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14 hits found for Zeronian

SASDJ38 – Monomeric Jagged1 high-affinity full ectodomain

Protein jagged-1 experimental SAS data
Protein jagged-1 Kratky plot
Sample: Protein jagged-1 monomer, 115 kDa Mus musculus protein
Buffer: 20 mM HEPES, 150 mM NaCl, 2 mM CaCl2, pH: 7.4
Experiment: SAXS data collected at B21, Diamond Light Source on 2018 Dec 12
Notch-Jagged signaling complex defined by an interaction mosaic. Proc Natl Acad Sci U S A 118(30) (2021)
Zeronian MR, Klykov O, Portell I de Montserrat J, Konijnenberg MJ, Gaur A, Scheltema RA, Janssen BJC
RgGuinier 7.4 nm
Dmax 24.0 nm
VolumePorod 375 nm3

SASDJ48 – Jagged1 high-affinity full ectodomain 5.3 µM

Protein jagged-1 experimental SAS data
Protein jagged-1 Kratky plot
Sample: Protein jagged-1 , 115 kDa Mus musculus protein
Buffer: 20 mM HEPES, 150 mM NaCl, 2 mM CaCl2, pH: 7.4
Experiment: SAXS data collected at B21, Diamond Light Source on 2018 Dec 11
Notch-Jagged signaling complex defined by an interaction mosaic. Proc Natl Acad Sci U S A 118(30) (2021)
Zeronian MR, Klykov O, Portell I de Montserrat J, Konijnenberg MJ, Gaur A, Scheltema RA, Janssen BJC
RgGuinier 8.1 nm
Dmax 30.0 nm
VolumePorod 430 nm3

SASDJ58 – Jagged1 high-affinity full ectodomain 11 µM

Protein jagged-1 experimental SAS data
Protein jagged-1 Kratky plot
Sample: Protein jagged-1 , 115 kDa Mus musculus protein
Buffer: 20 mM HEPES, 150 mM NaCl, 2 mM CaCl2, pH: 7.4
Experiment: SAXS data collected at B21, Diamond Light Source on 2018 Dec 11
Notch-Jagged signaling complex defined by an interaction mosaic. Proc Natl Acad Sci U S A 118(30) (2021)
Zeronian MR, Klykov O, Portell I de Montserrat J, Konijnenberg MJ, Gaur A, Scheltema RA, Janssen BJC
RgGuinier 8.9 nm
Dmax 33.0 nm
VolumePorod 505 nm3

SASDJ68 – Jagged1 high-affinity full ectodomain 21 µM

Protein jagged-1 experimental SAS data
Protein jagged-1 Kratky plot
Sample: Protein jagged-1 , 115 kDa Mus musculus protein
Buffer: 20 mM HEPES, 150 mM NaCl, 2 mM CaCl2, pH: 7.4
Experiment: SAXS data collected at B21, Diamond Light Source on 2018 Dec 11
Notch-Jagged signaling complex defined by an interaction mosaic. Proc Natl Acad Sci U S A 118(30) (2021)
Zeronian MR, Klykov O, Portell I de Montserrat J, Konijnenberg MJ, Gaur A, Scheltema RA, Janssen BJC
RgGuinier 9.6 nm
Dmax 42.0 nm
VolumePorod 715 nm3

SASDJ78 – Jagged1 high-affinity full ectodomain 42 µM

Protein jagged-1 experimental SAS data
Protein jagged-1 Kratky plot
Sample: Protein jagged-1 , 115 kDa Mus musculus protein
Buffer: 20 mM HEPES, 150 mM NaCl, 2 mM CaCl2, pH: 7.4
Experiment: SAXS data collected at B21, Diamond Light Source on 2018 Dec 11
Notch-Jagged signaling complex defined by an interaction mosaic. Proc Natl Acad Sci U S A 118(30) (2021)
Zeronian MR, Klykov O, Portell I de Montserrat J, Konijnenberg MJ, Gaur A, Scheltema RA, Janssen BJC
RgGuinier 10.2 nm
Dmax 43.0 nm
VolumePorod 900 nm3

SASDJ88 – Jagged1 EGF8-11 29 µM

Protein jagged-1 EGF8-11 experimental SAS data
Protein jagged-1 EGF8-11 Kratky plot
Sample: Protein jagged-1 EGF8-11 , 21 kDa Mus musculus protein
Buffer: 20 mM HEPES, 150 mM NaCl, 2 mM CaCl2, pH: 7.4
Experiment: SAXS data collected at B21, Diamond Light Source on 2018 Dec 11
Notch-Jagged signaling complex defined by an interaction mosaic. Proc Natl Acad Sci U S A 118(30) (2021)
Zeronian MR, Klykov O, Portell I de Montserrat J, Konijnenberg MJ, Gaur A, Scheltema RA, Janssen BJC
RgGuinier 3.3 nm
Dmax 11.0 nm
VolumePorod 26 nm3

SASDJ98 – Jagged1 EGF8-11 58 µM

Protein jagged-1 EGF8-11 experimental SAS data
Protein jagged-1 EGF8-11 Kratky plot
Sample: Protein jagged-1 EGF8-11 , 21 kDa Mus musculus protein
Buffer: 20 mM HEPES, 150 mM NaCl, 2 mM CaCl2, pH: 7.4
Experiment: SAXS data collected at B21, Diamond Light Source on 2018 Dec 11
Notch-Jagged signaling complex defined by an interaction mosaic. Proc Natl Acad Sci U S A 118(30) (2021)
Zeronian MR, Klykov O, Portell I de Montserrat J, Konijnenberg MJ, Gaur A, Scheltema RA, Janssen BJC
RgGuinier 3.2 nm
Dmax 11.5 nm
VolumePorod 31 nm3

SASDJA8 – Jagged1 EGF8-11 115 µM

Protein jagged-1 EGF8-11 experimental SAS data
Protein jagged-1 EGF8-11 Kratky plot
Sample: Protein jagged-1 EGF8-11 , 21 kDa Mus musculus protein
Buffer: 20 mM HEPES, 150 mM NaCl, 2 mM CaCl2, pH: 7.4
Experiment: SAXS data collected at B21, Diamond Light Source on 2018 Dec 11
Notch-Jagged signaling complex defined by an interaction mosaic. Proc Natl Acad Sci U S A 118(30) (2021)
Zeronian MR, Klykov O, Portell I de Montserrat J, Konijnenberg MJ, Gaur A, Scheltema RA, Janssen BJC
RgGuinier 3.1 nm
Dmax 11.5 nm
VolumePorod 34 nm3

SASDJB8 – Jagged1 EGF8-11 230 µM

Protein jagged-1 EGF8-11 experimental SAS data
Protein jagged-1 EGF8-11 Kratky plot
Sample: Protein jagged-1 EGF8-11 , 21 kDa Mus musculus protein
Buffer: 20 mM HEPES, 150 mM NaCl, 2 mM CaCl2, pH: 7.4
Experiment: SAXS data collected at B21, Diamond Light Source on 2018 Dec 11
Notch-Jagged signaling complex defined by an interaction mosaic. Proc Natl Acad Sci U S A 118(30) (2021)
Zeronian MR, Klykov O, Portell I de Montserrat J, Konijnenberg MJ, Gaur A, Scheltema RA, Janssen BJC
RgGuinier 3.2 nm
Dmax 12.0 nm
VolumePorod 66 nm3

SASDJC8 – Jagged1 cysteine-rich domain (CRD) 21 µM

Protein jagged-1 cysteine-rich domain experimental SAS data
Protein jagged-1 cysteine-rich domain Kratky plot
Sample: Protein jagged-1 cysteine-rich domain , 24 kDa Mus musculus protein
Buffer: 20 mM HEPES, 150 mM NaCl, 2 mM CaCl2, pH: 7.4
Experiment: SAXS data collected at B21, Diamond Light Source on 2018 Dec 11
Notch-Jagged signaling complex defined by an interaction mosaic. Proc Natl Acad Sci U S A 118(30) (2021)
Zeronian MR, Klykov O, Portell I de Montserrat J, Konijnenberg MJ, Gaur A, Scheltema RA, Janssen BJC
RgGuinier 2.3 nm
Dmax 7.5 nm
VolumePorod 51 nm3

SASDJD8 – Jagged1 cysteine-rich domain (CRD) 42 µM

Protein jagged-1 cysteine-rich domain experimental SAS data
Protein jagged-1 cysteine-rich domain Kratky plot
Sample: Protein jagged-1 cysteine-rich domain , 24 kDa Mus musculus protein
Buffer: 20 mM HEPES, 150 mM NaCl, 2 mM CaCl2, pH: 7.4
Experiment: SAXS data collected at B21, Diamond Light Source on 2018 Dec 11
Notch-Jagged signaling complex defined by an interaction mosaic. Proc Natl Acad Sci U S A 118(30) (2021)
Zeronian MR, Klykov O, Portell I de Montserrat J, Konijnenberg MJ, Gaur A, Scheltema RA, Janssen BJC
RgGuinier 2.3 nm
Dmax 7.8 nm
VolumePorod 56 nm3

SASDJE8 – Jagged1 cysteine-rich domain (CRD) 83 µM

Protein jagged-1 cysteine-rich domain experimental SAS data
Protein jagged-1 cysteine-rich domain Kratky plot
Sample: Protein jagged-1 cysteine-rich domain , 24 kDa Mus musculus protein
Buffer: 20 mM HEPES, 150 mM NaCl, 2 mM CaCl2, pH: 7.4
Experiment: SAXS data collected at B21, Diamond Light Source on 2018 Dec 11
Notch-Jagged signaling complex defined by an interaction mosaic. Proc Natl Acad Sci U S A 118(30) (2021)
Zeronian MR, Klykov O, Portell I de Montserrat J, Konijnenberg MJ, Gaur A, Scheltema RA, Janssen BJC
RgGuinier 2.3 nm
Dmax 8.2 nm
VolumePorod 59 nm3

SASDJF8 – Jagged1 cysteine-rich domain (CRD) 167 µM

Protein jagged-1 cysteine-rich domain experimental SAS data
Protein jagged-1 cysteine-rich domain Kratky plot
Sample: Protein jagged-1 cysteine-rich domain , 24 kDa Mus musculus protein
Buffer: 20 mM HEPES, 150 mM NaCl, 2 mM CaCl2, pH: 7.4
Experiment: SAXS data collected at B21, Diamond Light Source on 2018 Dec 11
Notch-Jagged signaling complex defined by an interaction mosaic. Proc Natl Acad Sci U S A 118(30) (2021)
Zeronian MR, Klykov O, Portell I de Montserrat J, Konijnenberg MJ, Gaur A, Scheltema RA, Janssen BJC
RgGuinier 2.4 nm
Dmax 9.0 nm
VolumePorod 61 nm3

SASDJG8 – Monomeric neurogenic locus notch homolog protein 1 (Notch1) full ectodomain

Neurogenic locus notch homolog protein 1 full ectodomain experimental SAS data
Neurogenic locus notch homolog protein 1 full ectodomain Kratky plot
Sample: Neurogenic locus notch homolog protein 1 full ectodomain monomer, 183 kDa Homo sapiens protein
Buffer: 20 mM HEPES, 150 mM NaCl, 2 mM CaCl2, pH: 7.4
Experiment: SAXS data collected at BM29, ESRF on 2018 Jul 25
Notch-Jagged signaling complex defined by an interaction mosaic. Proc Natl Acad Sci U S A 118(30) (2021)
Zeronian MR, Klykov O, Portell I de Montserrat J, Konijnenberg MJ, Gaur A, Scheltema RA, Janssen BJC
RgGuinier 10.5 nm
Dmax 38.0 nm
VolumePorod 1000 nm3