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31 hits found for Fan

SASDK92 – Interferon-activable protein 204 from Mus musculus (Mouse) amino-acids 215-619

Interferon-activable protein 204 experimental SAS data
CHIMERA model
Sample: Interferon-activable protein 204 monomer, 47 kDa Mus musculus protein
Buffer: 20 mM HEPES, 100 mM KCl, pH: 7.4
Experiment: SAXS data collected at X9A, National Synchrotron Light Source (NSLS) on 2013 Mar 14
Structural mechanism of DNA recognition by the p204 HIN domain. Nucleic Acids Res (2021)
Fan X, Jiang J, Zhao D, Chen F, Ma H, Smith P, Unterholzner L, Xiao TS, Jin T
RgGuinier 3.1 nm
Dmax 9.5 nm
VolumePorod 28 nm3

SASDNH3 – HIV-1 reverse transcriptase L289K mutation at 1 mg/mL

Gag-Pol polyprotein (HIV-1 reverse transcriptase C38V/C280S, L289K truncated to 1 - 556) experimental SAS data
Gag-Pol polyprotein (HIV-1 reverse transcriptase C38V/C280S, L289K truncated to 1 - 556) Kratky plot
Sample: Gag-Pol polyprotein (HIV-1 reverse transcriptase C38V/C280S, L289K truncated to 1 - 556) monomer, 65 kDa Human immunodeficiency virus … protein
Buffer: 50 mM Bis-Tris pH 6.8, 100 mM NaCl, 1% glycerol, 0.02% w/v NaN3, pH: 6.8
Experiment: SAXS data collected at 12-ID-B SAXS/WAXS, Advanced Photon Source (APS), Argonne National Laboratory on 2019 Jun 20
Relative domain orientation of the L289K HIV ‐1 reverse transcriptase monomer Protein Science 31(5) (2022)
...Fan L, Sluis‐Cremer N, Wang Y, Ishima R
RgGuinier 3.2 nm
Dmax 10.7 nm
VolumePorod 91 nm3

SASDNJ3 – HIV-1 reverse transcriptase L289K mutation at 2 mg/mL

Gag-Pol polyprotein (HIV-1 reverse transcriptase C38V/C280S, L289K truncated to 1 - 556) experimental SAS data
Gag-Pol polyprotein (HIV-1 reverse transcriptase C38V/C280S, L289K truncated to 1 - 556) Kratky plot
Sample: Gag-Pol polyprotein (HIV-1 reverse transcriptase C38V/C280S, L289K truncated to 1 - 556) monomer, 65 kDa Human immunodeficiency virus … protein
Buffer: 50 mM Bis-Tris pH 6.8, 100 mM NaCl, 1% glycerol, 0.02% w/v NaN3, pH: 6.8
Experiment: SAXS data collected at 12-ID-B SAXS/WAXS, Advanced Photon Source (APS), Argonne National Laboratory on 2019 Jun 20
Relative domain orientation of the L289K HIV ‐1 reverse transcriptase monomer Protein Science 31(5) (2022)
...Fan L, Sluis‐Cremer N, Wang Y, Ishima R
RgGuinier 3.2 nm
Dmax 10.8 nm
VolumePorod 91 nm3

SASDNK3 – HIV-1 reverse transcriptase L289K mutation at 4.3 mg/mL

Gag-Pol polyprotein (HIV-1 reverse transcriptase C38V/C280S, L289K truncated to 1 - 556) experimental SAS data
Gag-Pol polyprotein (HIV-1 reverse transcriptase C38V/C280S, L289K truncated to 1 - 556) Kratky plot
Sample: Gag-Pol polyprotein (HIV-1 reverse transcriptase C38V/C280S, L289K truncated to 1 - 556) monomer, 65 kDa Human immunodeficiency virus … protein
Buffer: 50 mM Bis-Tris pH 6.8, 100 mM NaCl, 1% glycerol, 0.02% w/v NaN3, pH: 6.8
Experiment: SAXS data collected at 12-ID-B SAXS/WAXS, Advanced Photon Source (APS), Argonne National Laboratory on 2019 Jun 20
Relative domain orientation of the L289K HIV ‐1 reverse transcriptase monomer Protein Science 31(5) (2022)
...Fan L, Sluis‐Cremer N, Wang Y, Ishima R
RgGuinier 3.2 nm
Dmax 10.7 nm
VolumePorod 93 nm3

SASDNL3 – HIV-1 reverse transcriptase L289K mutation (extrapolated to zero concentration)

Gag-Pol polyprotein (HIV-1 reverse transcriptase C38V/C280S, L289K truncated to 1 - 556) experimental SAS data
BUNCH model
Sample: Gag-Pol polyprotein (HIV-1 reverse transcriptase C38V/C280S, L289K truncated to 1 - 556) monomer, 65 kDa Human immunodeficiency virus … protein
Buffer: 50 mM Bis-Tris pH 6.8, 100 mM NaCl, 1% glycerol, 0.02% w/v NaN3, pH: 6.8
Experiment: SAXS data collected at 12-ID-B SAXS/WAXS, Advanced Photon Source (APS), Argonne National Laboratory on 2021 Jun 20
Relative domain orientation of the L289K HIV ‐1 reverse transcriptase monomer Protein Science 31(5) (2022)
...Fan L, Sluis‐Cremer N, Wang Y, Ishima R
RgGuinier 3.2 nm
Dmax 11.1 nm
VolumePorod 90 nm3

SASDVW3 – Lipoprotein NlpI dimer bound to two asymmetrical murein DD-endopeptidase mMepS dimers at pH 7.0

Lipoprotein NlpIMurein DD-endopeptidase MepS/Murein LD-carboxypeptidase experimental SAS data
PYMOL model
Sample: Lipoprotein NlpI dimer, 63 kDa Escherichia coli (strain … protein
Murein DD-endopeptidase MepS/Murein LD-carboxypeptidase tetramer, 73 kDa Escherichia coli (strain … protein
Buffer: 0.2 M Na/K phosphate pH 7.0, 2 mM 2-mercaptoethanol, pH: 7
Experiment: SAXS data collected at TPS13A, NSRRC on 2023 Sep 7
Structural basis for recruitment of peptidoglycan endopeptidase MepS by lipoprotein NlpI. Nat Commun 15(1):5461 (2024)
...Fan YS, Wang SW, Tseng HC, Huang SJ, Chang YY, Jeng US, Chang CI, Tzeng SR
RgGuinier 3.5 nm
Dmax 11.5 nm
VolumePorod 123 nm3

SASDG54 – Human macrophage mannose receptor 1 protein

Macrophage mannose receptor 1 experimental SAS data
ITASSER model
Sample: Macrophage mannose receptor 1 dimer, 315 kDa Mouse myeloma cell … protein
Buffer: 50mM Hepes, 100mM NaCl, 1mM DTT, pH: 7
Experiment: SAXS data collected at 12-ID-B SAXS/WAXS, Advanced Photon Source (APS), Argonne National Laboratory on 2016 Apr 15
Mannose receptor (CD206) activation in tumor-associated macrophages enhances adaptive and innate antitumor immune responses. Sci Transl Med 12(530) (2020)
...Fan L, Hu X, Simeonov A, Pate N, Abu-Asab M, Ferrer M, Southall N, Ock CY, Zhao Y, Lopez H, Kozlov S, de Val N, Yates CC, Baljinnyam B, Marugan J, Rudloff U
RgGuinier 7.9 nm
Dmax 30.1 nm
VolumePorod 584 nm3

SASDMM4 – Hepatitis C virus 5BSL3.2 RNA subdomain

5BSL3.2 experimental SAS data
DAMFILT model
Sample: 5BSL3.2 monomer, 15 kDa Hepatitis C virus … RNA
Buffer: 10 mM Tris-HCl, 0.1 mM EDTA, pH: 7
Experiment: SAXS data collected at Rigaku BioSAXS-1000, NIDDK, NIH on 2019 Jun 2
The low-resolution structural models of hepatitis C virus RNA subdomain 5BSL3.2 and its distal complex with domain 3'X point to conserved regulatory mechanisms within the Flaviviridae family. Nucleic Acids Res (2022)
...Fan L, Szewczyk MP, Wang YX, Gallego J
RgGuinier 2.5 nm
Dmax 7.6 nm
VolumePorod 29 nm3

SASDMN4 – Hepatitis C virus 5BSL3.2 RNA subdomain

5BSL3.2 experimental SAS data
DAMFILT model
Sample: 5BSL3.2 monomer, 15 kDa Hepatitis C virus … RNA
Buffer: 10 mM Tris-HCl, 6 mM MgCl2, pH: 7
Experiment: SAXS data collected at Rigaku BioSAXS-1000, NIDDK, NIH on 2019 Jun 2
The low-resolution structural models of hepatitis C virus RNA subdomain 5BSL3.2 and its distal complex with domain 3'X point to conserved regulatory mechanisms within the Flaviviridae family. Nucleic Acids Res (2022)
...Fan L, Szewczyk MP, Wang YX, Gallego J
RgGuinier 2.1 nm
Dmax 7.0 nm
VolumePorod 22 nm3

SASDMP4 – Hepatitis C virus RNA Domain 3'X mutant

Domain 3'X mutant experimental SAS data
DAMFILT model
Sample: Domain 3'X mutant monomer, 32 kDa Hepatitis C virus … RNA
Buffer: 10 mM Tris-HCl, 0.1 mM EDTA, pH: 7
Experiment: SAXS data collected at Rigaku BioSAXS-1000, NIDDK, NIH on 2019 Jun 2
The low-resolution structural models of hepatitis C virus RNA subdomain 5BSL3.2 and its distal complex with domain 3'X point to conserved regulatory mechanisms within the Flaviviridae family. Nucleic Acids Res (2022)
...Fan L, Szewczyk MP, Wang YX, Gallego J
RgGuinier 4.1 nm
Dmax 14.7 nm
VolumePorod 70 nm3

SASDMQ4 – Hepatitis C virus RNA Domain 3'X mutant

Domain 3'X mutant experimental SAS data
DAMFILT model
Sample: Domain 3'X mutant monomer, 32 kDa Hepatitis C virus … RNA
Buffer: 10 mM Tris-HCl, 6 mM MgCl2, pH: 7
Experiment: SAXS data collected at 12-ID-B SAXS/WAXS, Advanced Photon Source (APS), Argonne National Laboratory on 2019 Jun 2
The low-resolution structural models of hepatitis C virus RNA subdomain 5BSL3.2 and its distal complex with domain 3'X point to conserved regulatory mechanisms within the Flaviviridae family. Nucleic Acids Res (2022)
...Fan L, Szewczyk MP, Wang YX, Gallego J
RgGuinier 3.3 nm
Dmax 14.2 nm
VolumePorod 50 nm3

SASDMR4 – Hepatitis C virus RNA Domain 3'X mutant - Subdomain 5BSL3.2 complex

Domain 3'X mutant - 5BSL3.2 complex experimental SAS data
DAMFILT model
Sample: Domain 3'X mutant - 5BSL3.2 complex monomer, 42 kDa Hepatitis C virus … RNA
Buffer: 10 mM Tris-HCl, 6 mM MgCl2, pH: 7
Experiment: SAXS data collected at Rigaku BioSAXS-1000, NIDDK, NIH on 2019 Jun 2
The low-resolution structural models of hepatitis C virus RNA subdomain 5BSL3.2 and its distal complex with domain 3'X point to conserved regulatory mechanisms within the Flaviviridae family. Nucleic Acids Res (2022)
...Fan L, Szewczyk MP, Wang YX, Gallego J
RgGuinier 4.2 nm
Dmax 17.0 nm
VolumePorod 88 nm3

SASDQG7 – Thermoanearobacter tengcongensis (Tte) fecB RNA riboswitch aptamer domain (rCbl)

Thermoanearobacter tengcongensis (Tte) fecB riboswitch aptamer domain experimental SAS data
OTHER model
Sample: Thermoanearobacter tengcongensis (Tte) fecB riboswitch aptamer domain , 68 kDa marine metagenome RNA
Buffer: 50 mM MES pH 6.0, 10 mM KCl, 1 mM MgCl2, pH: 6
Experiment: SAXS data collected at 12-ID-B SAXS/WAXS, Advanced Photon Source (APS), Argonne National Laboratory on 2021 Apr 18
Visualizing RNA conformational and architectural heterogeneity in solution. Nat Commun 14(1):714 (2023)
...Fan L, Yu P, Tarosov SG, Stagno JR, Ma B, Nussinov R, Rein A, Zhang J, Wang YX
RgGuinier 5.9 nm
Dmax 20.7 nm
VolumePorod 206 nm3

SASDQH7 – Thermoanearobacter tengcongensis (Tte) fecB RNA riboswitch aptamer domain (rCbl) in the presence of coenzyme B12

Thermoanearobacter tengcongensis (Tte) fecB riboswitch aptamer domain experimental SAS data
OTHER model
Sample: Thermoanearobacter tengcongensis (Tte) fecB riboswitch aptamer domain , 68 kDa marine metagenome RNA
Buffer: 50 mM MES pH 6.0, 10 mM KCl, 1 mM MgCl2, 4-18 μM coenzyme B12 ligand, pH: 6
Experiment: SAXS data collected at 12-ID-B SAXS/WAXS, Advanced Photon Source (APS), Argonne National Laboratory on 2021 Apr 18
Visualizing RNA conformational and architectural heterogeneity in solution. Nat Commun 14(1):714 (2023)
...Fan L, Yu P, Tarosov SG, Stagno JR, Ma B, Nussinov R, Rein A, Zhang J, Wang YX
RgGuinier 5.7 nm
Dmax 19.7 nm
VolumePorod 230 nm3

SASDKD8 – LuxR family transcriptional regulator, SmcR

LuxR family transcriptional regulator experimental SAS data
CHIMERA model
Sample: LuxR family transcriptional regulator , 52 kDa Vibrio vulnificus protein
Buffer: 200 mM NaCl, 25 mM Tris, pH: 7.5
Experiment: SAXS data collected at 12-ID-B SAXS/WAXS, Advanced Photon Source (APS), Argonne National Laboratory on 2020 Aug 8
The DNA binding domain of the Vibrio vulnificus SmcR transcription factor is flexible and binds diverse DNA sequences. Nucleic Acids Res 49(10):5967-5984 (2021)
...Fan L, Wang YX, Gonzalez-Gutierrez G, van Kessel JC
RgGuinier 3.1 nm
Dmax 12.0 nm
VolumePorod 67 nm3

SASDKE8 – LuxR family transcriptional regulator, SmcR N55I mutant

LuxR family transcriptional regulator, N55I experimental SAS data
CHIMERA model
Sample: LuxR family transcriptional regulator, N55I , 52 kDa Vibrio vulnificus protein
Buffer: 200 mM NaCl, 25 mM Tris, 1 mM DTT, 0.5 mM EDTA, pH: 7.5
Experiment: SAXS data collected at 12-ID-B SAXS/WAXS, Advanced Photon Source (APS), Argonne National Laboratory on 2020 Dec 11
The DNA binding domain of the Vibrio vulnificus SmcR transcription factor is flexible and binds diverse DNA sequences. Nucleic Acids Res 49(10):5967-5984 (2021)
...Fan L, Wang YX, Gonzalez-Gutierrez G, van Kessel JC
RgGuinier 3.0 nm
Dmax 10.1 nm
VolumePorod 45 nm3

SASDU39 – Nearly full-length monomeric Human Ubiquitin carboxyl-terminal hydrolase 8 (USP8) (7-1110)

Ubiquitin carboxyl-terminal hydrolase 8 experimental SAS data
DAMMIF model
Sample: Ubiquitin carboxyl-terminal hydrolase 8 monomer, 127 kDa Homo sapiens protein
Buffer: 25 mM Tris, 150 mM NaCl, pH: 7.5
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2022 Jun 18
Autoinhibition of ubiquitin-specific protease 8: insights into domain interactions and mechanisms of regulation Journal of Biological Chemistry :107727 (2024)
...Fan L, Harding R, Wang Y, Vacratsis P, Huang R, Zhuang Z, Tong Y
RgGuinier 8.4 nm
Dmax 31.8 nm
VolumePorod 327 nm3

SASDHL9 – Full-length HERV-K Rec response element

Full-length HERV-K Rec response element experimental SAS data
Full-length HERV-K Rec response element Kratky plot
Sample: Full-length HERV-K Rec response element monomer, 141 kDa Homo sapiens RNA
Buffer: 10mM Tris-HCl, 100mM KCl, and 0.5mM MgCl₂, pH: 8
Experiment: SAXS data collected at 12-ID-B SAXS/WAXS, Advanced Photon Source (APS), Argonne National Laboratory on 2018 Feb 10
Structural Mimicry Drives HIV-1 Rev-Mediated HERV-K Expression Journal of Molecular Biology 432(24):166711 (2020)
...Fan L, Kroupa T, McShane E, Theodore C, Yates E, Kondrup B, Ding J, Martin T, Rein A, Wang Y
RgGuinier 7.5 nm
Dmax 28.2 nm
VolumePorod 454 nm3

SASDHM9 – Truncated HERV-K Rec response element (RcRE) RNA

Truncated HERV-K Rec response element experimental SAS data
DAMFILT model
Sample: Truncated HERV-K Rec response element monomer, 102 kDa Homo sapiens RNA
Buffer: 10mM Tris-HCl, 100mM KCl, and 0.5mM MgCl₂, pH: 8
Experiment: SAXS data collected at 12-ID-B SAXS/WAXS, Advanced Photon Source (APS), Argonne National Laboratory on 2018 Jul 17
Structural Mimicry Drives HIV-1 Rev-Mediated HERV-K Expression Journal of Molecular Biology 432(24):166711 (2020)
...Fan L, Kroupa T, McShane E, Theodore C, Yates E, Kondrup B, Ding J, Martin T, Rein A, Wang Y
RgGuinier 6.1 nm
Dmax 21.8 nm
VolumePorod 322 nm3

SASDHN9 – TrΔSLIII HERV-K Rec response element (RcRE) RNA

TrΔSLIII HERV-K Rec response element experimental SAS data
DAMFILT model
Sample: TrΔSLIII HERV-K Rec response element monomer, 88 kDa Homo sapiens RNA
Buffer: 10mM Tris-HCl, 100mM KCl, and 0.5mM MgCl₂, pH: 8
Experiment: SAXS data collected at 12-ID-B SAXS/WAXS, Advanced Photon Source (APS), Argonne National Laboratory on 2018 Dec 7
Structural Mimicry Drives HIV-1 Rev-Mediated HERV-K Expression Journal of Molecular Biology 432(24):166711 (2020)
...Fan L, Kroupa T, McShane E, Theodore C, Yates E, Kondrup B, Ding J, Martin T, Rein A, Wang Y
RgGuinier 5.3 nm
Dmax 19.2 nm
VolumePorod 226 nm3

SASDHP9 – TrΔSLIIab HERV-K Rec response element (RcRE) RNA

TrΔSLIIab HERV-K Rec response element experimental SAS data
DAMFILT model
Sample: TrΔSLIIab HERV-K Rec response element monomer, 86 kDa Homo sapiens RNA
Buffer: 10mM Tris-HCl, 100mM KCl, and 0.5mM MgCl₂, pH: 8
Experiment: SAXS data collected at 12-ID-B SAXS/WAXS, Advanced Photon Source (APS), Argonne National Laboratory on 2020 Feb 21
Structural Mimicry Drives HIV-1 Rev-Mediated HERV-K Expression Journal of Molecular Biology 432(24):166711 (2020)
...Fan L, Kroupa T, McShane E, Theodore C, Yates E, Kondrup B, Ding J, Martin T, Rein A, Wang Y
RgGuinier 5.0 nm
Dmax 18.4 nm
VolumePorod 201 nm3

SASDQV9 – Nanobody1 in complex with the extracellular domain of human BCMA

Tumor necrosis factor receptor superfamily member 17Nanobody1 experimental SAS data
Tumor necrosis factor receptor superfamily member 17 Nanobody1 Kratky plot
Sample: Tumor necrosis factor receptor superfamily member 17 monomer, 6 kDa Homo sapiens protein
Nanobody1 monomer, 14 kDa protein
Buffer: 20 mM Tris, 100 mM NaCl, pH: 8
Experiment: SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2022 Aug 28
Antigen-induced chimeric antigen receptor multimerization amplifies on-tumor cytotoxicity. Signal Transduct Target Ther 8(1):445 (2023)
...Fan XH, Chen SJ, Chen S
RgGuinier 3.0 nm
Dmax 9.8 nm
VolumePorod 52 nm3

SASDQW9 – Nanobody2 in complex with the extracellular domain of human BCMA

Tumor necrosis factor receptor superfamily member 17Nanobody2 experimental SAS data
Tumor necrosis factor receptor superfamily member 17 Nanobody2 Kratky plot
Sample: Tumor necrosis factor receptor superfamily member 17 monomer, 6 kDa Homo sapiens protein
Nanobody2 monomer, 14 kDa protein
Buffer: 20 mM Tris, 100 mM NaCl, pH: 8
Experiment: SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2022 Aug 28
Antigen-induced chimeric antigen receptor multimerization amplifies on-tumor cytotoxicity. Signal Transduct Target Ther 8(1):445 (2023)
...Fan XH, Chen SJ, Chen S
RgGuinier 2.0 nm
Dmax 9.0 nm
VolumePorod 24 nm3

SASDQX9 – Tandem nanobody in complex with the extracellular domain of human BCMA

Tumor necrosis factor receptor superfamily member 17Tandem nanobody experimental SAS data
Tumor necrosis factor receptor superfamily member 17 Tandem nanobody Kratky plot
Sample: Tumor necrosis factor receptor superfamily member 17 monomer, 6 kDa Homo sapiens protein
Tandem nanobody monomer, 27 kDa protein
Buffer: 20 mM Tris, 100 mM NaCl, pH: 8
Experiment: SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2022 Aug 28
Antigen-induced chimeric antigen receptor multimerization amplifies on-tumor cytotoxicity. Signal Transduct Target Ther 8(1):445 (2023)
...Fan XH, Chen SJ, Chen S
RgGuinier 5.1 nm
Dmax 23.3 nm
VolumePorod 247 nm3

SASDBM7 – Subdomain SL1 of hepatitis C virus RNA domain 3'X at low ionic strength

Subdomain SL1 of hepatitis C virus experimental SAS data
DAMMIN model
Sample: Subdomain SL1 of hepatitis C virus monomer, 15 kDa Hepatitis C virus RNA
Buffer: 10mM Tris 0.1 mM EDTA, pH: 7
Experiment: SAXS data collected at 12-ID-B SAXS/WAXS, Advanced Photon Source (APS), Argonne National Laboratory on 2015 Nov 11
Three-dimensional structure of the 3'X-tail of hepatitis C virus RNA in monomeric and dimeric states. RNA 23(9):1465-1476 (2017)
...Fan L, Wang YX, Gallego J
RgGuinier 2.3 nm
Dmax 8.1 nm

SASDSW7 – poly(GU) RNA with 12 GU repeats

polyGU RNA - (GU)12 experimental SAS data
XPLOR-NIH model
Sample: polyGU RNA - (GU)12 monomer, 8 kDa synthetic RNA RNA
Buffer: 20 mM HEPES, 150 mM KCl, pH: 7
Experiment: SAXS data collected at 12-ID-B, Advanced Photon Source (APS), Argonne National Laboratory on 2022 Jun 10
Solution structure of poly(UG) RNA Journal of Molecular Biology :168340 (2023)
...Fan L, Henzler-Wildman K, Butcher S
RgGuinier 1.3 nm
Dmax 4.7 nm
VolumePorod 8 nm3

SASDBN7 – Subdomain SL2' of hepatitis C virus RNA domain 3'X at low ionic strength

Subdomain SL2' of hepatitis C virus domain 3'X experimental SAS data
DAMMIN model
Sample: Subdomain SL2' of hepatitis C virus domain 3'X monomer, 18 kDa Hepatitis C virus RNA
Buffer: 10mM Tris 0.1 mM EDTA, pH: 7
Experiment: SAXS data collected at 12-ID-B SAXS/WAXS, Advanced Photon Source (APS), Argonne National Laboratory on 2015 Nov 11
Three-dimensional structure of the 3'X-tail of hepatitis C virus RNA in monomeric and dimeric states. RNA 23(9):1465-1476 (2017)
...Fan L, Wang YX, Gallego J
RgGuinier 2.8 nm
Dmax 10.0 nm

SASDRT7 – poly(GU) RNA with 12 GU repeats - (GU)12 RNA

polyGU RNA - (GU)12 experimental SAS data
OTHER model
Sample: polyGU RNA - (GU)12 monomer, 8 kDa synthetic RNA RNA
Buffer: 20 mM HEPES, 150 mM KCl, pH: 7
Experiment: SAXS data collected at 12-ID-B, Advanced Photon Source (APS), Argonne National Laboratory on 2022 Jun 10
Solution structure of poly(UG) RNA Journal of Molecular Biology :168340 (2023)
...Fan L, Henzler-Wildman K, Butcher S
RgGuinier 1.4 nm
Dmax 5.1 nm
VolumePorod 11 nm3

SASDBP7 – Domain 3'X of hepatitis C virus RNA at low ionic strength

Domain 3'X of hepatitis C virus experimental SAS data
DAMMIN model
Sample: Domain 3'X of hepatitis C virus monomer, 32 kDa Hepatitis C virus RNA
Buffer: 10mM Tris 0.1 mM EDTA, pH: 7
Experiment: SAXS data collected at 12-ID-B SAXS/WAXS, Advanced Photon Source (APS), Argonne National Laboratory on 2015 Nov 11
Three-dimensional structure of the 3'X-tail of hepatitis C virus RNA in monomeric and dimeric states. RNA 23(9):1465-1476 (2017)
...Fan L, Wang YX, Gallego J
RgGuinier 3.7 nm
Dmax 14.8 nm

SASDBQ7 – Domain 3'X of hepatitis C virus RNA at higher ionic strength

Domain 3'X of hepatitis C virus experimental SAS data
DAMMIN model
Sample: Domain 3'X of hepatitis C virus dimer, 63 kDa Hepatitis C virus RNA
Buffer: 10mM Tris 0.1 mM EDTA 2 mM MgCl2 50 mM NaCl, pH: 7
Experiment: SAXS data collected at Rigaku BioSAXS-2000, Center for Cancer Research, National Cancer Institute on 2015 Nov 20
Three-dimensional structure of the 3'X-tail of hepatitis C virus RNA in monomeric and dimeric states. RNA 23(9):1465-1476 (2017)
...Fan L, Wang YX, Gallego J
RgGuinier 6.0 nm
Dmax 24.4 nm

SASDBR7 – Subdomain SL2' of hepatitis C virus RNA domain 3'X at higher ionic strength

Subdomain SL2' of hepatitis C virus domain 3'X experimental SAS data
DAMMIN model
Sample: Subdomain SL2' of hepatitis C virus domain 3'X dimer, 36 kDa Hepatitis C virus RNA
Buffer: 10mM Tris 0,1mM EDTA 2mM MgCl2, pH: 7
Experiment: SAXS data collected at 12-ID-B SAXS/WAXS, Advanced Photon Source (APS), Argonne National Laboratory on 2015 Nov 11
Three-dimensional structure of the 3'X-tail of hepatitis C virus RNA in monomeric and dimeric states. RNA 23(9):1465-1476 (2017)
...Fan L, Wang YX, Gallego J
RgGuinier 4.1 nm
Dmax 16.9 nm