Small Angle Scattering Biological Data Bank SASBDB

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29 hits found for Roche

SASDF93 – Ignicoccus islandicus malate dehydrogenase

Malate dehydrogenase experimental SAS data

Sample:	Malate dehydrogenase tetramer, 134 kDa Ignicoccus islandicus DSM … protein
Buffer:	50 mM Tris-HCl 50 mM NaCl, pH: 7.4
Experiment:	SAXS data collected at BM29, ESRF on 2018 Sep 5

The archaeal LDH-like malate dehydrogenase from Ignicoccus islandicus displays dual substrate recognition, hidden allostery and a non-canonical tetrameric oligomeric organization Journal of Structural Biology (2019)
Roche J, Girard E, Mas C, Madern D

R_g^Guinier	3.3	nm
D_max	9.0	nm
Volume^Porod	198	nm³

SASDTW7 – Heterogeneous nuclear ribonucleoprotein A1-A (hnRNP A1-A; SEC-SAXS, July 2022)

Isoform A1-A of Heterogeneous nuclear ribonucleoprotein A1 (C43S/C175S) experimental SAS data

Isoform A1-A of Heterogeneous nuclear ribonucleoprotein A1 (C43S/C175S) Kratky plot

Sample:	Isoform A1-A of Heterogeneous nuclear ribonucleoprotein A1 (C43S/C175S) monomer, 34 kDa Homo sapiens protein
Buffer:	100 mM HEPES, 350 mM NaCl, 0.5 mM EDTA, pH: 7.5
Experiment:	SAXS data collected at 12-ID-B, Advanced Photon Source (APS), Argonne National Laboratory on 2022 Jul 7

Thermodynamic coupling of the tandem RRM domains of hnRNP A1 underlie its pleiotropic RNA binding functions. Sci Adv 10(28):eadk6580 (2024)
...Roche J, Tolbert BS

R_g^Guinier	2.9	nm
D_max	12.0	nm
Volume^Porod	54	nm³

SASDTX7 – Heterogeneous nuclear ribonucleoprotein A1-A (hnRNP A1-A; SEC-SAXS, Sept 2022)

Sample:	Isoform A1-A of Heterogeneous nuclear ribonucleoprotein A1 (C43S/C175S) monomer, 34 kDa Homo sapiens protein
Buffer:	100 mM HEPES, 350 mM NaCl, 0.5 mM EDTA, pH: 7.5
Experiment:	SAXS data collected at 12-ID-B, Advanced Photon Source (APS), Argonne National Laboratory on 2022 Sep 27

Thermodynamic coupling of the tandem RRM domains of hnRNP A1 underlie its pleiotropic RNA binding functions. Sci Adv 10(28):eadk6580 (2024)
...Roche J, Tolbert BS

R_g^Guinier	2.9	nm
D_max	12.0	nm
Volume^Porod	53	nm³

SASDTY7 – Heterogeneous nuclear ribonucleoprotein A1-A (hnRNP A1-A) at 0.1 MPa

Sample:	Isoform A1-A of Heterogeneous nuclear ribonucleoprotein A1 (C43S/C175S) monomer, 34 kDa Homo sapiens protein
Buffer:	100 mM HEPES, 350 mM NaCl, 0.5 mM EDTA, pH: 7.5
Experiment:	SAXS data collected at G1, Cornell High Energy Synchrotron Source (CHESS) on 2023 Mar 1

Thermodynamic coupling of the tandem RRM domains of hnRNP A1 underlie its pleiotropic RNA binding functions. Sci Adv 10(28):eadk6580 (2024)
...Roche J, Tolbert BS

R_g^Guinier

2.9

SASDTZ7 – Heterogeneous nuclear ribonucleoprotein A1-A (hnRNP A1-A) at 50 MPa

Sample:	Isoform A1-A of Heterogeneous nuclear ribonucleoprotein A1 (C43S/C175S) monomer, 34 kDa Homo sapiens protein
Buffer:	100 mM HEPES, 350 mM NaCl, 0.5 mM EDTA, pH: 7.5
Experiment:	SAXS data collected at G1, Cornell High Energy Synchrotron Source (CHESS) on 2023 Mar 1

Thermodynamic coupling of the tandem RRM domains of hnRNP A1 underlie its pleiotropic RNA binding functions. Sci Adv 10(28):eadk6580 (2024)
...Roche J, Tolbert BS

R_g^Guinier

3.0

SASDT28 – Heterogeneous nuclear ribonucleoprotein A1-A (hnRNP A1-A) at 100 MPa

Sample:	Isoform A1-A of Heterogeneous nuclear ribonucleoprotein A1 (C43S/C175S) monomer, 34 kDa Homo sapiens protein
Buffer:	100 mM HEPES, 350 mM NaCl, 0.5 mM EDTA, pH: 7.5
Experiment:	SAXS data collected at G1, Cornell High Energy Synchrotron Source (CHESS) on 2023 Mar 1

Thermodynamic coupling of the tandem RRM domains of hnRNP A1 underlie its pleiotropic RNA binding functions. Sci Adv 10(28):eadk6580 (2024)
...Roche J, Tolbert BS

R_g^Guinier

3.0

SASDT38 – Heterogeneous nuclear ribonucleoprotein A1-A (hnRNP A1-A) at 150 MPa

Sample:	Isoform A1-A of Heterogeneous nuclear ribonucleoprotein A1 (C43S/C175S) monomer, 34 kDa Homo sapiens protein
Buffer:	100 mM HEPES, 350 mM NaCl, 0.5 mM EDTA, pH: 7.5
Experiment:	SAXS data collected at G1, Cornell High Energy Synchrotron Source (CHESS) on 2023 Mar 1

Thermodynamic coupling of the tandem RRM domains of hnRNP A1 underlie its pleiotropic RNA binding functions. Sci Adv 10(28):eadk6580 (2024)
...Roche J, Tolbert BS

R_g^Guinier

3.3

SASDT48 – Heterogeneous nuclear ribonucleoprotein A1-A (hnRNP A1-A) at 200 MPa

Sample:	Isoform A1-A of Heterogeneous nuclear ribonucleoprotein A1 (C43S/C175S) monomer, 34 kDa Homo sapiens protein
Buffer:	100 mM HEPES, 350 mM NaCl, 0.5 mM EDTA, pH: 7.5
Experiment:	SAXS data collected at G1, Cornell High Energy Synchrotron Source (CHESS) on 2023 Mar 1

Thermodynamic coupling of the tandem RRM domains of hnRNP A1 underlie its pleiotropic RNA binding functions. Sci Adv 10(28):eadk6580 (2024)
...Roche J, Tolbert BS

R_g^Guinier

3.2

SASDT58 – Heterogeneous nuclear ribonucleoprotein A1-A (hnRNP A1-A) at 250 MPa

Sample:	Isoform A1-A of Heterogeneous nuclear ribonucleoprotein A1 (C43S/C175S) monomer, 34 kDa Homo sapiens protein
Buffer:	100 mM HEPES, 350 mM NaCl, 0.5 mM EDTA, pH: 7.5
Experiment:	SAXS data collected at G1, Cornell High Energy Synchrotron Source (CHESS) on 2023 Mar 1

Thermodynamic coupling of the tandem RRM domains of hnRNP A1 underlie its pleiotropic RNA binding functions. Sci Adv 10(28):eadk6580 (2024)
...Roche J, Tolbert BS

R_g^Guinier

3.3

SASDT68 – UP1 domain of heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) at 0.1 MPa

Heterogeneous nuclear ribonucleoprotein A1 experimental SAS data

Heterogeneous nuclear ribonucleoprotein A1 Kratky plot

Sample:	Heterogeneous nuclear ribonucleoprotein A1 monomer, 25 kDa Homo sapiens protein
Buffer:	100 mM HEPES, 350 mM NaCl, 0.5 mM EDTA, pH: 7.5
Experiment:	SAXS data collected at G1, Cornell High Energy Synchrotron Source (CHESS) on 2023 Mar 1

Thermodynamic coupling of the tandem RRM domains of hnRNP A1 underlie its pleiotropic RNA binding functions. Sci Adv 10(28):eadk6580 (2024)
...Roche J, Tolbert BS

R_g^Guinier	2.6	nm
D_max	13.0	nm
Volume^Porod	36	nm³

SASDT78 – UP1 domain of heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) at 50 MPa

Sample:	Heterogeneous nuclear ribonucleoprotein A1 monomer, 25 kDa Homo sapiens protein
Buffer:	100 mM HEPES, 350 mM NaCl, 0.5 mM EDTA, pH: 7.5
Experiment:	SAXS data collected at G1, Cornell High Energy Synchrotron Source (CHESS) on 2023 Mar 1

Thermodynamic coupling of the tandem RRM domains of hnRNP A1 underlie its pleiotropic RNA binding functions. Sci Adv 10(28):eadk6580 (2024)
...Roche J, Tolbert BS

R_g^Guinier	2.6	nm
D_max	11.0	nm
Volume^Porod	33	nm³

SASDT88 – UP1 domain of heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) at 100 MPa

Sample:	Heterogeneous nuclear ribonucleoprotein A1 monomer, 25 kDa Homo sapiens protein
Buffer:	100 mM HEPES, 350 mM NaCl, 0.5 mM EDTA, pH: 7.5
Experiment:	SAXS data collected at G1, Cornell High Energy Synchrotron Source (CHESS) on 2023 Mar 1

Thermodynamic coupling of the tandem RRM domains of hnRNP A1 underlie its pleiotropic RNA binding functions. Sci Adv 10(28):eadk6580 (2024)
...Roche J, Tolbert BS

R_g^Guinier	2.5	nm
D_max	10.0	nm
Volume^Porod	32	nm³

SASDT98 – UP1 domain of heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) at 150 MPa

Sample:	Heterogeneous nuclear ribonucleoprotein A1 monomer, 25 kDa Homo sapiens protein
Buffer:	100 mM HEPES, 350 mM NaCl, 0.5 mM EDTA, pH: 7.5
Experiment:	SAXS data collected at G1, Cornell High Energy Synchrotron Source (CHESS) on 2023 Mar 1

Thermodynamic coupling of the tandem RRM domains of hnRNP A1 underlie its pleiotropic RNA binding functions. Sci Adv 10(28):eadk6580 (2024)
...Roche J, Tolbert BS

R_g^Guinier	2.4	nm
D_max	10.0	nm
Volume^Porod	29	nm³

SASDTA8 – UP1 domain of heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) at 200 MPa

Sample:	Heterogeneous nuclear ribonucleoprotein A1 monomer, 25 kDa Homo sapiens protein
Buffer:	100 mM HEPES, 350 mM NaCl, 0.5 mM EDTA, pH: 7.5
Experiment:	SAXS data collected at G1, Cornell High Energy Synchrotron Source (CHESS) on 2023 Mar 1

Thermodynamic coupling of the tandem RRM domains of hnRNP A1 underlie its pleiotropic RNA binding functions. Sci Adv 10(28):eadk6580 (2024)
...Roche J, Tolbert BS

R_g^Guinier	2.4	nm
D_max	9.5	nm
Volume^Porod	28	nm³

SASDTB8 – UP1 domain of heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) at 250 MPa

Sample:	Heterogeneous nuclear ribonucleoprotein A1 monomer, 25 kDa Homo sapiens protein
Buffer:	100 mM HEPES, 350 mM NaCl, 0.5 mM EDTA, pH: 7.5
Experiment:	SAXS data collected at G1, Cornell High Energy Synchrotron Source (CHESS) on 2023 Mar 1

Thermodynamic coupling of the tandem RRM domains of hnRNP A1 underlie its pleiotropic RNA binding functions. Sci Adv 10(28):eadk6580 (2024)
...Roche J, Tolbert BS

R_g^Guinier	2.4	nm
D_max	9.5	nm
Volume^Porod	29	nm³

SASDTC8 – Heterogeneous nuclear ribonucleoprotein A1-A mutant (hnRNP A1-A(mut); SEC-SAXS, July 2022)

Isoform A1-A of Heterogeneous nuclear ribonucleoprotein A1 (C43S/R75D/R88D/C175S ) experimental SAS data

Isoform A1-A of Heterogeneous nuclear ribonucleoprotein A1 (C43S/R75D/R88D/C175S ) Kratky plot

Sample:	Isoform A1-A of Heterogeneous nuclear ribonucleoprotein A1 (C43S/R75D/R88D/C175S ) monomer, 34 kDa Homo sapiens protein
Buffer:	100 mM HEPES, 350 mM NaCl, 0.5 mM EDTA, pH: 7.5
Experiment:	SAXS data collected at 12-ID-B, Advanced Photon Source (APS), Argonne National Laboratory on 2022 Jul 7

Thermodynamic coupling of the tandem RRM domains of hnRNP A1 underlie its pleiotropic RNA binding functions. Sci Adv 10(28):eadk6580 (2024)
...Roche J, Tolbert BS

R_g^Guinier	3.4	nm
D_max	14.0	nm
Volume^Porod	57	nm³

SASDTD8 – Heterogeneous nuclear ribonucleoprotein A1-A mutant (hnRNP A1-A(mut); SEC-SAXS, Sept 2022)

Sample:	Isoform A1-A of Heterogeneous nuclear ribonucleoprotein A1 (C43S/R75D/R88D/C175S ) monomer, 34 kDa Homo sapiens protein
Buffer:	100 mM HEPES, 350 mM NaCl, 0.5 mM EDTA, pH: 7.5
Experiment:	SAXS data collected at 12-ID-B, Advanced Photon Source (APS), Argonne National Laboratory on 2022 Sep 27

Thermodynamic coupling of the tandem RRM domains of hnRNP A1 underlie its pleiotropic RNA binding functions. Sci Adv 10(28):eadk6580 (2024)
...Roche J, Tolbert BS

R_g^Guinier	3.7	nm
D_max	14.0	nm
Volume^Porod	58	nm³

SASDTE8 – Heterogeneous nuclear ribonucleoprotein A1-A mutant (hnRNP A1-A(mut)) at 0.1 MPa

Sample:	Isoform A1-A of Heterogeneous nuclear ribonucleoprotein A1 (C43S/R75D/R88D/C175S ) monomer, 34 kDa Homo sapiens protein
Buffer:	100 mM HEPES, 350 mM NaCl, 0.5 mM EDTA, pH: 7.5
Experiment:	SAXS data collected at G1, Cornell High Energy Synchrotron Source (CHESS) on 2023 Mar 1

Thermodynamic coupling of the tandem RRM domains of hnRNP A1 underlie its pleiotropic RNA binding functions. Sci Adv 10(28):eadk6580 (2024)
...Roche J, Tolbert BS

R_g^Guinier	3.6	nm
D_max	20.0	nm
Volume^Porod	98	nm³

SASDTF8 – Heterogeneous nuclear ribonucleoprotein A1-A mutant (hnRNP A1-A(mut)) at 50 MPa

Sample:	Isoform A1-A of Heterogeneous nuclear ribonucleoprotein A1 (C43S/R75D/R88D/C175S ) monomer, 34 kDa Homo sapiens protein
Buffer:	100 mM HEPES, 350 mM NaCl, 0.5 mM EDTA, pH: 7.5
Experiment:	SAXS data collected at G1, Cornell High Energy Synchrotron Source (CHESS) on 2023 Mar 1

Thermodynamic coupling of the tandem RRM domains of hnRNP A1 underlie its pleiotropic RNA binding functions. Sci Adv 10(28):eadk6580 (2024)
...Roche J, Tolbert BS

R_g^Guinier	3.7	nm
D_max	23.0	nm
Volume^Porod	104	nm³

SASDTG8 – Heterogeneous nuclear ribonucleoprotein A1-A mutant (hnRNP A1-A(mut)) at 100 MPa

Sample:	Isoform A1-A of Heterogeneous nuclear ribonucleoprotein A1 (C43S/R75D/R88D/C175S ) monomer, 34 kDa Homo sapiens protein
Buffer:	100 mM HEPES, 350 mM NaCl, 0.5 mM EDTA, pH: 7.5
Experiment:	SAXS data collected at G1, Cornell High Energy Synchrotron Source (CHESS) on 2023 Mar 1

Thermodynamic coupling of the tandem RRM domains of hnRNP A1 underlie its pleiotropic RNA binding functions. Sci Adv 10(28):eadk6580 (2024)
...Roche J, Tolbert BS

R_g^Guinier	3.6	nm
D_max	23.0	nm
Volume^Porod	94	nm³

SASDTH8 – Heterogeneous nuclear ribonucleoprotein A1-A mutant (hnRNP A1-A(mut)) at 150 MPa

Sample:	Isoform A1-A of Heterogeneous nuclear ribonucleoprotein A1 (C43S/R75D/R88D/C175S ) monomer, 34 kDa Homo sapiens protein
Buffer:	100 mM HEPES, 350 mM NaCl, 0.5 mM EDTA, pH: 7.5
Experiment:	SAXS data collected at G1, Cornell High Energy Synchrotron Source (CHESS) on 2023 Mar 1

Thermodynamic coupling of the tandem RRM domains of hnRNP A1 underlie its pleiotropic RNA binding functions. Sci Adv 10(28):eadk6580 (2024)
...Roche J, Tolbert BS

R_g^Guinier	3.6	nm
D_max	23.0	nm
Volume^Porod	109	nm³

SASDTJ8 – Heterogeneous nuclear ribonucleoprotein A1-A mutant (hnRNP A1-A(mut)) at 200 MPa

Sample:	Isoform A1-A of Heterogeneous nuclear ribonucleoprotein A1 (C43S/R75D/R88D/C175S ) monomer, 34 kDa Homo sapiens protein
Buffer:	100 mM HEPES, 350 mM NaCl, 0.5 mM EDTA, pH: 7.5
Experiment:	SAXS data collected at G1, Cornell High Energy Synchrotron Source (CHESS) on 2023 Mar 1

Thermodynamic coupling of the tandem RRM domains of hnRNP A1 underlie its pleiotropic RNA binding functions. Sci Adv 10(28):eadk6580 (2024)
...Roche J, Tolbert BS

R_g^Guinier

3.7

SASDTK8 – Heterogeneous nuclear ribonucleoprotein A1-A mutant (hnRNP A1-A(mut)) at 250 MPa

Sample:	Isoform A1-A of Heterogeneous nuclear ribonucleoprotein A1 (C43S/R75D/R88D/C175S ) monomer, 34 kDa Homo sapiens protein
Buffer:	100 mM HEPES, 350 mM NaCl, 0.5 mM EDTA, pH: 7.5
Experiment:	SAXS data collected at G1, Cornell High Energy Synchrotron Source (CHESS) on 2023 Mar 1

Thermodynamic coupling of the tandem RRM domains of hnRNP A1 underlie its pleiotropic RNA binding functions. Sci Adv 10(28):eadk6580 (2024)
...Roche J, Tolbert BS

R_g^Guinier

3.6

SASDTL8 – UP1 domain mutant of heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) at 0.1 MPa

Heterogeneous nuclear ribonucleoprotein A1 (C43S/R75D/R88D/C175S ) experimental SAS data

Heterogeneous nuclear ribonucleoprotein A1 (C43S/R75D/R88D/C175S ) Kratky plot

Sample:	Heterogeneous nuclear ribonucleoprotein A1 (C43S/R75D/R88D/C175S ) monomer, 25 kDa Homo sapiens protein
Buffer:	100 mM HEPES, 350 mM NaCl, 0.5 mM EDTA, pH: 7.5
Experiment:	SAXS data collected at G1, Cornell High Energy Synchrotron Source (CHESS) on 2023 Mar 1

Thermodynamic coupling of the tandem RRM domains of hnRNP A1 underlie its pleiotropic RNA binding functions. Sci Adv 10(28):eadk6580 (2024)
...Roche J, Tolbert BS

R_g^Guinier

2.8

SASDTM8 – UP1 domain mutant of heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) at 50 MPa

Sample:	Heterogeneous nuclear ribonucleoprotein A1 (C43S/R75D/R88D/C175S ) monomer, 25 kDa Homo sapiens protein
Buffer:	100 mM HEPES, 350 mM NaCl, 0.5 mM EDTA, pH: 7.5
Experiment:	SAXS data collected at G1, Cornell High Energy Synchrotron Source (CHESS) on 2023 Mar 1

Thermodynamic coupling of the tandem RRM domains of hnRNP A1 underlie its pleiotropic RNA binding functions. Sci Adv 10(28):eadk6580 (2024)
...Roche J, Tolbert BS

R_g^Guinier

3.0

SASDTN8 – UP1 domain mutant of heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) at 100 MPa

Sample:	Heterogeneous nuclear ribonucleoprotein A1 (C43S/R75D/R88D/C175S ) monomer, 25 kDa Homo sapiens protein
Buffer:	100 mM HEPES, 350 mM NaCl, 0.5 mM EDTA, pH: 7.5
Experiment:	SAXS data collected at G1, Cornell High Energy Synchrotron Source (CHESS) on 2023 Mar 1

Thermodynamic coupling of the tandem RRM domains of hnRNP A1 underlie its pleiotropic RNA binding functions. Sci Adv 10(28):eadk6580 (2024)
...Roche J, Tolbert BS

R_g^Guinier

3.2

SASDTP8 – UP1 domain mutant of heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) at 150 MPa

Sample:	Heterogeneous nuclear ribonucleoprotein A1 (C43S/R75D/R88D/C175S ) monomer, 25 kDa Homo sapiens protein
Buffer:	100 mM HEPES, 350 mM NaCl, 0.5 mM EDTA, pH: 7.5
Experiment:	SAXS data collected at G1, Cornell High Energy Synchrotron Source (CHESS) on 2023 Mar 1

Thermodynamic coupling of the tandem RRM domains of hnRNP A1 underlie its pleiotropic RNA binding functions. Sci Adv 10(28):eadk6580 (2024)
...Roche J, Tolbert BS

R_g^Guinier

2.9

SASDTQ8 – UP1 domain mutant of heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) at 200 MPa

Sample:	Heterogeneous nuclear ribonucleoprotein A1 (C43S/R75D/R88D/C175S ) monomer, 25 kDa Homo sapiens protein
Buffer:	100 mM HEPES, 350 mM NaCl, 0.5 mM EDTA, pH: 7.5
Experiment:	SAXS data collected at G1, Cornell High Energy Synchrotron Source (CHESS) on 2023 Mar 1

Thermodynamic coupling of the tandem RRM domains of hnRNP A1 underlie its pleiotropic RNA binding functions. Sci Adv 10(28):eadk6580 (2024)
...Roche J, Tolbert BS

R_g^Guinier

3.1

SASDTR8 – UP1 domain mutant of heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) at 250 MPa

Sample:	Heterogeneous nuclear ribonucleoprotein A1 (C43S/R75D/R88D/C175S ) monomer, 25 kDa Homo sapiens protein
Buffer:	100 mM HEPES, 350 mM NaCl, 0.5 mM EDTA, pH: 7.5
Experiment:	SAXS data collected at G1, Cornell High Energy Synchrotron Source (CHESS) on 2023 Mar 1

Thermodynamic coupling of the tandem RRM domains of hnRNP A1 underlie its pleiotropic RNA binding functions. Sci Adv 10(28):eadk6580 (2024)
...Roche J, Tolbert BS

R_g^Guinier

3.2