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3 hits found for Calcium/calmodulin-dependent protein kinase kinase 2

SASDSQ7Calcium/calmodulin-dependent protein kinase kinase 2 (CaMKK2)

Calcium/calmodulin-dependent protein kinase kinase 2 experimental SAS data
MULTIFOXS model
Sample: Calcium/calmodulin-dependent protein kinase kinase 2 monomer, 48 kDa Homo sapiens protein
Buffer: 50 mM Tris-HCl, 150 mM NaCl, 1 mM TCEP, 3% (w/v) glycerol, pH: 7.5
Experiment: SAXS data collected at ...2, PETRA III on 2019 Oct 3
...protein inhibits CaMKK1 by blocking the kinase active site with its last two C-terminal helices. Protein Sci :e4805 (2023)
Petrvalska O, Honzejkova K, Koupilova N, Herman P, Obsilova V, Obsil T
RgGuinier 3.2 nm
Dmax 13.3 nm
VolumePorod 91 nm3

SASDST8 – ...Calcium/calmodulin-dependent protein kinase 2 (pCaMKK2)

Calcium/calmodulin-dependent protein kinase kinase 2 experimental SAS data
Calcium/calmodulin-dependent protein kinase kinase 2 Kratky plot
Sample: Calcium/calmodulin-dependent protein kinase kinase 2 monomer, 48 kDa Homo sapiens protein
Buffer: 50 mM Tris-HCl, 150 mM NaCl, 1 mM TCEP, 3% (w/v) glycerol, pH: 7.5
Experiment: SAXS data collected at ...2, PETRA III on 2023 Aug 17
...protein inhibits CaMKK1 by blocking the kinase active site with its last two C-terminal helices. Protein Sci :e4805 (2023)
Petrvalska O, Honzejkova K, Koupilova N, Herman P, Obsilova V, Obsil T
RgGuinier 3.0 nm
Dmax 12.0 nm
VolumePorod 87 nm3

SASDSX7 – ...2 bound to 14-3-3 gamma

14-3-3 protein gammaCalcium/calmodulin-dependent protein kinase kinase 2 experimental SAS data
ALLOSMOD model
Sample: ...protein gamma dimer, 54 kDa Homo sapiens protein
Calcium/calmodulin-dependent protein kinase kinase 2 monomer, 48 kDa Homo sapiens protein
Buffer: 50 mM Tris-HCl, 150 mM NaCl, 1 mM TCEP, 3% (w/v) glycerol, pH: 7.5
Experiment: SAXS data collected at ...2, PETRA III on 2021 Oct 23
...protein inhibits CaMKK1 by blocking the kinase active site with its last two C-terminal helices. Protein Sci :e4805 (2023)
Petrvalska O, Honzejkova K, Koupilova N, Herman P, Obsilova V, Obsil T
RgGuinier 3.7 nm
Dmax 13.2 nm
VolumePorod 157 nm3