jun 1
Microsecond dynamics control the HIV-1 Envelope conformation. Sci Adv 10(5):eadj0396 (2024)
Bennett AL, Edwards R, Kosheleva I, Saunders C, Bililign Y, Williams A, Bubphamala P, Manosouri K, Anasti K, Saunders KO, Alam SM, Haynes BF, Acharya P, Henderson R
RgGuinier 5.1 nm
Dmax 18.2 nm
VolumePorod 718 nm3

SASDTY9 – HIV-1 Envelope Glycoprotein SOSIP from a transmitted founder virus of the CH505 isolate at 25 °C

CH505TFchim.6R.SOSIP.664 Env glycoprotein experimental SAS data
CH505TFchim.6R.SOSIP.664 Env glycoprotein Kratky plot
Sample: CH505TFchim.6R.SOSIP.664 Env glycoprotein trimer, 217 kDa HIV-1 group M protein
Buffer: 15 mM HEPES, 150 mM NaCl, pH: 7.1
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2017 Jun 1
Microsecond dynamics control the HIV-1 Envelope conformation. Sci Adv 10(5):eadj0396 (2024)
Bennett AL, Edwards R, Kosheleva I, Saunders C, Bililign Y, Williams A, Bubphamala P, Manosouri K, Anasti K, Saunders KO, Alam SM, Haynes BF, Acharya P, Henderson R
RgGuinier 5.3 nm
Dmax 16.1 nm
VolumePorod 731 nm3