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5 hits found for Moryachkov

SASDK36 – LC-18t - ssDNA aptamer specific to lung adenocarcinoma cancer cells

Lung adenocarcinoma aptamer, truncated version experimental SAS data
GROMACS model
Sample: Lung adenocarcinoma aptamer, truncated version monomer, 11 kDa Artificially synthesized DNA
Buffer: Phosphate-buffered saline, pH: 7.4
Experiment: SAXS data collected at EMBL P12, PETRA III on 2018 Oct 28
The Role of Small-Angle X-Ray Scattering and Molecular Simulations in 3D Structure Elucidation of a DNA Aptamer Against Lung Cancer Molecular Therapy - Nucleic Acids (2021)
...Moryachkov R, Shchugoreva I, Artyushenko P, Zamay G, Kolovskaya O, Zamay T, Krat A, Molodenskiy D, Zabluda V, Veprintsev D, Sokolov A, Zukov R, Berezovski M, Tomilin F, Fedorov D, Alexeev Y, Kichkailo...
RgGuinier 2.1 nm
Dmax 6.7 nm
VolumePorod 16 nm3

SASDMU7 – Apt31 - ssDNA aptamer specific to the receptor-binding domain of SARS-CoV-2

ssDNA aptamer Apt31 specific to the receptor-binding domain of SARS-CoV-2 experimental SAS data
GROMACS model
Sample: ssDNA aptamer Apt31 specific to the receptor-binding domain of SARS-CoV-2 monomer, 10 kDa Artificially synthesized DNA
Buffer: Tris-HCl, pH: 7.4
Experiment: SAXS data collected at 13A, Taiwan Photon Source, NSRRC on 2020 Dec 18
Structure and Interaction Based Design of Anti‐SARS‐CoV‐2 Aptamers Chemistry – A European Journal (2022)
...Moryachkov R, Kolovskaya O, Lukyanenko K, Song Y, Merkuleva I, Zabluda V, Peters G, Koroleva L, Veprintsev D, Glazyrin Y, Volosnikova E, Belenkaya S, Esina T, Isaeva A, Nesmeyanova V, Shanshin D, Berl...
RgGuinier 1.9 nm
Dmax 6.5 nm
VolumePorod 12 nm3

SASDPZ8 – Gli-233 - ssDNA aptamer specific to glioma brain tumor cells

Gli-233 - ssDNA aptamer to glioma brain tumor cells experimental SAS data
GROMACS model
Sample: Gli-233 - ssDNA aptamer to glioma brain tumor cells monomer, 10 kDa Artificially synthesized DNA
Buffer: Dulbecco phosphate-buffered saline (DPBS, with Ca and Mg), pH: 7.4
Experiment: SAXS data collected at BM29, ESRF on 2018 Jun 17
Development of DNA Aptamers for Visualization of Glial Brain Tumors and Detection of Circulating Tumor Cells Molecular Therapy - Nucleic Acids (2023)
...Moryachkov R, Zabluda V, Shchugoreva I, Artyushenko P, Mironov V, Morozov D, Khorzhevskii V, Gorbushin A, Koshmanova A, Nikolaeva E, Grinev I, Voronkovskii I, Grek D, Belugin K, Volzhentsev A, Badmaev...
RgGuinier 1.9 nm
Dmax 6.8 nm
VolumePorod 13 nm3

SASDRY7 – Gli-55 - ssDNA aptamer to glioma brain tumor cells

Gli-55 - ssDNA aptamer to glioma brain tumor cells experimental SAS data
DAMMIF model
Sample: Gli-55 - ssDNA aptamer to glioma brain tumor cells monomer, 19 kDa synthetic construct DNA
Buffer: Dulbecco phosphate-buffered saline (DPBS), pH: 7.4
Experiment: SAXS data collected at EMBL P12, PETRA III on 2018 Oct 30
Development of DNA Aptamers for Visualization of Glial Brain Tumors and Detection of Circulating Tumor Cells Molecular Therapy - Nucleic Acids (2023)
...Moryachkov R, Zabluda V, Shchugoreva I, Artyushenko P, Mironov V, Morozov D, Khorzhevskii V, Gorbushin A, Koshmanova A, Nikolaeva E, Grinev I, Voronkovskii I, Grek D, Belugin K, Volzhentsev A, Badmaev...
RgGuinier 2.8 nm
Dmax 11.5 nm
VolumePorod 35 nm3

SASDP29 – Gli-55 - ssDNA aptamer specific to glioma brain tumor cells

Gli-55 - ssDNA aptamer specific to glioma brain tumor cells experimental SAS data
DAMMIN model
Sample: Gli-55 - ssDNA aptamer specific to glioma brain tumor cells monomer, 19 kDa Artificially synthesized DNA
Buffer: Dulbecco phosphate-buffered saline (DPBS), pH: 7.4
Experiment: SAXS data collected at EMBL P12, PETRA III on 2018 Oct 30
Development of DNA Aptamers for Visualization of Glial Brain Tumors and Detection of Circulating Tumor Cells Molecular Therapy - Nucleic Acids (2023)
...Moryachkov R, Zabluda V, Shchugoreva I, Artyushenko P, Mironov V, Morozov D, Khorzhevskii V, Gorbushin A, Koshmanova A, Nikolaeva E, Grinev I, Voronkovskii I, Grek D, Belugin K, Volzhentsev A, Badmaev...
RgGuinier 2.8 nm
Dmax 11.5 nm
VolumePorod 34 nm3