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5 hits found for Brosey

SASDV47 – Peptide-linked fusion protein of Apoptosis-inducing factor 1 AIF(104-613) point mutant W196A and the N-terminal segment of Mitochondrial intermembrane space import and assembly protein 40 CHCHD4(1-45)

Mitochondrial intermembrane space import and assembly protein 40Apoptosis-inducing factor 1, mitochondrial experimental SAS data
Mitochondrial intermembrane space import and assembly protein 40 Apoptosis-inducing factor 1, mitochondrial Kratky plot
Sample: Mitochondrial intermembrane space import and assembly protein 40 dimer, 12 kDa Homo sapiens protein
Apoptosis-inducing factor 1, mitochondrial dimer, 113 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 150 mM NaCl, 2 mM TCEP, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2018 Nov 28
NADH-bound AIF activates the mitochondrial CHCHD4/MIA40 chaperone by a substrate-mimicry mechanism. EMBO J (2025)
Brosey CA, Shen R, Tainer JA
RgGuinier 3.9 nm
Dmax 12.9 nm
VolumePorod 289 nm3

SASDVY6 – Wild-type full-length Mitochondrial intermembrane space import and assembly protein 40 (CHCHD4)

Mitochondrial intermembrane space import and assembly protein 40 experimental SAS data
Mitochondrial intermembrane space import and assembly protein 40 Kratky plot
Sample: Mitochondrial intermembrane space import and assembly protein 40 monomer, 16 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 150 mM NaCl, 2 mM TCEP, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2021 Oct 26
NADH-bound AIF activates the mitochondrial CHCHD4/MIA40 chaperone by a substrate-mimicry mechanism. EMBO J (2025)
Brosey CA, Shen R, Tainer JA
RgGuinier 2.9 nm
Dmax 9.2 nm
VolumePorod 56 nm3

SASDVZ6 – Mitochondrial intermembrane space import and assembly protein 40 (CHCHD4) triple mutant I12A/F14A/H20A (AIA-A)

Mitochondrial intermembrane space import and assembly protein 40 experimental SAS data
Mitochondrial intermembrane space import and assembly protein 40 Kratky plot
Sample: Mitochondrial intermembrane space import and assembly protein 40 monomer, 16 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 150 mM NaCl, 2 mM TCEP, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2021 Oct 26
NADH-bound AIF activates the mitochondrial CHCHD4/MIA40 chaperone by a substrate-mimicry mechanism. EMBO J (2025)
Brosey CA, Shen R, Tainer JA
RgGuinier 3.1 nm
Dmax 10.5 nm
VolumePorod 62 nm3

SASDV27 – Mitochondrial intermembrane space import and assembly protein 40 (CHCHD4) point mutant H20D

Mitochondrial intermembrane space import and assembly protein 40 experimental SAS data
Mitochondrial intermembrane space import and assembly protein 40 Kratky plot
Sample: Mitochondrial intermembrane space import and assembly protein 40 monomer, 16 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 150 mM NaCl, 2 mM TCEP, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2021 Oct 26
NADH-bound AIF activates the mitochondrial CHCHD4/MIA40 chaperone by a substrate-mimicry mechanism. EMBO J (2025)
Brosey CA, Shen R, Tainer JA
RgGuinier 3.2 nm
Dmax 11.2 nm
VolumePorod 66 nm3

SASDV37 – Mitochondrial intermembrane space import and assembly protein 40 (CHCHD4) point mutant L28D

Mitochondrial intermembrane space import and assembly protein 40 experimental SAS data
Mitochondrial intermembrane space import and assembly protein 40 Kratky plot
Sample: Mitochondrial intermembrane space import and assembly protein 40 monomer, 16 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 150 mM NaCl, 2 mM TCEP, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2021 Oct 26
NADH-bound AIF activates the mitochondrial CHCHD4/MIA40 chaperone by a substrate-mimicry mechanism. EMBO J (2025)
Brosey CA, Shen R, Tainer JA
RgGuinier 2.8 nm
Dmax 9.2 nm
VolumePorod 52 nm3