2 hits found for FcRn binding optimised human serum albumin V418M, T420A, E505G, V547A

SASDF22 – ...FcRn ectodomain, FcRn binding optimised human serum albumin and the human growth hormone derivative somapacitan. Sample: somapacitan monomer, 22 kDa Homo sapiens protein FcRn binding optimised human serum albumin V418M, T420A, E505G, V547A monomer, 66 kDa Homo sapiens protein neonatal Fc receptor ectodomain beta-microglogulin part with C-terminal His6 tag monomer, 13 kDa Homo sapiens protein neonatal Fc receptor ectodomain alpha-chain monomer, 30 kDa Homo sapiens protein Buffer: 100 mM MES, 100 mM NaCl, pH: 6.5 Experiment: SAXS data collected at I911-4, MAX IV on 2015 May 11 ...binding sites on human serum albumin for somapacitan - a long-acting growth hormone derivative. Biochemistry (2020) Johansson E, Nielsen AD, Demuth H, Wiberg C, Schjødt C, Huang T, Chen J, Jensen S, Petersen J, Thygesen P RgGuinier 4.2 nm Dmax 14.7 nm VolumePorod 227 nm3

SASDF32 – ...FcRn ectodomain, FcRn binding optimised human serum albumin and the albumin-binding side chain of the human growth hormone derivative somapacitan. Sample: FcRn binding optimised human serum albumin V418M, T420A, E505G, V547A monomer, 66 kDa Homo sapiens protein neonatal Fc receptor ectodomain beta-microglogulin part with C-terminal His6 tag monomer, 13 kDa Homo sapiens protein Albumin-binding side-chain monomer, 1 kDa neonatal Fc receptor ectodomain alpha-chain monomer, 30 kDa Homo sapiens protein Buffer: 100 mM MES, 100 mM NaCl, pH: 6.5 Experiment: SAXS data collected at I911-4, MAX IV on 2015 Nov 11 ...binding sites on human serum albumin for somapacitan - a long-acting growth hormone derivative. Biochemistry (2020) Johansson E, Nielsen AD, Demuth H, Wiberg C, Schjødt C, Huang T, Chen J, Jensen S, Petersen J, Thygesen P RgGuinier 3.6 nm Dmax 12.6 nm VolumePorod 174 nm3