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2 hits found for ISG75

SASDTP5 – Invariant surface glycoprotein 75 (N134A) amino acids 29-468

Invariant surface glycoprotein (N134A) experimental SAS data
CORAL model
Sample: Invariant surface glycoprotein (N134A) monomer, 49 kDa Trypanosoma brucei protein
Buffer: 20 mM Tris-HCl, 75 mM KCl, pH: 7.6
Experiment: SAXS data collected at EMBL P12, PETRA III on 2015 Aug 18
Trypanosoma brucei Invariant Surface Glycoprotein 75 Is an Immunoglobulin Fc Receptor Inhibiting Complement Activation and Antibody-Mediated Cellular Phagocytosis. J Immunol (2024)
Mikkelsen JH, Stødkilde K, Jensen MP, Hansen AG, Wu Q, Lorentzen J, Graversen JH, Andersen GR, Fenton RA, Etzerodt A, Thiel S, Andersen CBF
RgGuinier 3.6 nm
Dmax 15.0 nm
VolumePorod 127 nm3

SASDT95 – ...ISG75)

ISG75 experimental SAS data
BILBOMD model
Sample: ISG75 monomer, 50 kDa Trypanosoma brucei gambiense protein
Buffer: 20 mM HEPES, 150 mM NaCl, 3% glycerol, pH: 7.5
Experiment: SAXS data collected at BM29, ESRF on 2020 Nov 25
Beyond the VSG Layer: Exploring the Role of Intrinsic Disorder in the Invariant Surface Glycoproteins of African Trypanosomes. PLoS Pathog 20(4):e1012186 (2024)
Sülzen H, Volkov AN, Geens R, Zahedifard F, Stijlemans B, Zoltner M, Magez S, Sterckx YG, Zoll S
RgGuinier 3.2 nm
Dmax 11.1 nm
VolumePorod 85 nm3