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2 hits found for humanized immunoglobulin G1 monoclonal antibody

SASDQ99Immunoglobulin G1 (pH 2, 0 M NaCl), SEC-SAXS data

humanized immunoglobulin G1 monoclonal antibody experimental SAS data
humanized immunoglobulin G1 monoclonal antibody Kratky plot
Sample: humanized immunoglobulin G1 monoclonal antibody monomer, 148 kDa Mouse/human (chimera)
Buffer: 100 mM glycine-HCl, pH: 2
Experiment: SAXS data collected at BL-10C, Photon Factory (PF), High Energy Accelerator Research Organization (KEK) on 2016 Mar 2
Getting Smaller by Denaturation: Acid-Induced Compaction of Antibodies The Journal of Physical Chemistry Letters :3898-3906 (2023)
Imamura H, Ooishi A, Honda S
RgGuinier 5.1 nm
Dmax 17.6 nm
VolumePorod 260 nm3

SASDQA9Immunoglobulin G1 (pH 2, 0.2 M NaCl), SEC-SAXS data

humanized immunoglobulin G1 monoclonal antibody experimental SAS data
humanized immunoglobulin G1 monoclonal antibody Kratky plot
Sample: humanized immunoglobulin G1 monoclonal antibody monomer, 148 kDa Mouse/human (chimera)
Buffer: 100 mM glycine-HCl, 200 mM NaCl, pH: 2
Experiment: SAXS data collected at BL-10C, Photon Factory (PF), High Energy Accelerator Research Organization (KEK) on 2017 Mar 5
Getting Smaller by Denaturation: Acid-Induced Compaction of Antibodies The Journal of Physical Chemistry Letters :3898-3906 (2023)
Imamura H, Ooishi A, Honda S
RgGuinier 4.1 nm
Dmax 14.2 nm
VolumePorod 240 nm3