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3 hits found for 3-phosphoinositide-dependent protein kinase 1

SASDNJ5 – ...3-phosphoinositide-dependent protein kinase (PDK1)

3-phosphoinositide-dependent protein kinase 1 experimental SAS data
DAMMIF model
Sample: 3-phosphoinositide-dependent protein kinase 1 monomer, 65 kDa Homo sapiens protein
Buffer: ...1 mM DTT, pH: 7.4
Experiment: SAXS data collected at ...12, PETRA III on ...1 Mar 26
...kinase PDK1 by distinct conformations of the full-length protein Science Signaling 16(789) (2023)
Sacerdoti M, Gross L, Riley A, Zehnder K, Ghode A, Klinke S, Anand G, Paris K, Winkel A, Herbrand A, Godage H, Cozier G, Süß E, Schulze J, Pastor-Flores D, Bollini M, Cappellari M, Svergun D, Gräwert ...
RgGuinier 3.5 nm
Dmax 11.2 nm
VolumePorod 107 nm3

SASDNK5 – ...3-phosphoinositide-dependent protein kinase (PDK1) in the presence of HYG8 (2-O-benzoyl-Ins(1,3,4,5,6)P5)

3-phosphoinositide-dependent protein kinase 12-O-benzoyl-Ins(1,3,4,5,6)P5 experimental SAS data
DAMMIF model
Sample: 3-phosphoinositide-dependent protein kinase 1 monomer, 65 kDa Homo sapiens protein
...1,3,4,5,6)P5 monomer, 1 kDa synthetic construct
Buffer: ...1 mM DTT, 1 μM HYG8, pH: 7.4
Experiment: SAXS data collected at ...12, PETRA III on ...1 Mar 26
...kinase PDK1 by distinct conformations of the full-length protein Science Signaling 16(789) (2023)
Sacerdoti M, Gross L, Riley A, Zehnder K, Ghode A, Klinke S, Anand G, Paris K, Winkel A, Herbrand A, Godage H, Cozier G, Süß E, Schulze J, Pastor-Flores D, Bollini M, Cappellari M, Svergun D, Gräwert ...
RgGuinier 3.5 nm
Dmax 11.5 nm
VolumePorod 98 nm3

SASDNL5 – ...3-phosphoinositide-dependent protein kinase 1 (PDK1 50–359; Y188G Q292A)

3-phosphoinositide-dependent protein kinase 1 (Y188G Q292A) experimental SAS data
SREFLEX model
Sample: 3-phosphoinositide-dependent protein kinase 1 (Y188G Q292A) monomer, 35 kDa Homo sapiens protein
Buffer: ...1 mM DTT, pH: 7.4
Experiment: SAXS data collected at ...12, PETRA III on ...1 Mar 26
...kinase PDK1 by distinct conformations of the full-length protein Science Signaling 16(789) (2023)
Sacerdoti M, Gross L, Riley A, Zehnder K, Ghode A, Klinke S, Anand G, Paris K, Winkel A, Herbrand A, Godage H, Cozier G, Süß E, Schulze J, Pastor-Flores D, Bollini M, Cappellari M, Svergun D, Gräwert ...
RgGuinier 2.4 nm
Dmax 7.0 nm
VolumePorod 57 nm3