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35 hits found for Zhu

SASDR32 – Human derived autoantibody mAb2G7 at pH 8.0

Human derived autoantibody mAb2G7 heavy chain, mAb2G7 VHHuman derived autoantibody mAb2G7 light chain, mAb2G7 VL experimental SAS data
Human derived autoantibody mAb2G7 heavy chain, mAb2G7 VH Human derived autoantibody mAb2G7 light chain, mAb2G7 VL Kratky plot
Sample: Human derived autoantibody mAb2G7 heavy chain, mAb2G7 VH dimer, 103 kDa protein
Human derived autoantibody mAb2G7 light chain, mAb2G7 VL dimer, 51 kDa protein
Buffer: phosphate buffered saline, pH: 8
Experiment: SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2022 Dec 8
Structural basis for antibody-mediated NMDA receptor clustering and endocytosis in autoimmune encephalitis. Nat Struct Mol Biol (2024)
...Zhu S
RgGuinier 5.0 nm
Dmax 16.0 nm
VolumePorod 260 nm3

SASDR42 – Human derived autoantibody mAb5F6 at pH 8.0

Human derived autoantibody mAb2G7 heavy chain, mAb2G7 VHHuman derived autoantibody mAb2G7 light chain, mAb2G7 VL experimental SAS data
Human derived autoantibody mAb2G7 heavy chain, mAb2G7 VH Human derived autoantibody mAb2G7 light chain, mAb2G7 VL Kratky plot
Sample: Human derived autoantibody mAb2G7 heavy chain, mAb2G7 VH dimer, 103 kDa protein
Human derived autoantibody mAb2G7 light chain, mAb2G7 VL dimer, 51 kDa protein
Buffer: phosphate buffered saline, pH: 8
Experiment: SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2022 Dec 8
Structural basis for antibody-mediated NMDA receptor clustering and endocytosis in autoimmune encephalitis. Nat Struct Mol Biol (2024)
...Zhu S
RgGuinier 5.0 nm
Dmax 15.8 nm
VolumePorod 252 nm3

SASDR52 – Human GluN1-GluN2A NMDA receptor at pH 8.0

Glutamate receptor ionotropic, NMDA 1Glutamate receptor ionotropic, NMDA 2A experimental SAS data
Glutamate receptor ionotropic, NMDA 1 Glutamate receptor ionotropic, NMDA 2A Kratky plot
Sample: Glutamate receptor ionotropic, NMDA 1 dimer, 193 kDa Homo sapiens protein
Glutamate receptor ionotropic, NMDA 2A dimer, 191 kDa Homo sapiens protein
Buffer: 150 mM NaCl, 0.1% digitonin, 5 µM Cholesteryl Hemisuccinate TRIS Salt, 0.1 mM CHAPSO, 50 µM EDTA,1 mM Gly/Glu, 20 mM HEPES, pH: 8
Experiment: SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2022 Dec 8
Structural basis for antibody-mediated NMDA receptor clustering and endocytosis in autoimmune encephalitis. Nat Struct Mol Biol (2024)
...Zhu S
RgGuinier 6.6 nm
Dmax 20.4 nm
VolumePorod 1180 nm3

SASDR62 – Human GluN1-GluN2A NMDA receptor in complex with human derived autoantibody mAb2G7 at pH 8.0

Glutamate receptor ionotropic, NMDA 1Glutamate receptor ionotropic, NMDA 2AHuman derived autoantibody mAb2G7 heavy chain, mAb2G7 VHHuman derived autoantibody mAb2G7 light chain, mAb2G7 VL experimental SAS data
Glutamate receptor ionotropic, NMDA 1 Glutamate receptor ionotropic, NMDA 2A Human derived autoantibody mAb2G7 heavy chain, mAb2G7 VH Human derived autoantibody mAb2G7 light chain, mAb2G7 VL Kratky plot
Sample: Glutamate receptor ionotropic, NMDA 1 dimer, 193 kDa Homo sapiens protein
Glutamate receptor ionotropic, NMDA 2A dimer, 191 kDa Homo sapiens protein
Human derived autoantibody mAb2G7 heavy chain, mAb2G7 VH dimer, 103 kDa protein
Human derived autoantibody mAb2G7 light chain, mAb2G7 VL dimer, 51 kDa protein
Buffer: 150 mM NaCl, 0.1% digitonin, 5 µM Cholesteryl Hemisuccinate TRIS Salt, 0.1 mM CHAPSO, 50 µM EDTA,1 mM Gly/Glu, 20 mM HEPES, pH: 8
Experiment: SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2022 Dec 8
Structural basis for antibody-mediated NMDA receptor clustering and endocytosis in autoimmune encephalitis. Nat Struct Mol Biol (2024)
...Zhu S
RgGuinier 7.7 nm
Dmax 25.4 nm
VolumePorod 1260 nm3

SASDR72 – Human GluN1-GluN2A NMDA receptor in complex with human derived autoantibody mAb5F6 at pH 8.0

Glutamate receptor ionotropic, NMDA 1Glutamate receptor ionotropic, NMDA 2AHuman derived autoantibody mAb5F6 heavy chain, mAb5F6 VHHuman derived autoantibody mAb5F6 light chain, mAb5F6 VL experimental SAS data
Glutamate receptor ionotropic, NMDA 1 Glutamate receptor ionotropic, NMDA 2A Human derived autoantibody mAb5F6 heavy chain, mAb5F6 VH Human derived autoantibody mAb5F6 light chain, mAb5F6 VL Kratky plot
Sample: Glutamate receptor ionotropic, NMDA 1 dimer, 193 kDa Homo sapiens protein
Glutamate receptor ionotropic, NMDA 2A dimer, 191 kDa Homo sapiens protein
Human derived autoantibody mAb5F6 heavy chain, mAb5F6 VH dimer, 104 kDa Homo sapiens protein
Human derived autoantibody mAb5F6 light chain, mAb5F6 VL dimer, 52 kDa protein
Buffer: 150 mM NaCl, 0.1% digitonin, 5 µM Cholesteryl Hemisuccinate TRIS Salt, 0.1 mM CHAPSO, 50 µM EDTA,1 mM Gly/Glu, 20 mM HEPES, pH: 8
Experiment: SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2022 Dec 8
Structural basis for antibody-mediated NMDA receptor clustering and endocytosis in autoimmune encephalitis. Nat Struct Mol Biol (2024)
...Zhu S
RgGuinier 9.9 nm
Dmax 31.7 nm
VolumePorod 2500 nm3

SASDHC2 – PieE-FAD: 2,4-dichlorophenol 6-monooxygenase bound to flavin adenine dinucleotide

2,4-dichlorophenol 6-monooxygenaseFlavin adenine dinucleotide experimental SAS data
DAMMIN model
Sample: 2,4-dichlorophenol 6-monooxygenase hexamer, 399 kDa Streptomyces sp. SCSIO … protein
Flavin adenine dinucleotide hexamer, 5 kDa
Buffer: 20 mM Tris, 150 mM NaCl, 5 mM DTT, 2% glycerol, pH: 7.5
Experiment: SAXS data collected at Xenocs BioXolver L with MetalJet, Département de Biochimie, Université de Montréal on 2019 Oct 22
Structural analyses of the group A flavin-dependent monooxygenase PieE reveal a sliding FAD cofactor conformation bridging OUT and IN conformations. J Biol Chem (2020)
...Zhu X, Barma J, Pascal JM, Couture M, Zhang C, Shi R
RgGuinier 4.8 nm
Dmax 13.2 nm
VolumePorod 624 nm3

SASDRG2 – Ligand free Xenosiderophore Utilization System B (XusB)

DUF4374 domain-containing protein experimental SAS data
Sample: DUF4374 domain-containing protein monomer, 46 kDa Bacteroides thetaiotaomicron (strain … protein
Buffer: 20 mM Tris 150 mM NaCl, pH: 8
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2021 May 9
Iron acquisition by a commensal bacterium modifies host nutritional immunity during Salmonella infection. Cell Host Microbe 31(10):1639-1654.e10 (2023)
...Zhu W
RgGuinier 2.3 nm
Dmax 7.4 nm
VolumePorod 74 nm3

SASDRH2 – Ligand bound Xenosiderophore Utilization System B (XusB)

DUF4374 domain-containing protein experimental SAS data
Sample: DUF4374 domain-containing protein monomer, 46 kDa Bacteroides thetaiotaomicron (strain … protein
Buffer: 20 mM Tris 150 mM NaCl, pH: 8
Experiment: SAXS data collected at 12-ID-B, Advanced Photon Source (APS), Argonne National Laboratory on 2021 May 9
Iron acquisition by a commensal bacterium modifies host nutritional immunity during Salmonella infection. Cell Host Microbe 31(10):1639-1654.e10 (2023)
...Zhu W
RgGuinier 2.4 nm
Dmax 7.4 nm
VolumePorod 77 nm3

SASDUS3 – Dark-adapted photocobilin diguanylate cyclase fusion from Acidimicrobiaceae bacterium

GGDEF domain-containing protein experimental SAS data
DAMMIF model
Sample: GGDEF domain-containing protein dimer, 132 kDa Acidimicrobiaceae bacterium protein
Buffer: 20 mM HEPES, 150 mM NaCl, pH: 6.8
Experiment: SAXS data collected at BM29, ESRF on 2022 Jan 21
Photocobilins integrate B(12) and bilin photochemistry for enzyme control. Nat Commun 15(1):2740 (2024)
...Zhu L, Cliff MJ, Yan C, Schirò G, Weik M, Sakuma M, Levy CW, Leys D, Heyes DJ, Scrutton NS
RgGuinier 4.1 nm
Dmax 14.9 nm
VolumePorod 194 nm3

SASDUT3 – Light-adapted photocobilin diguanylate cyclase fusion from Acidimicrobiaceae bacterium

GGDEF domain-containing protein experimental SAS data
DAMMIF model
Sample: GGDEF domain-containing protein dimer, 132 kDa Acidimicrobiaceae bacterium protein
Buffer: 20 mM HEPES, 150 mM NaCl, pH: 6.8
Experiment: SAXS data collected at BM29, ESRF on 2022 Jan 21
Photocobilins integrate B(12) and bilin photochemistry for enzyme control. Nat Commun 15(1):2740 (2024)
...Zhu L, Cliff MJ, Yan C, Schirò G, Weik M, Sakuma M, Levy CW, Leys D, Heyes DJ, Scrutton NS
RgGuinier 5.0 nm
Dmax 18.5 nm
VolumePorod 170 nm3

SASDLE5 – RORg2 bound to a Classic-RORgamma Response Element

Retinoid-related orphan receptor-gammaClassic-RORgamma Response Element experimental SAS data
RORg2 bound to a Classic-RORgamma Response Element Rg histogram
Sample: Retinoid-related orphan receptor-gamma monomer, 56 kDa Homo sapiens protein
Classic-RORgamma Response Element dimer, 19 kDa Homo sapiens DNA
Buffer: 25 mM HEPES, 150 mM TCEP, 2% Glycerol, 5 mM DTT, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2020 Nov 20
Conformational Changes of RORγ During Response Element Recognition and Coregulator Engagement Journal of Molecular Biology :167258 (2021)
...Zhu Y, Novick S, Garcia-Ordonez R, Doebelin C, He Y, Ra Chang M, Kamenecka T, Edwards D, Griffin P
RgGuinier 5.5 nm
Dmax 22.9 nm
VolumePorod 132 nm3

SASDLF5 – RORg2 bound to a Variant-RORgamma Response Element

Retinoid-related orphan receptor-gammaVariant-RORgamma Response Element experimental SAS data
RORg2 bound to a Variant-RORgamma Response Element Rg histogram
Sample: Retinoid-related orphan receptor-gamma monomer, 56 kDa Homo sapiens protein
Variant-RORgamma Response Element dimer, 18 kDa Homo sapiens DNA
Buffer: 25 mM HEPES, 150 mM TCEP, 2% Glycerol, 5 mM DTT, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2020 Nov 20
Conformational Changes of RORγ During Response Element Recognition and Coregulator Engagement Journal of Molecular Biology :167258 (2021)
...Zhu Y, Novick S, Garcia-Ordonez R, Doebelin C, He Y, Ra Chang M, Kamenecka T, Edwards D, Griffin P
RgGuinier 4.4 nm
Dmax 22.1 nm
VolumePorod 112 nm3

SASDCL6 – Lys63-linked dimer ubiquitin

Polyubiquitin-C experimental SAS data
Polyubiquitin-C Kratky plot
Sample: Polyubiquitin-C dimer, 17 kDa Homo sapiens protein
Buffer: 100mM NaCl, 10mM sodium acetate, pH: 6
Experiment: SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2016 Mar 24
Lys63-linked ubiquitin chain adopts multiple conformational states for specific target recognition. Elife 4 (2015)
...Zhu WK, Guo DC, Zhang WP, Liu ML, Tang C
RgGuinier 2.1 nm
Dmax 6.5 nm
VolumePorod 24 nm3

SASDB27 – Chimeric EcRHH-RcPutA: The E.coli Proline utilization A RHH domain fused to R.capsulatus PutA

Proline utilization A experimental SAS data
Proline utilization A Kratky plot
Sample: Proline utilization A dimer, 251 kDa Escherchia coli, Rhodobacter … protein
Buffer: 50 mM Tris, 200 mM NaCl, 0.5 mM Tris(3-hydroxypropyl)phosphine, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2012 Oct 16
Engineering a trifunctional proline utilization A chimaera by fusing a DNA-binding domain to a bifunctional PutA. Biosci Rep 36(6) (2016)
...Zhu W, Singh H, Tanner JJ, Becker DF
RgGuinier 5.2 nm
Dmax 18.3 nm
VolumePorod 308 nm3

SASDCG7 – Lys63-linked diubiquitin at pH7.4

Polyubiquitin-C experimental SAS data
Polyubiquitin-C Kratky plot
Sample: Polyubiquitin-C dimer, 17 kDa Homo sapiens protein
Buffer: 20mM HEPES, 150mM NaCl, pH: 7.4
Experiment: SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2016 Mar 24
Characterizing Protein Dynamics with Integrative Use of Bulk and Single-Molecule Techniques. Biochemistry 57(3):305-313 (2018)
Liu Z, Gong Z, Cao Y, Ding YH, Dong MQ, Lu YB, Zhang WP, Tang C
RgGuinier 2.0 nm
Dmax 7.0 nm
VolumePorod 22 nm3

SASDK48 – Histidine kinase AdeS - DHp-CA Domain

Histidine kinase experimental SAS data
MULTIFOXS model
Sample: Histidine kinase dimer, 51 kDa Acinetobacter baumannii protein
Buffer: 20 mM Tris, 150 mM NaCl, pH: 7.4
Experiment: SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2018 Apr 21
Proteolysis and multimerization regulate signaling along the two-component regulatory system AdeRS. iScience 24(5):102476 (2021)
...Zhu L, Felix J, Wu D, Wu K, Gutsche I, Wu Y, Hwang PM, She J, Wen Y
RgGuinier 2.8 nm
Dmax 9.1 nm
VolumePorod 85 nm3

SASDK58 – Histidine kinase AdeS - cytoplasmic domain

Histidine kinase experimental SAS data
OTHER model
Sample: Histidine kinase hexamer, 186 kDa Acinetobacter baumannii protein
Buffer: 20 mM Tris, 150 mM NaCl, pH: 7.4
Experiment: SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2019 Jun 19
Proteolysis and multimerization regulate signaling along the two-component regulatory system AdeRS. iScience 24(5):102476 (2021)
...Zhu L, Felix J, Wu D, Wu K, Gutsche I, Wu Y, Hwang PM, She J, Wen Y
RgGuinier 4.6 nm
Dmax 16.3 nm
VolumePorod 378 nm3

SASDHP8 – Pentafunctional AROM polypeptide from Chaetomium thermophilum

Pentafunctional AROM polypeptide experimental SAS data
Pentafunctional AROM polypeptide Kratky plot
Sample: Pentafunctional AROM polypeptide dimer, 345 kDa Chaetomium thermophilum protein
Buffer: 20 mM HEPES, 150 mM NaCl. 2 mM TCEP, 1% sucrose, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2015 Nov 22
Architecture and functional dynamics of the pentafunctional AROM complex Nature Chemical Biology (2020)
...Zhu H, Hartmann M
RgGuinier 5.4 nm
Dmax 17.5 nm
VolumePorod 623 nm3

SASDQF9 – GRP94 protein (Endoplasmin)

Endoplasmin experimental SAS data
Endoplasmin Kratky plot
Sample: Endoplasmin dimer, 169 kDa Mus musculus protein
Buffer: 25 mM HEPES, 200 mM NaCl, 1 mM TCEP, pH: 8
Experiment: SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2018 Jul 11
Visualization of conformational transition of GRP94 in solution. Life Sci Alliance 7(2) (2024)
...Zhu R, Zhu M, Wang Q, Li N, Yang B
RgGuinier 5.6 nm
Dmax 24.0 nm
VolumePorod 260 nm3

SASDQG9 – GRP94 protein (Endoplasmin) bound to ADP

Endoplasmin experimental SAS data
Endoplasmin Kratky plot
Sample: Endoplasmin dimer, 169 kDa Mus musculus protein
Buffer: 25 mM HEPES, 200 mM NaCl, 1 mM TCEP, pH: 8
Experiment: SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2018 Jul 11
Visualization of conformational transition of GRP94 in solution. Life Sci Alliance 7(2) (2024)
...Zhu R, Zhu M, Wang Q, Li N, Yang B
RgGuinier 5.7 nm
Dmax 24.0 nm
VolumePorod 274 nm3

SASDQH9 – GRP94 protein (Endoplasmin) bound to AMP-PNP

Endoplasmin experimental SAS data
Endoplasmin Kratky plot
Sample: Endoplasmin dimer, 169 kDa Mus musculus protein
Buffer: 25 mM HEPES, 200 mM NaCl, 1 mM TCEP, pH: 8
Experiment: SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2018 Jul 11
Visualization of conformational transition of GRP94 in solution. Life Sci Alliance 7(2) (2024)
...Zhu R, Zhu M, Wang Q, Li N, Yang B
RgGuinier 5.5 nm
Dmax 24.5 nm
VolumePorod 260 nm3

SASDEP9 – Cyclic GMP-AMP synthase (cGAS)

Cyclic GMP-AMP synthase experimental SAS data
Cyclic GMP-AMP synthase (cGAS) Rg histogram
Sample: Cyclic GMP-AMP synthase monomer, 61 kDa Homo sapiens protein
Buffer: 20 mM HEPES, pH: 7.4
Experiment: SAXS data collected at EMBL P12, PETRA III on 2017 Apr 25
cGAS facilitates sensing of extracellular cyclic dinucleotides to activate innate immunity. EMBO Rep (2019)
...Zhu C, Koehler AB, Oberbeck-Mueller D, Hahnke K, Klemm M, Guhlich-Bornhof U, Ge B, Tuukkanen A, Kolbe M, Dorhoi A, Kaufmann SH
RgGuinier 3.1 nm
Dmax 12.7 nm
VolumePorod 110 nm3

SASDEQ9 – Cyclic GMP-AMP synthase (cGAS) with cyclic guanosine monophosphate–adenosine monophosphate (2'3'-cGAMP)

Cyclic GMP-AMP synthase2'-O,5'-O-((adenosine-3'-O,5'-O-diyl)bisphosphinico)guanosine experimental SAS data
Cyclic GMP-AMP synthase (cGAS) with cyclic guanosine monophosphate–adenosine monophosphate (2'3'-cGAMP) Rg histogram
Sample: Cyclic GMP-AMP synthase dimer, 123 kDa Homo sapiens protein
2'-O,5'-O-((adenosine-3'-O,5'-O-diyl)bisphosphinico)guanosine dimer, 1 kDa
Buffer: 20 mM HEPES, pH: 7.4
Experiment: SAXS data collected at EMBL P12, PETRA III on 2017 Apr 25
cGAS facilitates sensing of extracellular cyclic dinucleotides to activate innate immunity. EMBO Rep (2019)
...Zhu C, Koehler AB, Oberbeck-Mueller D, Hahnke K, Klemm M, Guhlich-Bornhof U, Ge B, Tuukkanen A, Kolbe M, Dorhoi A, Kaufmann SH
RgGuinier 3.9 nm
Dmax 14.1 nm
VolumePorod 127 nm3

SASDH38 – Wildtype preQ1 riboswitch in Bacillus subtilis, apo-state - Bsu-WT-apo

wildtype preQ1 riboswitch in Bacillus subtilis experimental SAS data
wildtype preQ1 riboswitch in Bacillus subtilis Kratky plot
Sample: wildtype preQ1 riboswitch in Bacillus subtilis monomer, 11 kDa Bacillus subtilis RNA
Buffer: 50 mM potassium phosphate, 2 mM MgCl2, 50 mM KCl, pH: 6.5
Experiment: SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2018 Mar 23
Hierarchical Conformational Dynamics Confers Thermal Adaptability to preQ1 RNA Riboswitches. J Mol Biol 432(16):4523-4543 (2020)
...Zhu YL, Xiao Y, Tang C
RgGuinier 2.6 nm
Dmax 10.5 nm
VolumePorod 20 nm3

SASDH48 – Wildtype preQ1 riboswitch in Bacillus subtilis, holo-state - Bsu-WT-holo

wildtype preQ1 riboswitch in Bacillus subtilis experimental SAS data
wildtype preQ1 riboswitch in Bacillus subtilis Kratky plot
Sample: wildtype preQ1 riboswitch in Bacillus subtilis monomer, 11 kDa Bacillus subtilis RNA
Buffer: 50 mM potassium phosphate, 2 mM MgCl2, 50 mM KCl, pH: 6.5
Experiment: SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2018 Mar 23
Hierarchical Conformational Dynamics Confers Thermal Adaptability to preQ1 RNA Riboswitches. J Mol Biol 432(16):4523-4543 (2020)
...Zhu YL, Xiao Y, Tang C
RgGuinier 2.0 nm
Dmax 9.0 nm
VolumePorod 16 nm3

SASDH58 – C15 deletion preQ1 riboswitch in Bacillus subtilis, apo-state - Bsu-C15d-apo

C15 deletion preQ1 riboswitch in Bacillus subtilis experimental SAS data
C15 deletion preQ1 riboswitch in Bacillus subtilis Kratky plot
Sample: C15 deletion preQ1 riboswitch in Bacillus subtilis monomer, 11 kDa Bacillus subtilis RNA
Buffer: 50 mM potassium phosphate, 2 mM MgCl2, 50 mM KCl, pH: 6.5
Experiment: SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2018 Mar 23
Hierarchical Conformational Dynamics Confers Thermal Adaptability to preQ1 RNA Riboswitches. J Mol Biol 432(16):4523-4543 (2020)
...Zhu YL, Xiao Y, Tang C
RgGuinier 1.9 nm
Dmax 8.0 nm
VolumePorod 17 nm3

SASDH68 – C15 deletion preQ1 riboswitch in Bacillus subtilis, holo-state - Bsu-C15d-holo

C15 deletion preQ1 riboswitch in Bacillus subtilis experimental SAS data
C15 deletion preQ1 riboswitch in Bacillus subtilis Kratky plot
Sample: C15 deletion preQ1 riboswitch in Bacillus subtilis monomer, 11 kDa Bacillus subtilis RNA
Buffer: 50 mM potassium phosphate, 2 mM MgCl2, 50 mM KCl, pH: 6.5
Experiment: SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2018 Mar 23
Hierarchical Conformational Dynamics Confers Thermal Adaptability to preQ1 RNA Riboswitches. J Mol Biol 432(16):4523-4543 (2020)
...Zhu YL, Xiao Y, Tang C
RgGuinier 2.0 nm
Dmax 8.8 nm
VolumePorod 14 nm3

SASDH78 – Wildtype preQ1 riboswitch in Thermoanaerobacter tengcongensis, apo-state - Tte-WT-apo

wildtype preQ1 riboswitch in Thermoanaerobacter tengcongensis experimental SAS data
wildtype preQ1 riboswitch in Thermoanaerobacter tengcongensis Kratky plot
Sample: wildtype preQ1 riboswitch in Thermoanaerobacter tengcongensis monomer, 11 kDa Caldanaerobacter subterraneus subsp. … RNA
Buffer: 50 mM potassium phosphate, 2 mM MgCl2, 50 mM KCl, pH: 6.5
Experiment: SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2018 Mar 23
Hierarchical Conformational Dynamics Confers Thermal Adaptability to preQ1 RNA Riboswitches. J Mol Biol 432(16):4523-4543 (2020)
...Zhu YL, Xiao Y, Tang C
RgGuinier 1.6 nm
Dmax 6.7 nm
VolumePorod 12 nm3

SASDH88 – Wildtype preQ1 riboswitch in Thermoanaerobacter tengcongensis, holo-state - Tte-WT-holo

wildtype preQ1 riboswitch in Thermoanaerobacter tengcongensis experimental SAS data
wildtype preQ1 riboswitch in Thermoanaerobacter tengcongensis Kratky plot
Sample: wildtype preQ1 riboswitch in Thermoanaerobacter tengcongensis monomer, 11 kDa Caldanaerobacter subterraneus subsp. … RNA
Buffer: 50 mM potassium phosphate, 2 mM MgCl2, 50 mM KCl, pH: 6.5
Experiment: SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2018 Mar 23
Hierarchical Conformational Dynamics Confers Thermal Adaptability to preQ1 RNA Riboswitches. J Mol Biol 432(16):4523-4543 (2020)
...Zhu YL, Xiao Y, Tang C
RgGuinier 1.6 nm
Dmax 7.2 nm
VolumePorod 13 nm3

SASDHB8 – A14 insertion preQ1 riboswitch in Thermoanaerobacter tengcongensis, apo-state - Tte-A14'-apo

A14 insertion preQ1 riboswitch in Thermoanaerobacter tengcongensis experimental SAS data
A14 insertion preQ1 riboswitch in Thermoanaerobacter tengcongensis Kratky plot
Sample: A14 insertion preQ1 riboswitch in Thermoanaerobacter tengcongensis monomer, 11 kDa Caldanaerobacter subterraneus subsp. … RNA
Buffer: 50 mM potassium phosphate, 2 mM MgCl2, 50 mM KCl, pH: 6.5
Experiment: SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2018 Mar 23
Hierarchical Conformational Dynamics Confers Thermal Adaptability to preQ1 RNA Riboswitches. J Mol Biol 432(16):4523-4543 (2020)
...Zhu YL, Xiao Y, Tang C
RgGuinier 1.9 nm
Dmax 9.0 nm
VolumePorod 14 nm3

SASDHC8 – A14 insertion preQ1 riboswitch in Thermoanaerobacter tengcongensis, holo-state - Tte-A14'-holo

A14 insertion preQ1 riboswitch in Thermoanaerobacter tengcongensis experimental SAS data
A14 insertion preQ1 riboswitch in Thermoanaerobacter tengcongensis Kratky plot
Sample: A14 insertion preQ1 riboswitch in Thermoanaerobacter tengcongensis monomer, 11 kDa Caldanaerobacter subterraneus subsp. … RNA
Buffer: 50 mM potassium phosphate, 2 mM MgCl2, 50 mM KCl, pH: 6.5
Experiment: SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2018 Mar 23
Hierarchical Conformational Dynamics Confers Thermal Adaptability to preQ1 RNA Riboswitches. J Mol Biol 432(16):4523-4543 (2020)
...Zhu YL, Xiao Y, Tang C
RgGuinier 1.8 nm
Dmax 12.0 nm
VolumePorod 16 nm3

SASDH98 – Wildtype preQ1 riboswitch in Thermoanaerobacter tengcongensis, apo-state high-temperature sampling - Tte-WT-apo-HT

wildtype preQ1 riboswitch in Thermoanaerobacter tengcongensis experimental SAS data
wildtype preQ1 riboswitch in Thermoanaerobacter tengcongensis Kratky plot
Sample: wildtype preQ1 riboswitch in Thermoanaerobacter tengcongensis monomer, 11 kDa Caldanaerobacter subterraneus subsp. … RNA
Buffer: 50 mM potassium phosphate, 2 mM MgCl2, 50 mM KCl, pH: 6.5
Experiment: SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2018 Mar 23
Hierarchical Conformational Dynamics Confers Thermal Adaptability to preQ1 RNA Riboswitches. J Mol Biol 432(16):4523-4543 (2020)
...Zhu YL, Xiao Y, Tang C
RgGuinier 1.7 nm
Dmax 7.0 nm
VolumePorod 11 nm3

SASDHA8 – Wildtype preQ1 riboswitch in Thermoanaerobacter tengcongensis, holo-state high-temperature sampling - Tte-WT-holo-HT

wildtype preQ1 riboswitch in Thermoanaerobacter tengcongensis experimental SAS data
wildtype preQ1 riboswitch in Thermoanaerobacter tengcongensis Kratky plot
Sample: wildtype preQ1 riboswitch in Thermoanaerobacter tengcongensis monomer, 11 kDa Caldanaerobacter subterraneus subsp. … RNA
Buffer: 50 mM potassium phosphate, 2 mM MgCl2, 50 mM KCl, pH: 6.5
Experiment: SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2018 Mar 23
Hierarchical Conformational Dynamics Confers Thermal Adaptability to preQ1 RNA Riboswitches. J Mol Biol 432(16):4523-4543 (2020)
...Zhu YL, Xiao Y, Tang C
RgGuinier 1.5 nm
Dmax 6.5 nm
VolumePorod 10 nm3

SASDHD8 – A14 insertion preQ1 riboswitch in Thermoanaerobacter tengcongensis, apo-state high-temperature sampling - Tte-A14'-apo-HT

A14 insertion preQ1 riboswitch in Thermoanaerobacter tengcongensis experimental SAS data
A14 insertion preQ1 riboswitch in Thermoanaerobacter tengcongensis Kratky plot
Sample: A14 insertion preQ1 riboswitch in Thermoanaerobacter tengcongensis monomer, 11 kDa Caldanaerobacter subterraneus subsp. … RNA
Buffer: 50 mM potassium phosphate, 2 mM MgCl2, 50 mM KCl, pH: 6.5
Experiment: SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2018 Mar 23
Hierarchical Conformational Dynamics Confers Thermal Adaptability to preQ1 RNA Riboswitches. J Mol Biol 432(16):4523-4543 (2020)
...Zhu YL, Xiao Y, Tang C
RgGuinier 1.8 nm
Dmax 7.5 nm
VolumePorod 13 nm3

SASDHE8 – A14 insertion preQ1 riboswitch in Thermoanaerobacter tengcongensis, holo-state high-temperature sampling - Tte-A14'-holo-HT

A14 insertion preQ1 riboswitch in Thermoanaerobacter tengcongensis experimental SAS data
A14 insertion preQ1 riboswitch in Thermoanaerobacter tengcongensis Kratky plot
Sample: A14 insertion preQ1 riboswitch in Thermoanaerobacter tengcongensis monomer, 11 kDa Caldanaerobacter subterraneus subsp. … RNA
Buffer: 50 mM potassium phosphate, 2 mM MgCl2, 50 mM KCl, pH: 6.5
Experiment: SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2018 Mar 23
Hierarchical Conformational Dynamics Confers Thermal Adaptability to preQ1 RNA Riboswitches. J Mol Biol 432(16):4523-4543 (2020)
...Zhu YL, Xiao Y, Tang C
RgGuinier 1.9 nm
Dmax 8.8 nm
VolumePorod 14 nm3