|
|
|
Sample: |
humanized immunoglobulin G1 monoclonal antibody monomer, 148 kDa Mouse/human (chimera)
|
Buffer: |
100 mM glycine-HCl, 200 mM NaCl, pH: 2
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Experiment: |
SAXS
data collected at BL-10C, Photon Factory (PF), High Energy Accelerator Research Organization (KEK) on 2017 Mar 5
|
Getting Smaller by Denaturation: Acid-Induced Compaction of Antibodies
The Journal of Physical Chemistry Letters :3898-3906 (2023)
Imamura H, Ooishi A, Honda S
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RgGuinier |
4.1 |
nm |
Dmax |
14.2 |
nm |
VolumePorod |
240 |
nm3 |
|