Small Angle Scattering Biological Data Bank SASBDB

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46 hits found for Chataigner

SASDL66 – High mannose neurofascin 155 immunoglobulin domains 1-6, 37.2 μM

Neurofascin experimental SAS data

Neurofascin Kratky plot

Sample:	Neurofascin dimer, 139 kDa Mus musculus protein
Buffer:	25 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment:	SAXS data collected at B21, Diamond Light Source on 2019 Dec 16

Structural insights into the contactin 1 – neurofascin 155 adhesion complex Nature Communications 13(1) (2022)
Chataigner L, Gogou C, den Boer M, Frias C, Thies-Weesie D, Granneman J, Heck A, Meijer D, Janssen B

R_g^Guinier	4.7	nm
D_max	18.0	nm
Volume^Porod	355	nm³

SASDL76 – High mannose neurofascin 155 immunoglobulin domains 1-6, 73.5 μM

Neurofascin experimental SAS data

Neurofascin Kratky plot

Sample:	Neurofascin dimer, 139 kDa Mus musculus protein
Buffer:	25 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment:	SAXS data collected at B21, Diamond Light Source on 2019 Dec 16

Structural insights into the contactin 1 – neurofascin 155 adhesion complex Nature Communications 13(1) (2022)
Chataigner L, Gogou C, den Boer M, Frias C, Thies-Weesie D, Granneman J, Heck A, Meijer D, Janssen B

R_g^Guinier	5.0	nm
D_max	21.0	nm
Volume^Porod	450	nm³

SASDL86 – High mannose neurofascin 155 immunoglobulin domains 1-6, 19.7 μM

Neurofascin experimental SAS data

Neurofascin Kratky plot

Sample:	Neurofascin dimer, 139 kDa Mus musculus protein
Buffer:	25 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment:	SAXS data collected at B21, Diamond Light Source on 2019 Dec 16

Structural insights into the contactin 1 – neurofascin 155 adhesion complex Nature Communications 13(1) (2022)
Chataigner L, Gogou C, den Boer M, Frias C, Thies-Weesie D, Granneman J, Heck A, Meijer D, Janssen B

R_g^Guinier	4.5	nm
D_max	17.0	nm
Volume^Porod	290	nm³

SASDL96 – High mannose neurofascin 155 immunoglobulin domains 1-6, 9.5 μM

Neurofascin experimental SAS data

Neurofascin Kratky plot

Sample:	Neurofascin dimer, 139 kDa Mus musculus protein
Buffer:	25 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment:	SAXS data collected at B21, Diamond Light Source on 2019 Dec 16

Structural insights into the contactin 1 – neurofascin 155 adhesion complex Nature Communications 13(1) (2022)
Chataigner L, Gogou C, den Boer M, Frias C, Thies-Weesie D, Granneman J, Heck A, Meijer D, Janssen B

R_g^Guinier	4.3	nm
D_max	17.0	nm
Volume^Porod	240	nm³

SASDLA6 – High mannose neurofascin 155 immunoglobulin domains 1-6, 5.1 μM

Neurofascin experimental SAS data

Neurofascin Kratky plot

Sample:	Neurofascin dimer, 139 kDa Mus musculus protein
Buffer:	25 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment:	SAXS data collected at B21, Diamond Light Source on 2019 Dec 16

Structural insights into the contactin 1 – neurofascin 155 adhesion complex Nature Communications 13(1) (2022)
Chataigner L, Gogou C, den Boer M, Frias C, Thies-Weesie D, Granneman J, Heck A, Meijer D, Janssen B

R_g^Guinier	4.2	nm
D_max	17.0	nm
Volume^Porod	207	nm³

SASDLB6 – High mannose neurofascin 155 immunoglobulin domains 1-6, 2.7 μM

Neurofascin experimental SAS data

Neurofascin Kratky plot

Sample:	Neurofascin dimer, 139 kDa Mus musculus protein
Buffer:	25 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment:	SAXS data collected at B21, Diamond Light Source on 2019 Dec 16

Structural insights into the contactin 1 – neurofascin 155 adhesion complex Nature Communications 13(1) (2022)
Chataigner L, Gogou C, den Boer M, Frias C, Thies-Weesie D, Granneman J, Heck A, Meijer D, Janssen B

R_g^Guinier	4.1	nm
D_max	17.0	nm
Volume^Porod	187	nm³

SASDLC6 – High mannose neurofascin 155 immunoglobulin domains 1-6, 1.3 μM

Neurofascin experimental SAS data

Neurofascin Kratky plot

Sample:	Neurofascin dimer, 139 kDa Mus musculus protein
Buffer:	25 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment:	SAXS data collected at B21, Diamond Light Source on 2019 Dec 16

Structural insights into the contactin 1 – neurofascin 155 adhesion complex Nature Communications 13(1) (2022)
Chataigner L, Gogou C, den Boer M, Frias C, Thies-Weesie D, Granneman J, Heck A, Meijer D, Janssen B

R_g^Guinier	3.9	nm
D_max	12.6	nm
Volume^Porod	172	nm³

SASDLD6 – High mannose neurofascin 155 immunoglobulin domains 1-6 Thr216Ala, 109.3 μM

Neurofascin T216A experimental SAS data

Neurofascin T216A Kratky plot

Sample:	Neurofascin T216A monomer, 70 kDa Mus musculus protein
Buffer:	25 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment:	SAXS data collected at B21, Diamond Light Source on 2020 Jun 25

Structural insights into the contactin 1 – neurofascin 155 adhesion complex Nature Communications 13(1) (2022)
Chataigner L, Gogou C, den Boer M, Frias C, Thies-Weesie D, Granneman J, Heck A, Meijer D, Janssen B

R_g^Guinier	4.3	nm
D_max	18.0	nm
Volume^Porod	212	nm³

SASDLE6 – High mannose neurofascin 155 immunoglobulin domains 1-6 Thr216Ala, 21.9 μM

Neurofascin T216A experimental SAS data

Neurofascin T216A Kratky plot

Sample:	Neurofascin T216A monomer, 70 kDa Mus musculus protein
Buffer:	25 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment:	SAXS data collected at B21, Diamond Light Source on 2020 Jun 25

Structural insights into the contactin 1 – neurofascin 155 adhesion complex Nature Communications 13(1) (2022)
Chataigner L, Gogou C, den Boer M, Frias C, Thies-Weesie D, Granneman J, Heck A, Meijer D, Janssen B

R_g^Guinier	3.9	nm
D_max	16.0	nm
Volume^Porod	158	nm³

SASDLF6 – High mannose neurofascin 155 immunoglobulin domains 1-6 Thr216Ala, 5.5 μM

Neurofascin T216A experimental SAS data

Neurofascin T216A Kratky plot

Sample:	Neurofascin T216A monomer, 70 kDa Mus musculus protein
Buffer:	25 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment:	SAXS data collected at B21, Diamond Light Source on 2020 Jun 25

Structural insights into the contactin 1 – neurofascin 155 adhesion complex Nature Communications 13(1) (2022)
Chataigner L, Gogou C, den Boer M, Frias C, Thies-Weesie D, Granneman J, Heck A, Meijer D, Janssen B

R_g^Guinier	3.8	nm
D_max	14.0	nm
Volume^Porod	150	nm³

SASDLG6 – High mannose neurofascin 155 immunoglobulin domains 1-6 Thr216Ala, 1.1 μM

Neurofascin T216A experimental SAS data

Neurofascin T216A Kratky plot

Sample:	Neurofascin T216A monomer, 70 kDa Mus musculus protein
Buffer:	25 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment:	SAXS data collected at B21, Diamond Light Source on 2020 Jun 25

Structural insights into the contactin 1 – neurofascin 155 adhesion complex Nature Communications 13(1) (2022)
Chataigner L, Gogou C, den Boer M, Frias C, Thies-Weesie D, Granneman J, Heck A, Meijer D, Janssen B

R_g^Guinier	3.6	nm
D_max	10.6	nm
Volume^Porod	139	nm³

SASDLH6 – Complex glycan contactin 1 immunoglobulin domains 1-6, 24.6 μM

Contactin-1 I433V experimental SAS data

Contactin-1 I433V Kratky plot

Sample:	Contactin-1 I433V dimer, 134 kDa Mus musculus protein
Buffer:	25 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment:	SAXS data collected at B21, Diamond Light Source on 2019 Dec 16

Structural insights into the contactin 1 – neurofascin 155 adhesion complex Nature Communications 13(1) (2022)
Chataigner L, Gogou C, den Boer M, Frias C, Thies-Weesie D, Granneman J, Heck A, Meijer D, Janssen B

R_g^Guinier	5.0	nm
D_max	23.0	nm
Volume^Porod	180	nm³

SASDLJ6 – Complex glycan contactin 1 immunoglobulin domains 1-6, 12.3 μM

Contactin-1 I433V experimental SAS data

Contactin-1 I433V Kratky plot

Sample:	Contactin-1 I433V dimer, 134 kDa Mus musculus protein
Buffer:	25 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment:	SAXS data collected at B21, Diamond Light Source on 2019 Dec 16

Structural insights into the contactin 1 – neurofascin 155 adhesion complex Nature Communications 13(1) (2022)
Chataigner L, Gogou C, den Boer M, Frias C, Thies-Weesie D, Granneman J, Heck A, Meijer D, Janssen B

R_g^Guinier	4.9	nm
D_max	23.0	nm
Volume^Porod	166	nm³

SASDLK6 – Complex glycan contactin 1 immunoglobulin domains 1-6, 6.2 μM

Contactin-1 I433V experimental SAS data

Contactin-1 I433V Kratky plot

Sample:	Contactin-1 I433V dimer, 134 kDa Mus musculus protein
Buffer:	25 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment:	SAXS data collected at B21, Diamond Light Source on 2019 Dec 16

Structural insights into the contactin 1 – neurofascin 155 adhesion complex Nature Communications 13(1) (2022)
Chataigner L, Gogou C, den Boer M, Frias C, Thies-Weesie D, Granneman J, Heck A, Meijer D, Janssen B

R_g^Guinier	4.9	nm
D_max	23.0	nm
Volume^Porod	155	nm³

SASDLL6 – Complex glycan contactin 1 immunoglobulin domains 1-6, 3.1 μM

Contactin-1 I433V experimental SAS data

Contactin-1 I433V Kratky plot

Sample:	Contactin-1 I433V dimer, 134 kDa Mus musculus protein
Buffer:	25 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment:	SAXS data collected at B21, Diamond Light Source on 2019 Dec 16

Structural insights into the contactin 1 – neurofascin 155 adhesion complex Nature Communications 13(1) (2022)
Chataigner L, Gogou C, den Boer M, Frias C, Thies-Weesie D, Granneman J, Heck A, Meijer D, Janssen B

R_g^Guinier	4.9	nm
D_max	15.8	nm
Volume^Porod	118	nm³

SASDLM6 – High mannose glycan contactin 1 immunoglobulin domains 1-6, 21.8 μM

Contactin-1 I433V experimental SAS data

Contactin-1 I433V Kratky plot

Sample:	Contactin-1 I433V dimer, 134 kDa Mus musculus protein
Buffer:	25 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment:	SAXS data collected at B21, Diamond Light Source on 2019 Dec 16

Structural insights into the contactin 1 – neurofascin 155 adhesion complex Nature Communications 13(1) (2022)
Chataigner L, Gogou C, den Boer M, Frias C, Thies-Weesie D, Granneman J, Heck A, Meijer D, Janssen B

R_g^Guinier	5.2	nm
D_max	23.0	nm
Volume^Porod	154	nm³

SASDLN6 – High mannose glycan contactin 1 immunoglobulin domains 1-6, 10.9 μM

Contactin-1 I433V experimental SAS data

Contactin-1 I433V Kratky plot

Sample:	Contactin-1 I433V dimer, 134 kDa Mus musculus protein
Buffer:	25 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment:	SAXS data collected at B21, Diamond Light Source on 2019 Dec 16

Structural insights into the contactin 1 – neurofascin 155 adhesion complex Nature Communications 13(1) (2022)
Chataigner L, Gogou C, den Boer M, Frias C, Thies-Weesie D, Granneman J, Heck A, Meijer D, Janssen B

R_g^Guinier	5.0	nm
D_max	23.0	nm
Volume^Porod	150	nm³

SASDLP6 – High mannose glycan contactin 1 immunoglobulin domains 1-6, 5.5 μM

Contactin-1 I433V experimental SAS data

Contactin-1 I433V Kratky plot

Sample:	Contactin-1 I433V dimer, 134 kDa Mus musculus protein
Buffer:	25 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment:	SAXS data collected at B21, Diamond Light Source on 2019 Dec 16

Structural insights into the contactin 1 – neurofascin 155 adhesion complex Nature Communications 13(1) (2022)
Chataigner L, Gogou C, den Boer M, Frias C, Thies-Weesie D, Granneman J, Heck A, Meijer D, Janssen B

R_g^Guinier	5.0	nm
D_max	23.0	nm
Volume^Porod	146	nm³

SASDLQ6 – High mannose glycan contactin 1 immunoglobulin domains 1-6, 2.7 μM

Contactin-1 I433V experimental SAS data

CUSTOM IN-HOUSE model

Sample:	Contactin-1 I433V dimer, 134 kDa Mus musculus protein
Buffer:	25 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment:	SAXS data collected at B21, Diamond Light Source on 2019 Dec 16

Structural insights into the contactin 1 – neurofascin 155 adhesion complex Nature Communications 13(1) (2022)
Chataigner L, Gogou C, den Boer M, Frias C, Thies-Weesie D, Granneman J, Heck A, Meijer D, Janssen B

R_g^Guinier	4.9	nm
D_max	14.5	nm
Volume^Porod	100	nm³

SASDLR6 – Complex glycan contactin 1 ectodomain, 20 μM

Contactin-1 I433V experimental SAS data

Contactin-1 I433V Kratky plot

Sample:	Contactin-1 I433V dimer, 220 kDa Mus musculus protein
Buffer:	25 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment:	SAXS data collected at B21, Diamond Light Source on 2019 Dec 16

Structural insights into the contactin 1 – neurofascin 155 adhesion complex Nature Communications 13(1) (2022)
Chataigner L, Gogou C, den Boer M, Frias C, Thies-Weesie D, Granneman J, Heck A, Meijer D, Janssen B

R_g^Guinier	8.1	nm
D_max	42.0	nm
Volume^Porod	520	nm³

SASDLS6 – Complex glycan contactin 1 ectodomain, 10 μM

Contactin-1 I433V experimental SAS data

Contactin-1 I433V Kratky plot

Sample:	Contactin-1 I433V dimer, 220 kDa Mus musculus protein
Buffer:	25 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment:	SAXS data collected at B21, Diamond Light Source on 2019 Dec 16

Structural insights into the contactin 1 – neurofascin 155 adhesion complex Nature Communications 13(1) (2022)
Chataigner L, Gogou C, den Boer M, Frias C, Thies-Weesie D, Granneman J, Heck A, Meijer D, Janssen B

R_g^Guinier	8.0	nm
D_max	43.0	nm
Volume^Porod	530	nm³

SASDLT6 – Complex glycan contactin 1 ectodomain, 5 μM

Contactin-1 I433V experimental SAS data

Contactin-1 I433V Kratky plot

Sample:	Contactin-1 I433V dimer, 220 kDa Mus musculus protein
Buffer:	25 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment:	SAXS data collected at B21, Diamond Light Source on 2019 Dec 16

Structural insights into the contactin 1 – neurofascin 155 adhesion complex Nature Communications 13(1) (2022)
Chataigner L, Gogou C, den Boer M, Frias C, Thies-Weesie D, Granneman J, Heck A, Meijer D, Janssen B

R_g^Guinier	8.0	nm
D_max	43.0	nm
Volume^Porod	530	nm³

SASDLU6 – Complex glycan contactin 1 ectodomain, 2.5 μM

Contactin-1 I433V experimental SAS data

Contactin-1 I433V Kratky plot

Sample:	Contactin-1 I433V dimer, 220 kDa Mus musculus protein
Buffer:	25 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment:	SAXS data collected at B21, Diamond Light Source on 2019 Dec 16

Structural insights into the contactin 1 – neurofascin 155 adhesion complex Nature Communications 13(1) (2022)
Chataigner L, Gogou C, den Boer M, Frias C, Thies-Weesie D, Granneman J, Heck A, Meijer D, Janssen B

R_g^Guinier	8.0	nm
D_max	25.7	nm
Volume^Porod	350	nm³

SASDLV6 – High mannose glycan contactin 1 ectodomain, 20.5 μM

Contactin-1 I433V experimental SAS data

Contactin-1 I433V Kratky plot

Sample:	Contactin-1 I433V dimer, 220 kDa Mus musculus protein
Buffer:	25 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment:	SAXS data collected at B21, Diamond Light Source on 2019 Dec 16

Structural insights into the contactin 1 – neurofascin 155 adhesion complex Nature Communications 13(1) (2022)
Chataigner L, Gogou C, den Boer M, Frias C, Thies-Weesie D, Granneman J, Heck A, Meijer D, Janssen B

R_g^Guinier	7.0	nm
D_max	34.0	nm
Volume^Porod	285	nm³

SASDLW6 – High mannose glycan contactin 1 ectodomain, 11.1 μM

Contactin-1 I433V experimental SAS data

Contactin-1 I433V Kratky plot

Sample:	Contactin-1 I433V dimer, 220 kDa Mus musculus protein
Buffer:	25 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment:	SAXS data collected at B21, Diamond Light Source on 2019 Dec 16

Structural insights into the contactin 1 – neurofascin 155 adhesion complex Nature Communications 13(1) (2022)
Chataigner L, Gogou C, den Boer M, Frias C, Thies-Weesie D, Granneman J, Heck A, Meijer D, Janssen B

R_g^Guinier	6.8	nm
D_max	27.0	nm
Volume^Porod	275	nm³

SASDLX6 – High mannose glycan contactin 1 ectodomain, 5.5 μM

Contactin-1 I433V experimental SAS data

Contactin-1 I433V Kratky plot

Sample:	Contactin-1 I433V dimer, 220 kDa Mus musculus protein
Buffer:	25 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment:	SAXS data collected at B21, Diamond Light Source on 2019 Dec 16

Structural insights into the contactin 1 – neurofascin 155 adhesion complex Nature Communications 13(1) (2022)
Chataigner L, Gogou C, den Boer M, Frias C, Thies-Weesie D, Granneman J, Heck A, Meijer D, Janssen B

R_g^Guinier	6.8	nm
D_max	27.0	nm
Volume^Porod	270	nm³

SASDLY6 – High mannose glycan contactin 1 ectodomain, 2.4 μM

Contactin-1 I433V experimental SAS data

CUSTOM IN-HOUSE model

Sample:	Contactin-1 I433V dimer, 220 kDa Mus musculus protein
Buffer:	25 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment:	SAXS data collected at B21, Diamond Light Source on 2019 Dec 16

Structural insights into the contactin 1 – neurofascin 155 adhesion complex Nature Communications 13(1) (2022)
Chataigner L, Gogou C, den Boer M, Frias C, Thies-Weesie D, Granneman J, Heck A, Meijer D, Janssen B

R_g^Guinier	6.8	nm
D_max	19.5	nm
Volume^Porod	254	nm³

SASDNP8 – High mannose contactin-2 immunoglobulin domains1-6, 1μM

Contactin-2 experimental SAS data

Contactin-2 Kratky plot

Sample:	Contactin-2 dimer, 150 kDa Mus musculus protein
Buffer:	25 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment:	SAXS data collected at B21, Diamond Light Source on 2019 Dec 17

Contactin 2 homophilic adhesion structure and conformational plasticity Structure (2023)
Chataigner L, Thärichen L, Beugelink J, Granneman J, Mokiem N, Snijder J, Förster F, Janssen B

R_g^Guinier	5.1	nm
D_max	20.0	nm
Volume^Porod	140	nm³

SASDNQ8 – High mannose contactin 2 immunoglobulin domains1-6, 3μM

Contactin-2 experimental SAS data

Contactin-2 Kratky plot

Sample:	Contactin-2 dimer, 150 kDa Mus musculus protein
Buffer:	25 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment:	SAXS data collected at B21, Diamond Light Source on 2019 Dec 17

Contactin 2 homophilic adhesion structure and conformational plasticity Structure (2023)
Chataigner L, Thärichen L, Beugelink J, Granneman J, Mokiem N, Snijder J, Förster F, Janssen B

R_g^Guinier	5.3	nm
D_max	20.0	nm
Volume^Porod	300	nm³

SASDNR8 – High mannose contactin-2 immunoglobulin domains1-6, 6μM

Contactin-2 experimental SAS data

Contactin-2 Kratky plot

Sample:	Contactin-2 dimer, 150 kDa Mus musculus protein
Buffer:	25 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment:	SAXS data collected at B21, Diamond Light Source on 2019 Dec 17

Contactin 2 homophilic adhesion structure and conformational plasticity Structure (2023)
Chataigner L, Thärichen L, Beugelink J, Granneman J, Mokiem N, Snijder J, Förster F, Janssen B

R_g^Guinier	5.4	nm
D_max	21.0	nm
Volume^Porod	325	nm³

SASDNS8 – High mannose contactin-2 immunoglobulin domains1-6, 13μM

Contactin-2 experimental SAS data

Contactin-2 Kratky plot

Sample:	Contactin-2 dimer, 150 kDa Mus musculus protein
Buffer:	25 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment:	SAXS data collected at B21, Diamond Light Source on 2019 Dec 17

Contactin 2 homophilic adhesion structure and conformational plasticity Structure (2023)
Chataigner L, Thärichen L, Beugelink J, Granneman J, Mokiem N, Snijder J, Förster F, Janssen B

R_g^Guinier	5.5	nm
D_max	21.4	nm
Volume^Porod	350	nm³

SASDNT8 – High mannose contactin-2 immunoglobulin domains1-6, 26μM

Contactin-2 experimental SAS data

Contactin-2 Kratky plot

Sample:	Contactin-2 dimer, 150 kDa Mus musculus protein
Buffer:	25 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment:	SAXS data collected at B21, Diamond Light Source on 2019 Dec 17

Contactin 2 homophilic adhesion structure and conformational plasticity Structure (2023)
Chataigner L, Thärichen L, Beugelink J, Granneman J, Mokiem N, Snijder J, Förster F, Janssen B

R_g^Guinier	6.0	nm
D_max	30.0	nm
Volume^Porod	380	nm³

SASDNU8 – High mannose contactin-2 immunoglobulin domains1-6, 52μM

Contactin-2 experimental SAS data

Contactin-2 Kratky plot

Sample:	Contactin-2 dimer, 150 kDa Mus musculus protein
Buffer:	25 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment:	SAXS data collected at B21, Diamond Light Source on 2019 Dec 17

Contactin 2 homophilic adhesion structure and conformational plasticity Structure (2023)
Chataigner L, Thärichen L, Beugelink J, Granneman J, Mokiem N, Snijder J, Förster F, Janssen B

R_g^Guinier	6.1	nm
D_max	32.0	nm
Volume^Porod	408	nm³

SASDNV8 – Complex glycan contactin-2 immunoglobulin domains1-6, 1μM

Contactin-2 experimental SAS data

Contactin-2 Kratky plot

Sample:	Contactin-2 dimer, 157 kDa Mus musculus protein
Buffer:	25 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment:	SAXS data collected at B21, Diamond Light Source on 2019 Dec 17

Contactin 2 homophilic adhesion structure and conformational plasticity Structure (2023)
Chataigner L, Thärichen L, Beugelink J, Granneman J, Mokiem N, Snijder J, Förster F, Janssen B

R_g^Guinier	5.6	nm
D_max	25.0	nm
Volume^Porod	230	nm³

SASDNW8 – Complex glycan contactin-2 immunoglobulin domains1-6, 3μM

Contactin-2 experimental SAS data

Contactin-2 Kratky plot

Sample:	Contactin-2 dimer, 157 kDa Mus musculus protein
Buffer:	25 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment:	SAXS data collected at B21, Diamond Light Source on 2019 Dec 17

Contactin 2 homophilic adhesion structure and conformational plasticity Structure (2023)
Chataigner L, Thärichen L, Beugelink J, Granneman J, Mokiem N, Snijder J, Förster F, Janssen B

R_g^Guinier	5.4	nm
D_max	25.0	nm
Volume^Porod	185	nm³

SASDNX8 – Complex glycan contactin-2 immunoglobulin domains1-6, 5μM

Contactin-2 experimental SAS data

Contactin-2 Kratky plot

Sample:	Contactin-2 dimer, 157 kDa Mus musculus protein
Buffer:	25 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment:	SAXS data collected at B21, Diamond Light Source on 2019 Dec 17

Contactin 2 homophilic adhesion structure and conformational plasticity Structure (2023)
Chataigner L, Thärichen L, Beugelink J, Granneman J, Mokiem N, Snijder J, Förster F, Janssen B

R_g^Guinier	5.5	nm
D_max	22.0	nm
Volume^Porod	353	nm³

SASDNY8 – Complex glycan contactin-2 immunoglobulin domains1-6, 11μM

Contactin-2 experimental SAS data

Contactin-2 Kratky plot

Sample:	Contactin-2 dimer, 157 kDa Mus musculus protein
Buffer:	25 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment:	SAXS data collected at B21, Diamond Light Source on 2019 Dec 17

Contactin 2 homophilic adhesion structure and conformational plasticity Structure (2023)
Chataigner L, Thärichen L, Beugelink J, Granneman J, Mokiem N, Snijder J, Förster F, Janssen B

R_g^Guinier	5.5	nm
D_max	22.0	nm
Volume^Porod	365	nm³

SASDNZ8 – Complex glycan contactin-2 immunoglobulin domains1-6, 24μM

Contactin-2 experimental SAS data

Contactin-2 Kratky plot

Sample:	Contactin-2 dimer, 157 kDa Mus musculus protein
Buffer:	25 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment:	SAXS data collected at B21, Diamond Light Source on 2019 Dec 17

Contactin 2 homophilic adhesion structure and conformational plasticity Structure (2023)
Chataigner L, Thärichen L, Beugelink J, Granneman J, Mokiem N, Snijder J, Förster F, Janssen B

R_g^Guinier	5.6	nm
D_max	22.0	nm
Volume^Porod	390	nm³

SASDN29 – Complex glycan contactin-2 immunoglobulin domains1-6, 51μM

Contactin-2 experimental SAS data

Contactin-2 Kratky plot

Sample:	Contactin-2 dimer, 157 kDa Mus musculus protein
Buffer:	25 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment:	SAXS data collected at B21, Diamond Light Source on 2019 Dec 7

Contactin 2 homophilic adhesion structure and conformational plasticity Structure (2023)
Chataigner L, Thärichen L, Beugelink J, Granneman J, Mokiem N, Snijder J, Förster F, Janssen B

R_g^Guinier	5.8	nm
D_max	32.0	nm
Volume^Porod	412	nm³

SASDN39 – Complex glycan contactin-2 ectodomain, 1 μM

Contactin-2 experimental SAS data

Contactin-2 Kratky plot

Sample:	Contactin-2 trimer, 389 kDa Mus musculus protein
Buffer:	25 mM HEPES, 500 mM NaCl, 500 mM imidazole, pH: 7.5
Experiment:	SAXS data collected at B21, Diamond Light Source on 2019 Dec 17

Contactin 2 homophilic adhesion structure and conformational plasticity Structure (2023)
Chataigner L, Thärichen L, Beugelink J, Granneman J, Mokiem N, Snijder J, Förster F, Janssen B

R_g^Guinier	9.3	nm
D_max	45.0	nm
Volume^Porod	780	nm³

SASDN49 – Complex glycan contactin-2 ectodomain, 2 μM

Contactin-2 experimental SAS data

Contactin-2 Kratky plot

Sample:	Contactin-2 trimer, 389 kDa Mus musculus protein
Buffer:	25 mM HEPES, 500 mM NaCl, 500 mM imidazole, pH: 7.5
Experiment:	SAXS data collected at B21, Diamond Light Source on 2019 Dec 17

Contactin 2 homophilic adhesion structure and conformational plasticity Structure (2023)
Chataigner L, Thärichen L, Beugelink J, Granneman J, Mokiem N, Snijder J, Förster F, Janssen B

R_g^Guinier	10.3	nm
D_max	60.0	nm
Volume^Porod	1290	nm³

SASDN59 – Complex glycan contactin-2 ectodomain, 3 μM

Contactin-2 experimental SAS data

Contactin-2 Kratky plot

Sample:	Contactin-2 trimer, 389 kDa Mus musculus protein
Buffer:	25 mM HEPES, 500 mM NaCl, 500 mM imidazole, pH: 7.5
Experiment:	SAXS data collected at B21, Diamond Light Source on 2019 Dec 17

Contactin 2 homophilic adhesion structure and conformational plasticity Structure (2023)
Chataigner L, Thärichen L, Beugelink J, Granneman J, Mokiem N, Snijder J, Förster F, Janssen B

R_g^Guinier	11.2	nm
D_max	60.0	nm
Volume^Porod	1540	nm³

SASDN69 – Complex glycan contactin-2 ectodomain, 6 μM

Contactin-2 experimental SAS data

Contactin-2 Kratky plot

Sample:	Contactin-2 trimer, 389 kDa Mus musculus protein
Buffer:	25 mM HEPES, 500 mM NaCl, 500 mM imidazole, pH: 7.5
Experiment:	SAXS data collected at B21, Diamond Light Source on 2019 Dec 17

Contactin 2 homophilic adhesion structure and conformational plasticity Structure (2023)
Chataigner L, Thärichen L, Beugelink J, Granneman J, Mokiem N, Snijder J, Förster F, Janssen B

R_g^Guinier	11.0	nm
D_max	70.0	nm
Volume^Porod	1900	nm³

SASDN79 – Complex glycan contactin-2 ectodomain, 12 μM

Contactin-2 experimental SAS data

Contactin-2 Kratky plot

Sample:	Contactin-2 trimer, 389 kDa Mus musculus protein
Buffer:	25 mM HEPES, 500 mM NaCl, 500 mM imidazole, pH: 7.5
Experiment:	SAXS data collected at B21, Diamond Light Source on 2019 Dec 17

Contactin 2 homophilic adhesion structure and conformational plasticity Structure (2023)
Chataigner L, Thärichen L, Beugelink J, Granneman J, Mokiem N, Snijder J, Förster F, Janssen B

R_g^Guinier	11.3	nm
D_max	66.0	nm
Volume^Porod	1820	nm³

SASDN89 – Complex glycan contactin-2 ectodomain, 23 μM

Contactin-2 experimental SAS data

Contactin-2 Kratky plot

Sample:	Contactin-2 trimer, 389 kDa Mus musculus protein
Buffer:	25 mM HEPES, 500 mM NaCl, 500 mM imidazole, pH: 7.5
Experiment:	SAXS data collected at B21, Diamond Light Source on 2019 Dec 17

Contactin 2 homophilic adhesion structure and conformational plasticity Structure (2023)
Chataigner L, Thärichen L, Beugelink J, Granneman J, Mokiem N, Snijder J, Förster F, Janssen B

R_g^Guinier	12.5	nm
D_max	65.0	nm
Volume^Porod	2044	nm³

SASDN99 – Complex glycan contactin-2 ectodomain, 50 μM

Contactin-2 experimental SAS data

Contactin-2 Kratky plot

Sample:	Contactin-2 trimer, 389 kDa Mus musculus protein
Buffer:	25 mM HEPES, 500 mM NaCl, 500 mM imidazole, pH: 7.5
Experiment:	SAXS data collected at B21, Diamond Light Source on 2019 Dec 17

Contactin 2 homophilic adhesion structure and conformational plasticity Structure (2023)
Chataigner L, Thärichen L, Beugelink J, Granneman J, Mokiem N, Snijder J, Förster F, Janssen B

R_g^Guinier	14.2	nm
D_max	65.0	nm
Volume^Porod	2190	nm³