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8
hits found for
Isoform A1-A of Heterogeneous nuclear ribonucleoprotein A1 (C43S/R75D/R88D/C175S )
SASDTC8
–
Heterogeneous
nuclear
ribonucleoprotein
A1
-A mutant (hnRNP
A1
-A(mut
)
; SEC-SAXS, July 2022
)
Sample:
Isoform
A1
-A
of
Heterogeneous
nuclear
ribonucleoprotein
A1
(C43S/R75D/R88D/C175S
)
monomer, 34 kDa
Homo sapiens
protein
Buffer:
100 mM HEPES, 350 mM NaCl, 0.5 mM EDTA, pH: 7.5
Experiment:
SAXS data collected at 12-ID-B, ...
)
, Argonne National Laboratory
on 2022 Jul 7
...
of
the tandem RRM domains
of
hnRNP
A1
underlie its pleiotropic RNA binding functions.
Sci Adv
10(28):eadk6580 (2024)
Levengood JD, Potoyan D, Penumutchu S, Kumar A, Zhou Q, Wang Y, Hansen AL, Kutluay S, Roche J, Tolbert BS
R
g
Guinier
3.4
nm
D
max
14.0
nm
Volume
Porod
57
nm
3
SASDTD8
–
Heterogeneous
nuclear
ribonucleoprotein
A1
-A mutant (hnRNP
A1
-A(mut
)
; SEC-SAXS, Sept 2022
)
Sample:
Isoform
A1
-A
of
Heterogeneous
nuclear
ribonucleoprotein
A1
(C43S/R75D/R88D/C175S
)
monomer, 34 kDa
Homo sapiens
protein
Buffer:
100 mM HEPES, 350 mM NaCl, 0.5 mM EDTA, pH: 7.5
Experiment:
SAXS data collected at 12-ID-B, ...
)
, Argonne National Laboratory
on 2022 Sep 27
...
of
the tandem RRM domains
of
hnRNP
A1
underlie its pleiotropic RNA binding functions.
Sci Adv
10(28):eadk6580 (2024)
Levengood JD, Potoyan D, Penumutchu S, Kumar A, Zhou Q, Wang Y, Hansen AL, Kutluay S, Roche J, Tolbert BS
R
g
Guinier
3.7
nm
D
max
14.0
nm
Volume
Porod
58
nm
3
SASDTE8
–
Heterogeneous
nuclear
ribonucleoprotein
A1
-A mutant (hnRNP
A1
-A(mut
)
)
at 0.1 MPa
Sample:
Isoform
A1
-A
of
Heterogeneous
nuclear
ribonucleoprotein
A1
(C43S/R75D/R88D/C175S
)
monomer, 34 kDa
Homo sapiens
protein
Buffer:
100 mM HEPES, 350 mM NaCl, 0.5 mM EDTA, pH: 7.5
Experiment:
SAXS data collected at G1, ...
)
on 2023 Mar 1
...
of
the tandem RRM domains
of
hnRNP
A1
underlie its pleiotropic RNA binding functions.
Sci Adv
10(28):eadk6580 (2024)
Levengood JD, Potoyan D, Penumutchu S, Kumar A, Zhou Q, Wang Y, Hansen AL, Kutluay S, Roche J, Tolbert BS
R
g
Guinier
3.6
nm
D
max
20.0
nm
Volume
Porod
98
nm
3
SASDTF8
–
Heterogeneous
nuclear
ribonucleoprotein
A1
-A mutant (hnRNP
A1
-A(mut
)
)
at 50 MPa
Sample:
Isoform
A1
-A
of
Heterogeneous
nuclear
ribonucleoprotein
A1
(C43S/R75D/R88D/C175S
)
monomer, 34 kDa
Homo sapiens
protein
Buffer:
100 mM HEPES, 350 mM NaCl, 0.5 mM EDTA, pH: 7.5
Experiment:
SAXS data collected at G1, ...
)
on 2023 Mar 1
...
of
the tandem RRM domains
of
hnRNP
A1
underlie its pleiotropic RNA binding functions.
Sci Adv
10(28):eadk6580 (2024)
Levengood JD, Potoyan D, Penumutchu S, Kumar A, Zhou Q, Wang Y, Hansen AL, Kutluay S, Roche J, Tolbert BS
R
g
Guinier
3.7
nm
D
max
23.0
nm
Volume
Porod
104
nm
3
SASDTG8
–
Heterogeneous
nuclear
ribonucleoprotein
A1
-A mutant (hnRNP
A1
-A(mut
)
)
at 100 MPa
Sample:
Isoform
A1
-A
of
Heterogeneous
nuclear
ribonucleoprotein
A1
(C43S/R75D/R88D/C175S
)
monomer, 34 kDa
Homo sapiens
protein
Buffer:
100 mM HEPES, 350 mM NaCl, 0.5 mM EDTA, pH: 7.5
Experiment:
SAXS data collected at G1, ...
)
on 2023 Mar 1
...
of
the tandem RRM domains
of
hnRNP
A1
underlie its pleiotropic RNA binding functions.
Sci Adv
10(28):eadk6580 (2024)
Levengood JD, Potoyan D, Penumutchu S, Kumar A, Zhou Q, Wang Y, Hansen AL, Kutluay S, Roche J, Tolbert BS
R
g
Guinier
3.6
nm
D
max
23.0
nm
Volume
Porod
94
nm
3
SASDTH8
–
Heterogeneous
nuclear
ribonucleoprotein
A1
-A mutant (hnRNP
A1
-A(mut
)
)
at 150 MPa
Sample:
Isoform
A1
-A
of
Heterogeneous
nuclear
ribonucleoprotein
A1
(C43S/R75D/R88D/C175S
)
monomer, 34 kDa
Homo sapiens
protein
Buffer:
100 mM HEPES, 350 mM NaCl, 0.5 mM EDTA, pH: 7.5
Experiment:
SAXS data collected at G1, ...
)
on 2023 Mar 1
...
of
the tandem RRM domains
of
hnRNP
A1
underlie its pleiotropic RNA binding functions.
Sci Adv
10(28):eadk6580 (2024)
Levengood JD, Potoyan D, Penumutchu S, Kumar A, Zhou Q, Wang Y, Hansen AL, Kutluay S, Roche J, Tolbert BS
R
g
Guinier
3.6
nm
D
max
23.0
nm
Volume
Porod
109
nm
3
SASDTJ8
–
Heterogeneous
nuclear
ribonucleoprotein
A1
-A mutant (hnRNP
A1
-A(mut
)
)
at 200 MPa
Sample:
Isoform
A1
-A
of
Heterogeneous
nuclear
ribonucleoprotein
A1
(C43S/R75D/R88D/C175S
)
monomer, 34 kDa
Homo sapiens
protein
Buffer:
100 mM HEPES, 350 mM NaCl, 0.5 mM EDTA, pH: 7.5
Experiment:
SAXS data collected at G1, ...
)
on 2023 Mar 1
...
of
the tandem RRM domains
of
hnRNP
A1
underlie its pleiotropic RNA binding functions.
Sci Adv
10(28):eadk6580 (2024)
Levengood JD, Potoyan D, Penumutchu S, Kumar A, Zhou Q, Wang Y, Hansen AL, Kutluay S, Roche J, Tolbert BS
R
g
Guinier
3.7
nm
SASDTK8
–
Heterogeneous
nuclear
ribonucleoprotein
A1
-A mutant (hnRNP
A1
-A(mut
)
)
at 250 MPa
Sample:
Isoform
A1
-A
of
Heterogeneous
nuclear
ribonucleoprotein
A1
(C43S/R75D/R88D/C175S
)
monomer, 34 kDa
Homo sapiens
protein
Buffer:
100 mM HEPES, 350 mM NaCl, 0.5 mM EDTA, pH: 7.5
Experiment:
SAXS data collected at G1, ...
)
on 2023 Mar 1
...
of
the tandem RRM domains
of
hnRNP
A1
underlie its pleiotropic RNA binding functions.
Sci Adv
10(28):eadk6580 (2024)
Levengood JD, Potoyan D, Penumutchu S, Kumar A, Zhou Q, Wang Y, Hansen AL, Kutluay S, Roche J, Tolbert BS
R
g
Guinier
3.6
nm
