Small Angle Scattering Biological Data Bank SASBDB


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91 hits found for Liu

SASDUA2 – The Z-DNA binding domains Zαβ of Z-DNA binding protein 1 (monomer)

Z-DNA-binding protein 1 experimental SAS data

Sample:	Z-DNA-binding protein 1 monomer, 18 kDa Homo sapiens protein
Buffer:	20 mM Tris, 100 mM NaCl, pH: 7.5
Experiment:	SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2018 Mar 23

ZBP1 condensate formation synergizes Z-NAs recognition and signal transduction. Cell Death Dis 15(7):487 (2024)
...Liu X, Shen Y, Huang J, Su Z, Li J

R_g^Guinier	2.1	nm
D_max	9.0	nm
Volume^Porod	19	nm³

SASDUB2 – The Z-DNA binding domains Zαβ of Z-DNA binding protein 1 (dimer)

Sample:	Z-DNA-binding protein 1 dimer, 37 kDa Homo sapiens protein
Buffer:	20 mM Tris, 100 mM NaCl, pH: 7.5
Experiment:	SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2018 Mar 23

ZBP1 condensate formation synergizes Z-NAs recognition and signal transduction. Cell Death Dis 15(7):487 (2024)
...Liu X, Shen Y, Huang J, Su Z, Li J

R_g^Guinier	3.1	nm
D_max	13.0	nm
Volume^Porod	48	nm³

SASDGF3 – Xrn1 resistance RNA1 from Zika virus

Xrn1 resistance RNA2 from Zika virus experimental SAS data

Sample:	Xrn1 resistance RNA2 from Zika virus monomer, 22 kDa Zika virus RNA
Buffer:	20mM Tris-HCl, 100mM NaCl, 5mM MgCl2, pH: 7.5
Experiment:	SAXS data collected at 12-ID-B SAXS/WAXS, Advanced Photon Source (APS), Argonne National Laboratory on 2016 Dec 9

Long non-coding subgenomic flavivirus RNAs have extended 3D structures and are flexible in solution. EMBO Rep 20(11):e47016 (2019)
...Liu ZY, Cheng ML, Ma J, Wang Y, Qin CF, Fang X

R_g^Guinier	2.4	nm
D_max	8.5	nm
Volume^Porod	34	nm³

SASDGG3 – Xrn1 resistance RNA1 from Dengue virus 2

Xrn1 resistance RNA1 from Dengue virus 2 experimental SAS data

Sample:	Xrn1 resistance RNA1 from Dengue virus 2 monomer, 21 kDa Dengue virus 2 RNA
Buffer:	20mM Tris-HCl, 100mM NaCl, 5mM MgCl2, pH: 7.5
Experiment:	SAXS data collected at 14-ID-B (BioCARS), Advanced Photon Source (APS), Argonne National Laboratory on 2016 Dec 9

Long non-coding subgenomic flavivirus RNAs have extended 3D structures and are flexible in solution. EMBO Rep 20(11):e47016 (2019)
...Liu ZY, Cheng ML, Ma J, Wang Y, Qin CF, Fang X

R_g^Guinier	2.2	nm
D_max	8.0	nm
Volume^Porod	31	nm³

SASDGH3 – Xrn1 resistance RNA1-2 from Zika virus

Xrn1 resistance RNA1-2 from Dengue virus 2 experimental SAS data

Sample:	Xrn1 resistance RNA1-2 from Dengue virus 2 monomer, 46 kDa Dengue virus 2 RNA
Buffer:	20mM Tris-HCl, 100mM NaCl, 5mM MgCl2, pH: 7.5
Experiment:	SAXS data collected at 12-ID-B SAXS/WAXS, Advanced Photon Source (APS), Argonne National Laboratory on 2017 Apr 2

Long non-coding subgenomic flavivirus RNAs have extended 3D structures and are flexible in solution. EMBO Rep 20(11):e47016 (2019)
...Liu ZY, Cheng ML, Ma J, Wang Y, Qin CF, Fang X

R_g^Guinier	3.9	nm
D_max	13.4	nm
Volume^Porod	67	nm³

SASDGJ3 – Xrn1 resistance RNA1 from West Nile virus

Xrn1 resistance RNA-1 from West Nile virus experimental SAS data

Sample:	Xrn1 resistance RNA-1 from West Nile virus monomer, 25 kDa West Nile virus RNA
Buffer:	20mM Tris-HCl, 100mM NaCl, 5mM MgCl2, pH: 7.5
Experiment:	SAXS data collected at 12-ID-B SAXS/WAXS, Advanced Photon Source (APS), Argonne National Laboratory on 2016 Dec 9

Long non-coding subgenomic flavivirus RNAs have extended 3D structures and are flexible in solution. EMBO Rep 20(11):e47016 (2019)
...Liu ZY, Cheng ML, Ma J, Wang Y, Qin CF, Fang X

R_g^Guinier	2.4	nm
D_max	8.4	nm
Volume^Porod	34	nm³

SASDGK3 – Xrn1 resistance RNA1 from Murray Valley Encephalitis

Xrn1 resistance RNA-1 from Murray Valley Encephalitis experimental SAS data

Sample:	Xrn1 resistance RNA-1 from Murray Valley Encephalitis monomer, 26 kDa Murray Valley Encephalitis RNA
Buffer:	20mM Tris-HCl, 100mM NaCl, 5mM MgCl2, pH: 7.5
Experiment:	SAXS data collected at 12-ID-B SAXS/WAXS, Advanced Photon Source (APS), Argonne National Laboratory on 2016 Dec 9

Long non-coding subgenomic flavivirus RNAs have extended 3D structures and are flexible in solution. EMBO Rep 20(11):e47016 (2019)
...Liu ZY, Cheng ML, Ma J, Wang Y, Qin CF, Fang X

R_g^Guinier	2.4	nm
D_max	8.8	nm
Volume^Porod	31	nm³

SASDKK3 – SEC-SAXS of Presequence Protease (PreP)

Presequence protease, mitochondrial experimental SAS data

Presequence protease, mitochondrial Kratky plot

Sample:	Presequence protease, mitochondrial monomer, 115 kDa Homo sapiens protein
Buffer:	20 mM Tris, 100 mM NaCl, pH: 7.7
Experiment:	SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2020 Mar 4

Structural basis for the mechanisms of human presequence protease conformational switch and substrate recognition Nature Communications 13(1) (2022)
...Liu C, Koehler C, Zhao M, Potter C, Carragher B, Li S, Tang W

R_g^Guinier	3.2	nm
D_max	9.1	nm
Volume^Porod	170	nm³

SASDBL3 – Highly similar to Actin cross-linking family protein 7 (ACF7) Homo Sapiens

cDNA FLJ45612 fis, clone BRTHA3025073, highly similar to Actin cross-linking family protein 7 experimental SAS data

cDNA FLJ45612 fis, clone BRTHA3025073, highly similar to Actin cross-linking family protein 7 Kratky plot

Sample:	cDNA FLJ45612 fis, clone BRTHA3025073, highly similar to Actin cross-linking family protein 7 monomer, 46 kDa Homo sapiens protein
Buffer:	PBS, pH: 7.4
Experiment:	SAXS data collected at 12-ID-B SAXS/WAXS, Advanced Photon Source (APS), Argonne National Laboratory on 2014 Nov 10

In vivo epidermal migration requires focal adhesion targeting of ACF7. Nat Commun 7:11692 (2016)
...Liu H, Lyu W, Tang WJ, Chen SY, Yang F, Liang H, Wu X

R_g^Guinier	3.4	nm
D_max	13.5	nm
Volume^Porod	53	nm³

SASDGL3 – 3'SL from Dengue virus 2

3'SL from Dengue virus 2 experimental SAS data

Sample:	3'SL from Dengue virus 2 monomer, 31 kDa Dengue virus 2 RNA
Buffer:	20mM Tris-HCl, 100mM NaCl, 5mM MgCl2, pH: 7.5
Experiment:	SAXS data collected at 12-ID-B SAXS/WAXS, Advanced Photon Source (APS), Argonne National Laboratory on 2017 Feb 24

Long non-coding subgenomic flavivirus RNAs have extended 3D structures and are flexible in solution. EMBO Rep 20(11):e47016 (2019)
...Liu ZY, Cheng ML, Ma J, Wang Y, Qin CF, Fang X

R_g^Guinier	3.6	nm
D_max	14.1	nm
Volume^Porod	40	nm³

SASDKL3 – SEC-SAXS of Presequence Protease (PreP) with inhibitor MitoBloCK-60 (MB-60)

Sample:	Presequence protease, mitochondrial monomer, 115 kDa Homo sapiens protein
Buffer:	20 mM Tris, 100 mM NaCl, pH: 7.7
Experiment:	SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2020 Mar 7

R_g^Guinier	3.1	nm
D_max	9.1	nm
Volume^Porod	165	nm³

SASDGM3 – Xrn1 resistance RNA1-2 from Dengue virus 2

Sample:	Xrn1 resistance RNA1-2 from Dengue virus 2 monomer, 46 kDa Dengue virus 2 RNA
Buffer:	20mM Tris-HCl, 100mM NaCl, 5mM MgCl2, pH: 7.5
Experiment:	SAXS data collected at 12-ID-B SAXS/WAXS, Advanced Photon Source (APS), Argonne National Laboratory on 2016 Dec 9

Long non-coding subgenomic flavivirus RNAs have extended 3D structures and are flexible in solution. EMBO Rep 20(11):e47016 (2019)
...Liu ZY, Cheng ML, Ma J, Wang Y, Qin CF, Fang X

R_g^Guinier	3.5	nm
D_max	12.5	nm
Volume^Porod	65	nm³

SASDKM3 – SEC-SAXS of Presequence Protease (PreP) with pre-sequence of citrate synthase (1-27)

Presequence protease, mitochondrialCitrate synthase, mitochondrial experimental SAS data

Presequence protease, mitochondrial Citrate synthase, mitochondrial Kratky plot

Sample:	Presequence protease, mitochondrial monomer, 115 kDa Homo sapiens protein Citrate synthase, mitochondrial monomer, 3 kDa Homo sapiens protein
Buffer:	20 mM Tris, 100 mM NaCl , 20 mM EDTA, pH: 7.7
Experiment:	SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2020 Nov 4

R_g^Guinier	3.1	nm
D_max	8.7	nm
Volume^Porod	165	nm³

SASDBN3 – Highly similar to Actin cross-linking family protein 7 (ACF7) Y259D mutant Homo Sapiens

cDNA FLJ45612 fis, clone BRTHA3025073, highly similar to Actin cross-linking family protein 7 Y259D mutant experimental SAS data

cDNA FLJ45612 fis, clone BRTHA3025073, highly similar to Actin cross-linking family protein 7 Y259D mutant Kratky plot

Sample:	cDNA FLJ45612 fis, clone BRTHA3025073, highly similar to Actin cross-linking family protein 7 Y259D mutant monomer, 46 kDa Homo sapiens protein
Buffer:	PBS, pH: 7.4
Experiment:	SAXS data collected at 12-ID-B SAXS/WAXS, Advanced Photon Source (APS), Argonne National Laboratory on 2014 Nov 7

In vivo epidermal migration requires focal adhesion targeting of ACF7. Nat Commun 7:11692 (2016)
...Liu H, Lyu W, Tang WJ, Chen SY, Yang F, Liang H, Wu X

R_g^Guinier	3.4	nm
D_max	13.5	nm
Volume^Porod	55	nm³

SASDGN3 – Xrn1 resistance RNA2 from Zika virus

Sample:	Xrn1 resistance RNA2 from Zika virus monomer, 22 kDa Zika virus RNA
Buffer:	20mM Tris-HCl, 100mM NaCl, 5mM MgCl2, pH: 7.5
Experiment:	SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2017 Sep 11

Long non-coding subgenomic flavivirus RNAs have extended 3D structures and are flexible in solution. EMBO Rep 20(11):e47016 (2019)
...Liu ZY, Cheng ML, Ma J, Wang Y, Qin CF, Fang X

R_g^Guinier	2.1	nm
D_max	7.2	nm
Volume^Porod	29	nm³

SASDKN3 – SEC-SAXS of Presequence Protease (PreP) with Amyloid beta precursor protein (1-40)

Presequence protease, mitochondrialAmyloid-beta precursor protein experimental SAS data

Presequence protease, mitochondrial Amyloid-beta precursor protein Kratky plot

Sample:	Presequence protease, mitochondrial monomer, 115 kDa Homo sapiens protein Amyloid-beta precursor protein monomer, 4 kDa Homo sapiens protein
Buffer:	20 mM Tris, 100 mM NaCl , 20 mM EDTA, pH: 7.7
Experiment:	SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2020 Mar 7

R_g^Guinier	3.0	nm
D_max	8.5	nm
Volume^Porod	175	nm³

SASDGP3 – Xrn1 resistance RNA1-2 from West Nile virus

Xrn1 resistance RNA1-2 from West Nile virus experimental SAS data

Sample:	Xrn1 resistance RNA1-2 from West Nile virus monomer, 75 kDa West Nile virus RNA
Buffer:	20mM Tris-HCl, 100mM NaCl, 5mM MgCl2, pH: 7.5
Experiment:	SAXS data collected at 12-ID-B SAXS/WAXS, Advanced Photon Source (APS), Argonne National Laboratory on 2017 Apr 2

Long non-coding subgenomic flavivirus RNAs have extended 3D structures and are flexible in solution. EMBO Rep 20(11):e47016 (2019)
...Liu ZY, Cheng ML, Ma J, Wang Y, Qin CF, Fang X

R_g^Guinier	4.7	nm
D_max	17.4	nm
Volume^Porod	235	nm³

SASDGQ3 – SL3 from West Nile virus

SL3 from West Nile virus experimental SAS data

Sample:	SL3 from West Nile virus monomer, 23 kDa West Nile virus RNA
Buffer:	20mM Tris-HCl, 100mM NaCl, 5mM MgCl2, pH: 7.5
Experiment:	SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2017 Jun 27

Long non-coding subgenomic flavivirus RNAs have extended 3D structures and are flexible in solution. EMBO Rep 20(11):e47016 (2019)
...Liu ZY, Cheng ML, Ma J, Wang Y, Qin CF, Fang X

R_g^Guinier	2.8	nm
D_max	9.5	nm
Volume^Porod	29	nm³

SASDGR3 – Xrn1 resistance RNA2 from Dengue virus 2

Xrn1 resistance RNA2 from Dengue virus 2 experimental SAS data

Sample:	Xrn1 resistance RNA2 from Dengue virus 2 monomer, 21 kDa Dengue virus 2 RNA
Buffer:	20mM Tris-HCl, 100mM NaCl, 5mM MgCl2, pH: 7.5
Experiment:	SAXS data collected at 12-ID-B SAXS/WAXS, Advanced Photon Source (APS), Argonne National Laboratory on 2017 Mar 16

Long non-coding subgenomic flavivirus RNAs have extended 3D structures and are flexible in solution. EMBO Rep 20(11):e47016 (2019)
...Liu ZY, Cheng ML, Ma J, Wang Y, Qin CF, Fang X

R_g^Guinier	2.2	nm
D_max	7.6	nm
Volume^Porod	29	nm³

SASDGS3 – DB12 from Dengue virus 2

DB12 from Dengue virus 2 experimental SAS data

Sample:	DB12 from Dengue virus 2 monomer, 56 kDa Dengue virus 2 RNA
Buffer:	20mM Tris-HCl, 100mM NaCl, 5mM MgCl2, pH: 7.5
Experiment:	SAXS data collected at 12-ID-B SAXS/WAXS, Advanced Photon Source (APS), Argonne National Laboratory on 2017 Feb 24

Long non-coding subgenomic flavivirus RNAs have extended 3D structures and are flexible in solution. EMBO Rep 20(11):e47016 (2019)
...Liu ZY, Cheng ML, Ma J, Wang Y, Qin CF, Fang X

R_g^Guinier	4.7	nm
D_max	16.2	nm
Volume^Porod	96	nm³

SASDUS3 – Dark-adapted photocobilin diguanylate cyclase fusion from Acidimicrobiaceae bacterium

GGDEF domain-containing protein experimental SAS data

Sample:	GGDEF domain-containing protein dimer, 132 kDa Acidimicrobiaceae bacterium protein
Buffer:	20 mM HEPES, 150 mM NaCl, pH: 6.8
Experiment:	SAXS data collected at BM29, ESRF on 2022 Jan 21

Photocobilins integrate B(12) and bilin photochemistry for enzyme control. Nat Commun 15(1):2740 (2024)
...Liu C, Patel K, Johannissen LO, Zhu L, Cliff MJ, Yan C, Schirò G, Weik M, Sakuma M, Levy CW, Leys D, Heyes DJ, Scrutton NS

R_g^Guinier	4.1	nm
D_max	14.9	nm
Volume^Porod	194	nm³

SASDGT3 – Xrn1 resistance RNA2 from West Nile virus

Xrn1 resistance RNA2 from West Nile virus experimental SAS data

Sample:	Xrn1 resistance RNA2 from West Nile virus monomer, 23 kDa West Nile virus RNA
Buffer:	20mM Tris-HCl, 100mM NaCl, 5mM MgCl2, pH: 7.5
Experiment:	SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2017 Apr 7

Long non-coding subgenomic flavivirus RNAs have extended 3D structures and are flexible in solution. EMBO Rep 20(11):e47016 (2019)
...Liu ZY, Cheng ML, Ma J, Wang Y, Qin CF, Fang X

R_g^Guinier	2.2	nm
D_max	7.7	nm
Volume^Porod	30	nm³

SASDUT3 – Light-adapted photocobilin diguanylate cyclase fusion from Acidimicrobiaceae bacterium

Sample:	GGDEF domain-containing protein dimer, 132 kDa Acidimicrobiaceae bacterium protein
Buffer:	20 mM HEPES, 150 mM NaCl, pH: 6.8
Experiment:	SAXS data collected at BM29, ESRF on 2022 Jan 21

R_g^Guinier	5.0	nm
D_max	18.5	nm
Volume^Porod	170	nm³

SASDGU3 – Xrn1 resistance RNA2 from Murray Valley Encephalitis

Xrn1 resistance RNA2 from Murray Valley Encephalitis experimental SAS data

Sample:	Xrn1 resistance RNA2 from Murray Valley Encephalitis monomer, 22 kDa Murray Valley Encephalitis RNA
Buffer:	20mM Tris-HCl, 100mM NaCl, 5mM MgCl2, pH: 7.5
Experiment:	SAXS data collected at 12-ID-B SAXS/WAXS, Advanced Photon Source (APS), Argonne National Laboratory on 2016 Dec 14

Long non-coding subgenomic flavivirus RNAs have extended 3D structures and are flexible in solution. EMBO Rep 20(11):e47016 (2019)
...Liu ZY, Cheng ML, Ma J, Wang Y, Qin CF, Fang X

R_g^Guinier	2.2	nm
D_max	8.2	nm
Volume^Porod	28	nm³

SASDMU3 – Overall conformation and interdomain arrangement of Vibrio collagenase VhaC in solution.

Vibrio collagenase VhaC experimental SAS data

Sample:	Vibrio collagenase VhaC monomer, 90 kDa Vibrio harveyi protein
Buffer:	10 mM Tris-HCl, 100 mM NaCl, pH: 8
Experiment:	SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2021 Jan 1

Structure of Vibrio collagenase VhaC provides insight into the mechanism of bacterial collagenolysis. Nat Commun 13(1):566 (2022)
...Liu SC, Liu G, Zhang X, Li CY, Peng M, Li F, Li S, Chen Y, Chen XL, Zhang YZ

R_g^Guinier	4.3	nm
D_max	17.6	nm
Volume^Porod	148	nm³

SASDGV3 – DB12 from Zika virus

DB12 from Zika virus experimental SAS data

Sample:	DB12 from Zika virus monomer, 47 kDa Zika virus RNA
Buffer:	20mM Tris-HCl, 100mM NaCl, 5mM MgCl2, pH: 7.5
Experiment:	SAXS data collected at 12-ID-B SAXS/WAXS, Advanced Photon Source (APS), Argonne National Laboratory on 2017 Apr 2

Long non-coding subgenomic flavivirus RNAs have extended 3D structures and are flexible in solution. EMBO Rep 20(11):e47016 (2019)
...Liu ZY, Cheng ML, Ma J, Wang Y, Qin CF, Fang X

R_g^Guinier	3.3	nm
D_max	11.2	nm
Volume^Porod	92	nm³

SASDGW3 – DB12 from West Nile virus

DB12 from West Nile virus experimental SAS data

Sample:	DB12 from West Nile virus monomer, 59 kDa West Nile virus RNA
Buffer:	20mM Tris-HCl, 100mM NaCl, 5mM MgCl2, pH: 7.5
Experiment:	SAXS data collected at 12-ID-B SAXS/WAXS, Advanced Photon Source (APS), Argonne National Laboratory on 2017 Jan 19

Long non-coding subgenomic flavivirus RNAs have extended 3D structures and are flexible in solution. EMBO Rep 20(11):e47016 (2019)
...Liu ZY, Cheng ML, Ma J, Wang Y, Qin CF, Fang X

R_g^Guinier	3.9	nm
D_max	13.4	nm
Volume^Porod	160	nm³

SASDGX3 – 3'SL from Zika virus

3'SL from Zika virus experimental SAS data

Sample:	3'SL from Zika virus monomer, 32 kDa Zika virus RNA
Buffer:	20mM Tris-HCl, 100mM NaCl, 5mM MgCl2, pH: 7.5
Experiment:	SAXS data collected at 12-ID-B SAXS/WAXS, Advanced Photon Source (APS), Argonne National Laboratory on 2016 Dec 9

Long non-coding subgenomic flavivirus RNAs have extended 3D structures and are flexible in solution. EMBO Rep 20(11):e47016 (2019)
...Liu ZY, Cheng ML, Ma J, Wang Y, Qin CF, Fang X

R_g^Guinier	3.9	nm
D_max	14.1	nm
Volume^Porod	52	nm³

SASDGY3 – 3'SL from West Nile virus

3'SL from West Nile virus experimental SAS data

Sample:	3'SL from West Nile virus monomer, 31 kDa West Nile virus RNA
Buffer:	20mM Tris-HCl, 100mM NaCl, 5mM MgCl2, pH: 7.5
Experiment:	SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2017 Apr 7

Long non-coding subgenomic flavivirus RNAs have extended 3D structures and are flexible in solution. EMBO Rep 20(11):e47016 (2019)
...Liu ZY, Cheng ML, Ma J, Wang Y, Qin CF, Fang X

R_g^Guinier	3.5	nm
D_max	13.2	nm
Volume^Porod	39	nm³

SASDGZ3 – Subgenomic flavivirus RNAs from Zika virus

Subgenomic flavivirus RNA from Zika virus experimental SAS data

Subgenomic flavivirus RNAs from Zika virus Rg histogram

Sample:	Subgenomic flavivirus RNA from Zika virus monomer, 133 kDa Zika virus RNA
Buffer:	20mM Tris-HCl, 100mM NaCl, 5mM MgCl2, pH: 7.5
Experiment:	SAXS data collected at 12-ID-B SAXS/WAXS, Advanced Photon Source (APS), Argonne National Laboratory on 2017 Mar 13

Long non-coding subgenomic flavivirus RNAs have extended 3D structures and are flexible in solution. EMBO Rep 20(11):e47016 (2019)
...Liu ZY, Cheng ML, Ma J, Wang Y, Qin CF, Fang X

R_g^Guinier	7.5	nm
D_max	29.6	nm
Volume^Porod	230	nm³

SASDG24 – Subgenomic flavivirus RNAs from Dengue virus 2

Subgenomic flavivirus RNAs from Dengue virus 2 experimental SAS data

Subgenomic flavivirus RNAs from Dengue virus 2 Rg histogram

Sample:	Subgenomic flavivirus RNAs from Dengue virus 2 monomer, 137 kDa Dengue virus 2 RNA
Buffer:	20mM Tris-HCl, 100mM NaCl, 5mM MgCl2, pH: 7.5
Experiment:	SAXS data collected at 12-ID-B SAXS/WAXS, Advanced Photon Source (APS), Argonne National Laboratory on 2016 Dec 16

Long non-coding subgenomic flavivirus RNAs have extended 3D structures and are flexible in solution. EMBO Rep 20(11):e47016 (2019)
...Liu ZY, Cheng ML, Ma J, Wang Y, Qin CF, Fang X

R_g^Guinier	7.9	nm
D_max	30.5	nm
Volume^Porod	236	nm³

SASDG34 – Subgenomic flavivirus RNAs from West nile virus

Subgenomic flavivirus RNAs from West nile virus experimental SAS data

Subgenomic flavivirus RNAs from West nile virus Rg histogram

Sample:	Subgenomic flavivirus RNAs from West nile virus monomer, 170 kDa West Nile virus RNA
Buffer:	20mM Tris-HCl, 100mM NaCl, 5mM MgCl2, pH: 7.5
Experiment:	SAXS data collected at 12-ID-B SAXS/WAXS, Advanced Photon Source (APS), Argonne National Laboratory on 2017 Mar 13

Long non-coding subgenomic flavivirus RNAs have extended 3D structures and are flexible in solution. EMBO Rep 20(11):e47016 (2019)
...Liu ZY, Cheng ML, Ma J, Wang Y, Qin CF, Fang X

R_g^Guinier	7.9	nm
D_max	31.8	nm
Volume^Porod	261	nm³

SASDD65 – Ubiquitinating/deubiquitinating enzyme SdeA 207 914

Ubiquitinating/deubiquitinating enzyme SdeA experimental SAS data

Sample:	Ubiquitinating/deubiquitinating enzyme SdeA monomer, 72 kDa Legionella pneumophila subsp. … protein
Buffer:	10 mM HEPES 150 mM NaCl 1 mM TCEP, pH: 7.5
Experiment:	SAXS data collected at EMBL P12, PETRA III on 2017 Nov 26

Insights into catalysis and function of phosphoribosyl-linked serine ubiquitination. Nature 557(7707):734-738 (2018)
...Liu Y, Gan N, Basquin J, Grumati P, Luo ZQ, Dikic I

R_g^Guinier	3.5	nm
D_max	11.2	nm
Volume^Porod	128	nm³

SASDF85 – Pseudomonas aeruginosa antitoxin HigA: apo PaHigA

Uncharacterized protein experimental SAS data

Sample:	Uncharacterized protein dimer, 22 kDa Pseudomonas aeruginosa protein
Buffer:	20 mM Tris, 300 mM NaCl, 5% (v/v) glycerol, and 1 mM PMSF, pH: 8
Experiment:	SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2018 Dec 21

Structural Insights Into the Transcriptional Regulation of HigBA Toxin–Antitoxin System by Antitoxin HigA in Pseudomonas aeruginosa Frontiers in Microbiology 10 (2020)
Liu Y, Gao Z, Liu G, Geng Z, Dong Y, Zhang H

R_g^Guinier	2.0	nm
D_max	6.6	nm
Volume^Porod	23	nm³

SASDD95 – Neurexin 1a L5L6

Sample:	Neurexin 1a L5L6 monomer, 44 kDa protein
Buffer:	20 mM HEPES pH 8, 150 mM NaCl, 0.5mM CaCl2, pH: 8
Experiment:	SAXS data collected at Rigaku BioSAXS-1000, Sealy Center For Structural Biology, UTMB-G on 2016 Sep 6

Structural Plasticity of Neurexin 1α: Implications for its Role as Synaptic Organizer. J Mol Biol 430(21):4325-4343 (2018)
Liu J, Misra A, Reddy MVVVS, White MA, Ren G, Rudenko G

R_g^Guinier	3.0	nm
D_max	10.0	nm
Volume^Porod	69	nm³

SASDF95 – Pseudomonas aeruginosa antitoxin HigA bound to duplex DNA: PaHigA-DNA complex

Uncharacterized proteinDNA Duplex experimental SAS data

Sample:	Uncharacterized protein dimer, 22 kDa Pseudomonas aeruginosa protein DNA Duplex dimer, 20 kDa DNA
Buffer:	20 mM Tris, 300 mM NaCl, 5% (v/v) glycerol, and 1 mM PMSF, pH: 8
Experiment:	SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2018 Sep 19

R_g^Guinier	2.9	nm
D_max	9.8	nm
Volume^Porod	81	nm³

SASDDA5 – Neurexin 1a L5L6 with ss6 insert

Neurexin 1a L5L6 with ss6 insert experimental SAS data

Neurexin 1a L5L6 with ss6 insert Rg histogram

Sample:	Neurexin 1a L5L6 with ss6 insert monomer, 45 kDa Homo sapiens protein
Buffer:	20 mM HEPES pH 8, 150 mM NaCl, 0.5mM CaCl2, pH: 8
Experiment:	SAXS data collected at Rigaku BioSAXS-1000, Sealy Center For Structural Biology, UTMB-G on 2016 Sep 26

Structural Plasticity of Neurexin 1α: Implications for its Role as Synaptic Organizer. J Mol Biol 430(21):4325-4343 (2018)
Liu J, Misra A, Reddy MVVVS, White MA, Ren G, Rudenko G

R_g^Guinier	3.2	nm
D_max	12.4	nm
Volume^Porod	70	nm³

SASDPB5 – ...Liu buffer)

Xist A-repeat lncRNA experimental SAS data

Sample:	Xist A-repeat lncRNA monomer, 148 kDa Homo sapiens RNA
Buffer:	25 mM K-HEPES, 0.1 mM Na-EDTA, 150 mM KCl, 15 mM MgCl2, pH: 7
Experiment:	SAXS data collected at EMBL P12, PETRA III on 2020 Jun 20

Cotranscriptional folding of the lncRNA Xist A-repeats indicates a modular structure
Alisha Jones

R_g^Guinier	12.1	nm
D_max	45.0	nm

SASDFM5 – Mutant 2-amino-3-carboxymuconate 6-semialdehyde decarboxylase, H110A tetramer, at pH 8.5

2-amino-3-carboxymuconate 6-semialdehyde decarboxylase experimental SAS data

Sample:	2-amino-3-carboxymuconate 6-semialdehyde decarboxylase tetramer, 159 kDa Pseudomonas fluorescens protein
Buffer:	50 mM Tris, 5 mM DTT, pH: 8.5
Experiment:	SAXS data collected at BL4-2, Stanford Synchrotron Radiation Lightsource (SSRL) on 2018 Jul 15

Quaternary structure of α-amino-β-carboxymuconate-ϵ-semialdehyde decarboxylase (ACMSD) controls its activity. J Biol Chem 294(30):11609-11621 (2019)
...Liu A

R_g^Guinier	5.2	nm
D_max	19.0	nm
Volume^Porod	238	nm³

SASDFN5 – Wild type 2-amino-3-carboxymuconate 6-semialdehyde decarboxylase, ACMSD tetramer, at pH 7.0

Sample:	2-amino-3-carboxymuconate 6-semialdehyde decarboxylase tetramer, 159 kDa Pseudomonas fluorescens protein
Buffer:	25 mM HEPES, 5 mM DTT, pH: 7
Experiment:	SAXS data collected at BL4-2, Stanford Synchrotron Radiation Lightsource (SSRL) on 2018 Jan 10

Quaternary structure of α-amino-β-carboxymuconate-ϵ-semialdehyde decarboxylase (ACMSD) controls its activity. J Biol Chem 294(30):11609-11621 (2019)
...Liu A

R_g^Guinier	4.7	nm
D_max	17.5	nm
Volume^Porod	195	nm³

SASDMR5 – Tn3 family transposase (TnpA WT)

Sample:	TnpA transposase dimer, 234 kDa Bacillus thuringiensis serovar … protein
Buffer:	50 mM HEPES, 200 mM NaCl, 100 mM L-Arg HCL, pH: 7.9
Experiment:	SAXS data collected at SWING, SOLEIL on 2017 Nov 2

AFM-based force spectroscopy unravels stepwise formation of the DNA transposition complex in the widespread Tn3 family mobile genetic elements. Nucleic Acids Res (2023)
...Liu Y, Stulemeijer C, Derclaye S, Efremov RG, Hallet B, Alsteens D

R_g^Guinier	4.6	nm
D_max	16.0	nm
Volume^Porod	480	nm³

SASDRR5 – Like Early Starvation 1

Sample:	At3g55760 monomer, 60 kDa Arabidopsis thaliana protein
Buffer:	50 mM Tris, 150 mM NaCl, 10% glycerol, 2 mM DTT, pH: 8
Experiment:	SAXS data collected at SWING, SOLEIL on 2016 Dec 8

LIKE EARLY STARVATION 1 and EARLY STARVATION 1 promote and stabilize amylopectin phase transition in starch biosynthesis. Sci Adv 9(21):eadg7448 (2023)
Liu C, Pfister B, Osman R, Ritter M, Heutinck A, Sharma M, Eicke S, Fischer-Stettler M, Seung D, Bompard C, Abt MR, Zeeman SC

R_g^Guinier	3.7	nm
D_max	16.0	nm
Volume^Porod	121	nm³

SASDRS5 – Early Starvation 1 from Arabidopsis thaliana

Inactive purple acid phosphatase-like protein experimental SAS data

Inactive purple acid phosphatase-like protein Kratky plot

Sample:	Inactive purple acid phosphatase-like protein monomer, 40 kDa Arabidopsis thaliana protein
Buffer:	50 mM Tris, 150 mM NaCl, 10% glycerol, 2 mM DTT, pH: 8
Experiment:	SAXS data collected at SWING, SOLEIL on 2016 Dec 8

R_g^Guinier	3.2	nm
D_max	11.5	nm
Volume^Porod	83	nm³

SASDP56 – SARS-CoV-2 non-structural protein 8 (nsp8, dimer) in 250 mM NaCl buffer

Replicase polyprotein 1a (Non-structural protein 8, SARS-CoV-2) experimental SAS data

Replicase polyprotein 1a (Non-structural protein 8, SARS-CoV-2) Kratky plot

Sample:	Replicase polyprotein 1a (Non-structural protein 8, SARS-CoV-2) dimer, 44 kDa Severe acute respiratory … protein
Buffer:	20 mM HEPES pH 7.4, 250 mM NaCl, pH: 7.4
Experiment:	SANS data collected at BL01-Small Angle Neutron Scattering, China Spallation Neutron Source on 2021 Jul 19

Multiscale characterization reveals oligomerization dependent phase separation of primer-independent RNA polymerase nsp8 from SARS-CoV-2. Commun Biol 5(1):925 (2022)
...Liu J

R_g^Guinier

4.1

SASDP66 – SARS-CoV-2 non-structural protein 8 (nsp8, dimer) in 500 mM NaCl buffer

Sample:	Replicase polyprotein 1a (Non-structural protein 8, SARS-CoV-2) dimer, 44 kDa Severe acute respiratory … protein
Buffer:	20 mM HEPES pH 7.4, 500 mM NaCl, pH: 7.4
Experiment:	SANS data collected at BL01-Small Angle Neutron Scattering, China Spallation Neutron Source on 2021 Jul 19

Multiscale characterization reveals oligomerization dependent phase separation of primer-independent RNA polymerase nsp8 from SARS-CoV-2. Commun Biol 5(1):925 (2022)
...Liu J

R_g^Guinier	3.8	nm
D_max	14.0	nm
Volume^Porod	98	nm³

SASDP76 – SARS-CoV-2 non-structural protein 8 (nsp8, dimer) in 1000 mM NaCl buffer

Sample:	Replicase polyprotein 1a (Non-structural protein 8, SARS-CoV-2) dimer, 44 kDa Severe acute respiratory … protein
Buffer:	20 mM HEPES pH 7.4, 1000 mM NaCl, pH: 7.4
Experiment:	SANS data collected at BL01-Small Angle Neutron Scattering, China Spallation Neutron Source on 2021 Jul 19

Multiscale characterization reveals oligomerization dependent phase separation of primer-independent RNA polymerase nsp8 from SARS-CoV-2. Commun Biol 5(1):925 (2022)
...Liu J

R_g^Guinier	3.8	nm
D_max	14.0	nm
Volume^Porod	100	nm³

SASDP86 – SARS-CoV-2 non-structural protein 8 (nsp8, tetramer) in 250 mM NaCl buffer

Sample:	Replicase polyprotein 1a (Non-structural protein 8, SARS-CoV-2) tetramer, 88 kDa Severe acute respiratory … protein
Buffer:	20 mM HEPES pH 7.4, 250 mM NaCl, pH: 7.4
Experiment:	SANS data collected at BL01-Small Angle Neutron Scattering, China Spallation Neutron Source on 2021 Jul 19

Multiscale characterization reveals oligomerization dependent phase separation of primer-independent RNA polymerase nsp8 from SARS-CoV-2. Commun Biol 5(1):925 (2022)
...Liu J

R_g^Guinier	6.3	nm
D_max	24.0	nm

SASDP96 – SARS-CoV-2 non-structural protein 8 (nsp8, tetramer) in 500 mM NaCl buffer

Sample:	Replicase polyprotein 1a (Non-structural protein 8, SARS-CoV-2) tetramer, 88 kDa Severe acute respiratory … protein
Buffer:	20 mM HEPES pH 7.4, 500 mM NaCl, pH: 7.4
Experiment:	SANS data collected at BL01-Small Angle Neutron Scattering, China Spallation Neutron Source on 2021 Jul 19

Multiscale characterization reveals oligomerization dependent phase separation of primer-independent RNA polymerase nsp8 from SARS-CoV-2. Commun Biol 5(1):925 (2022)
...Liu J

R_g^Guinier	5.2	nm
D_max	18.0	nm

SASDPA6 – SARS-CoV-2 non-structural protein 8 (nsp8, tetramer) in 1000 mM NaCl buffer

Sample:	Replicase polyprotein 1a (Non-structural protein 8, SARS-CoV-2) tetramer, 88 kDa Severe acute respiratory … protein
Buffer:	20 mM HEPES pH 7.4, 1000 mM NaCl, pH: 7.4
Experiment:	SANS data collected at BL01-Small Angle Neutron Scattering, China Spallation Neutron Source on 2021 Jul 19

Multiscale characterization reveals oligomerization dependent phase separation of primer-independent RNA polymerase nsp8 from SARS-CoV-2. Commun Biol 5(1):925 (2022)
...Liu J

R_g^Guinier	4.8	nm
D_max	16.0	nm

SASDAH6 – WbdD(1-459)

bifunctional kinase- methyltransferase WbdD experimental SAS data

Sample:	bifunctional kinase- methyltransferase WbdD monomer, 59 kDa Escherichia coli protein
Buffer:	20 mM BisTris 50 mM NaCl 5 mM DTT, pH: 7
Experiment:	SAXS data collected at EMBL X33, DORIS III, DESY on 2011 Sep 23

A coiled-coil domain acts as a molecular ruler to regulate O-antigen chain length in lipopolysaccharide. Nat Struct Mol Biol 22(1):50-56 (2015)
...Liu H, Whitfield C, Naismith JH

R_g^Guinier	3.1	nm
D_max	10.0	nm
Volume^Porod	90	nm³

SASDAJ6 – WbdD(1-556)

Sample:	bifunctional kinase- methyltransferase WbdD trimer, 190 kDa protein
Buffer:	20 mM BisTris 50 mM NaCl 5 mM DTT, pH: 7
Experiment:	SAXS data collected at EMBL X33, DORIS III, DESY on 2011 Dec 2

A coiled-coil domain acts as a molecular ruler to regulate O-antigen chain length in lipopolysaccharide. Nat Struct Mol Biol 22(1):50-56 (2015)
...Liu H, Whitfield C, Naismith JH

R_g^Guinier	5.2	nm
D_max	17.0	nm
Volume^Porod	380	nm³

SASDCL6 – Lys63-linked dimer ubiquitin

Sample:	Polyubiquitin-C dimer, 17 kDa Homo sapiens protein
Buffer:	100mM NaCl, 10mM sodium acetate, pH: 6
Experiment:	SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2016 Mar 24

Lys63-linked ubiquitin chain adopts multiple conformational states for specific target recognition. Elife 4 (2015)
Liu Z, Gong Z, Jiang WX, Yang J, Zhu WK, Guo DC, Zhang WP, Liu ML, Tang C

R_g^Guinier	2.1	nm
D_max	6.5	nm
Volume^Porod	24	nm³

SASDMQ6 – The N-terminus of E3 ubiquitin-protein ligase DTX3L (M1-Q200)

E3 ubiquitin-protein ligase DTX3L experimental SAS data

E3 ubiquitin-protein ligase DTX3L Kratky plot

Sample:	E3 ubiquitin-protein ligase DTX3L pentamer, 114 kDa Homo sapiens protein
Buffer:	30 mM HEPES, 350 mM NaCl, 10% glycerol, 0.5 mM TCEP, pH: 7.5
Experiment:	SAXS data collected at B21, Diamond Light Source on 2019 Feb 6

Reconstitution of the DTX3L-PARP9 complex reveals determinants for high affinity heterodimerization and multimeric assembly. Biochem J (2022)
...Liu F, Paschal BM, Lehtiö L

R_g^Guinier	4.7	nm
D_max	17.0	nm
Volume^Porod	200	nm³

SASDKX6 – PSK, an antimicrobial peptide from Chrysomya megacephala

PSK, an antimicrobial peptide from Chrysomya megacephala experimental SAS data

Sample:	PSK, an antimicrobial peptide from Chrysomya megacephala monomer, 10 kDa Chrysomya megacephala protein
Buffer:	20 mM Tris, 150 mM NaCl, 1 mM DTT, pH: 8
Experiment:	SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2018 Dec 7

Crystal and solution structures of a novel antimicrobial peptide from Chrysomya megacephala. Acta Crystallogr D Struct Biol 77(Pt 7):894-903 (2021)
...Liu W

R_g^Guinier	1.6	nm
D_max	5.0	nm
Volume^Porod	18	nm³

SASDBZ6 – Draxin

Sample:	Draxin monomer, 45 kDa Homo sapiens protein
Buffer:	20 mM HEPES 150 mM NaCl, pH: 7.5
Experiment:	SAXS data collected at EMBL P12, PETRA III on 2015 Aug 19

Structural Basis for Draxin-Modulated Axon Guidance and Fasciculation by Netrin-1 through DCC. Neuron 97(6):1261-1267.e4 (2018)
Liu Y, Bhowmick T, Liu Y, Gao X, Mertens HDT, Svergun DI, Xiao J, Zhang Y, Wang JH, Meijers R

R_g^Guinier	4.2	nm
D_max	15.0	nm
Volume^Porod	87	nm³

SASDE47 – Aldehyde dehydrogenase 16 from Loktanella sp. (LsALDH16): 2 mg/ml

Aldehyde dehydrogenase 16 from Loktanella sp. experimental SAS data

Sample:	Aldehyde dehydrogenase 16 from Loktanella sp. dimer, 161 kDa Loktanella sp. 3ANDIMAR09 protein
Buffer:	20 mM Tris-HCl, 100 mM NaCl, 2.0% glycerol, 0.5 mM Tris(3-hydroxypropyl)phosphine, pH: 8
Experiment:	SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2017 Dec 13

Crystal Structure of Aldehyde Dehydrogenase 16 Reveals Trans-Hierarchical Structural Similarity and a New Dimer. J Mol Biol (2018)
Liu LK, Tanner JJ

R_g^Guinier	3.6	nm
D_max	10.9	nm
Volume^Porod	202	nm³

SASDE57 – Aldehyde dehydrogenase 16 from Loktanella sp. (LsALDH16): 4 mg/ml

Sample:	Aldehyde dehydrogenase 16 from Loktanella sp. dimer, 161 kDa Loktanella sp. 3ANDIMAR09 protein
Buffer:	20 mM Tris-HCl, 100 mM NaCl, 2.0% glycerol, 0.5 mM Tris(3-hydroxypropyl)phosphine, pH: 8
Experiment:	SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2017 Dec 13

Crystal Structure of Aldehyde Dehydrogenase 16 Reveals Trans-Hierarchical Structural Similarity and a New Dimer. J Mol Biol (2018)
Liu LK, Tanner JJ

R_g^Guinier	3.6	nm
D_max	11.2	nm
Volume^Porod	204	nm³

SASDE67 – Aldehyde dehydrogenase 16 from Loktanella sp. (LsALDH16): 6 mg/ml

Sample:	Aldehyde dehydrogenase 16 from Loktanella sp. dimer, 161 kDa Loktanella sp. 3ANDIMAR09 protein
Buffer:	20 mM Tris-HCl, 100 mM NaCl, 2.0% glycerol, 0.5 mM Tris(3-hydroxypropyl)phosphine, pH: 8
Experiment:	SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2017 Dec 13

Crystal Structure of Aldehyde Dehydrogenase 16 Reveals Trans-Hierarchical Structural Similarity and a New Dimer. J Mol Biol (2018)
Liu LK, Tanner JJ

R_g^Guinier	3.5	nm
D_max	10.6	nm
Volume^Porod	207	nm³

SASDS67 – Complex of BCL-6 corepressor linker-PUFD bound to Polycomb group RING finger protein 1 RAWUL, Lysine-specific demethylase 2B F-box-LRRs, and S-phase kinase-associated protein 1

BCL-6 corepressorLysine-specific demethylase 2BPolycomb group RING finger protein 1S-phase kinase-associated protein 1 experimental SAS data

Sample:	BCL-6 corepressor monomer, 16 kDa Homo sapiens protein Lysine-specific demethylase 2B monomer, 32 kDa Homo sapiens protein Polycomb group RING finger protein 1 monomer, 13 kDa Homo sapiens protein S-phase kinase-associated protein 1 monomer, 19 kDa Homo sapiens protein
Buffer:	20 mM Tris-HCl, 150 mM NaCl, pH: 7.5
Experiment:	SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2022 Sep 1

Calcium modulates the tethering of BCOR-PRC1.1 enzymatic core to KDM2B via liquid-liquid phase separation. Commun Biol 7(1):1112 (2024)
...Liu J, Xu J

R_g^Guinier	3.3	nm
D_max	11.5	nm
Volume^Porod	118	nm³

SASDE77 – Aldehyde dehydrogenase 16 from Loktanella sp. (LsALDH16): 8 mg/ml

Sample:	Aldehyde dehydrogenase 16 from Loktanella sp. dimer, 161 kDa Loktanella sp. 3ANDIMAR09 protein
Buffer:	20 mM Tris-HCl, 100 mM NaCl, 2.0% glycerol, 0.5 mM Tris(3-hydroxypropyl)phosphine, pH: 8
Experiment:	SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2017 Dec 13

Crystal Structure of Aldehyde Dehydrogenase 16 Reveals Trans-Hierarchical Structural Similarity and a New Dimer. J Mol Biol (2018)
Liu LK, Tanner JJ

R_g^Guinier	3.6	nm
D_max	10.8	nm
Volume^Porod	205	nm³

SASDS77 – Complex of BCL-6 corepressor ANK-linker-PUFD bound to Polycomb group RING finger protein 1 RAWUL, Lysine-specific demethylase 2B F-box-LRRs, and S-phase kinase-associated protein 1

Lysine-specific demethylase 2BPolycomb group RING finger protein 1S-phase kinase-associated protein 1BCL-6 corepressor experimental SAS data

Sample:	Lysine-specific demethylase 2B monomer, 32 kDa Homo sapiens protein Polycomb group RING finger protein 1 monomer, 13 kDa Homo sapiens protein S-phase kinase-associated protein 1 monomer, 19 kDa Homo sapiens protein BCL-6 corepressor monomer, 32 kDa Homo sapiens protein
Buffer:	20 mM Tris-HCl, 150 mM NaCl, pH: 7.5
Experiment:	SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2021 Jul 16

Calcium modulates the tethering of BCOR-PRC1.1 enzymatic core to KDM2B via liquid-liquid phase separation. Commun Biol 7(1):1112 (2024)
...Liu J, Xu J

R_g^Guinier	3.9	nm
D_max	16.5	nm
Volume^Porod	190	nm³

SASDE87 – Aldehyde dehydrogenase family 16 member A1 from Homo sapiens (HsALDH16A1): 1 mg/ml

Aldehyde dehydrogenase family 16 member A1 from Homo sapiens experimental SAS data

Sample:	Aldehyde dehydrogenase family 16 member A1 from Homo sapiens dimer, 171 kDa Homo sapiens protein
Buffer:	20 mM Tris-HCl, 100 mM NaCl, 2.0% glycerol, 0.5 mM Tris(3-hydroxypropyl)phosphine, pH: 8
Experiment:	SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2017 Dec 13

Crystal Structure of Aldehyde Dehydrogenase 16 Reveals Trans-Hierarchical Structural Similarity and a New Dimer. J Mol Biol (2018)
Liu LK, Tanner JJ

R_g^Guinier	3.6	nm
D_max	10.9	nm
Volume^Porod	230	nm³

SASDE97 – Aldehyde dehydrogenase family 16 member A1 from Homo sapiens (HsALDH16A1): 1.6 mg/ml

Sample:	Aldehyde dehydrogenase family 16 member A1 from Homo sapiens dimer, 171 kDa Homo sapiens protein
Buffer:	20 mM Tris-HCl, 100 mM NaCl, 2.0% glycerol, 0.5 mM Tris(3-hydroxypropyl)phosphine, pH: 8
Experiment:	SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2017 Dec 13

Crystal Structure of Aldehyde Dehydrogenase 16 Reveals Trans-Hierarchical Structural Similarity and a New Dimer. J Mol Biol (2018)
Liu LK, Tanner JJ

R_g^Guinier	3.8	nm
D_max	11.2	nm
Volume^Porod	236	nm³

SASDEA7 – Aldehyde dehydrogenase family 16 member A1 from Homo sapiens (HsALDH16A1): 3.2 mg/ml

Sample:	Aldehyde dehydrogenase family 16 member A1 from Homo sapiens dimer, 171 kDa Homo sapiens protein
Buffer:	20 mM Tris-HCl, 100 mM NaCl, 2.0% glycerol, 0.5 mM Tris(3-hydroxypropyl)phosphine, pH: 8
Experiment:	SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2017 Dec 13

Crystal Structure of Aldehyde Dehydrogenase 16 Reveals Trans-Hierarchical Structural Similarity and a New Dimer. J Mol Biol (2018)
Liu LK, Tanner JJ

R_g^Guinier	3.8	nm
D_max	11.5	nm
Volume^Porod	237	nm³

SASDCG7 – Lys63-linked diubiquitin at pH7.4

Sample:	Polyubiquitin-C dimer, 17 kDa Homo sapiens protein
Buffer:	20mM HEPES, 150mM NaCl, pH: 7.4
Experiment:	SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2016 Mar 24

Characterizing Protein Dynamics with Integrative Use of Bulk and Single-Molecule Techniques. Biochemistry 57(3):305-313 (2018)
Liu Z, Gong Z, Cao Y, Ding YH, Dong MQ, Lu YB, Zhang WP, Tang C

R_g^Guinier	2.0	nm
D_max	7.0	nm
Volume^Porod	22	nm³

SASDNJ7 – Non-pre-microRNA stem loop 2 (NPSL2)

Non-pre-microRNA stem loop 2 experimental SAS data

Sample:	Non-pre-microRNA stem loop 2 monomer, 14 kDa Homo sapiens RNA
Buffer:	50 mM potassium phosphate buffer, 1 mM MgCl2, 50 mM NaCl, pH: 7.5
Experiment:	SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2022 Feb 20

Solution structure of NPSL2, a regulatory element in the oncomiR-1 RNA. J Mol Biol :167688 (2022)
Liu Y, Munsayac A, Hall I, Keane SC

R_g^Guinier	2.0	nm
D_max	7.7	nm
Volume^Porod	15	nm³

SASDFS7 – Talin-1 head amino acids 1-405(Δ139-168)

Talin-1 (Δ139-168), human experimental SAS data

Talin-1 head amino acids 1-405(Δ139-168) Rg histogram

Sample:	Talin-1 (Δ139-168), human monomer, 48 kDa Homo sapiens protein
Buffer:	50 mM sodium phosphate, 150mM NaCl, pH: 7.2
Experiment:	SAXS data collected at EMBL P12, PETRA III on 2015 Sep 24

The F1 loop of the talin head domain acts as a gatekeeper in integrin activation and clustering. J Cell Sci 133(19) (2020)
...Liu X, Rahikainen R, Orłowski A, Jänis J, Määttä JAE, Varjosalo M, Vattulainen I, Róg T, Svergun D, Cheng RH, Wu J, Hytönen VP, Wehrle-Haller B

R_g^Guinier	3.3	nm
D_max	13.3	nm
Volume^Porod	77	nm³

SASDFT7 – Talin-1 head amino acids 1-405

Talin-1 head amino acids 1-405 Rg histogram

Sample:	Talin-1, human monomer, 51 kDa Homo sapiens protein
Buffer:	50 mM sodium phosphate, 150 mM NaCl, pH: 7.2
Experiment:	SAXS data collected at EMBL P12, PETRA III on 2015 Sep 24

R_g^Guinier	3.4	nm
D_max	11.5	nm
Volume^Porod	94	nm³

SASDFU7 – Talin-1 head amino acids 1-405(Δ134-170/GAG insert)

Talin-1 (Δ134-170/GAG insert), human experimental SAS data

Talin-1 head amino acids 1-405(Δ134-170/GAG insert) Rg histogram

Sample:	Talin-1 (Δ134-170/GAG insert), human monomer, 47 kDa Homo sapiens protein
Buffer:	50 mM sodium phosphate, 150mM NaCl, pH: 7.2
Experiment:	SAXS data collected at EMBL P12, PETRA III on 2015 Sep 24

R_g^Guinier	3.0	nm
D_max	10.2	nm
Volume^Porod	71	nm³

SASDEA8 – Full length of DnaG (DNA Primase) from Bacillus subtilis

Sample:	DNA primase monomer, 69 kDa Bacillus subtilis protein
Buffer:	25 mM Tris-HCl,100 mM NaCl, pH: 8
Experiment:	SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2018 Oct 1

Full length of DnaG primase from Bacillus subtilis
Zhongchuan Liu

R_g^Guinier	3.7	nm
D_max	14.5	nm
Volume^Porod	119	nm³

SASDKJ8 – CUB domain-containing protein 1 (CDCP1)

CUB domain-containing protein 1 experimental SAS data

CUB domain-containing protein 1 Kratky plot

Sample:	CUB domain-containing protein 1 monomer, 77 kDa Homo sapiens protein
Buffer:	10 mM phosphate, 137 mM NaCl, 2.7 mM KCl,, pH: 7.4
Experiment:	SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2020 Jul 29

Targeting a proteolytic neoepitope on CUB domain containing protein 1 (CDCP1) for RAS-driven cancers. J Clin Invest 132(4) (2022)
...Liu J, Hann B, Kossiakoff AA, Evans MJ, Leung KK, Wells JA

R_g^Guinier	4.4	nm
D_max	14.5	nm
Volume^Porod	185	nm³

SASDJK8 – N-terminal Angiopoietin-like protein 3 Hexamer

Angiopoietin-like protein 3 (N-terminal) experimental SAS data

Sample:	Angiopoietin-like protein 3 (N-terminal) hexamer, 161 kDa Homo sapiens protein
Buffer:	20 mM Tris-HCl pH 7.5, 400 mM NaCl, 2% glycerol, pH: 7.5
Experiment:	SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2019 Mar 12

Comparison of angiopoietin-like protein 3 and 4 reveals structural and mechanistic similarities. J Biol Chem :100312 (2021)
...Liu J, Neher SB

R_g^Guinier	5.6	nm
D_max	34.0	nm
Volume^Porod	380	nm³

SASDKK8 – Cleaved CUB domain containing protein 1 (CDCP1)

Cleaved - CUB domain-containing protein 1 (N-terminus)Cleaved - CUB domain-containing protein 1 (C-terminus) experimental SAS data

Cleaved - CUB domain-containing protein 1 (N-terminus) Cleaved - CUB domain-containing protein 1 (C-terminus) Kratky plot

Sample:	Cleaved - CUB domain-containing protein 1 (N-terminus) monomer, 38 kDa Homo sapiens protein Cleaved - CUB domain-containing protein 1 (C-terminus) monomer, 39 kDa Homo sapiens protein
Buffer:	10 mM phosphate, 137 mM NaCl, 2.7 mM KCl,, pH: 7.4
Experiment:	SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2020 Jul 29

Targeting a proteolytic neoepitope on CUB domain containing protein 1 (CDCP1) for RAS-driven cancers. J Clin Invest 132(4) (2022)
...Liu J, Hann B, Kossiakoff AA, Evans MJ, Leung KK, Wells JA

R_g^Guinier	4.4	nm
D_max	14.3	nm
Volume^Porod	182	nm³

SASDJL8 – N-terminal Angiopoietin-like protein 3 Trimer

Angiopoietin-related protein 3 experimental SAS data

Sample:	Angiopoietin-related protein 3 trimer, 81 kDa Homo sapiens protein
Buffer:	20 mM Tris-HCl pH 7.5, 400 mM NaCl, 2% glycerol, pH: 7.5
Experiment:	SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2019 Mar 12

Comparison of angiopoietin-like protein 3 and 4 reveals structural and mechanistic similarities. J Biol Chem :100312 (2021)
...Liu J, Neher SB

R_g^Guinier	4.6	nm
D_max	21.5	nm
Volume^Porod	71	nm³

SASDJM8 – N-terminal Angiopoietin-like protein 4 Trimer

Angiopoietin-related protein 4 experimental SAS data

Sample:	Angiopoietin-related protein 4 trimer, 46 kDa Homo sapiens protein
Buffer:	50 mM Tris-HCl pH 7.4, 300 mM NaCl, 100 mM betaine, 500 mM arginine, pH: 7.4
Experiment:	SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2017 Nov 8

Comparison of angiopoietin-like protein 3 and 4 reveals structural and mechanistic similarities. J Biol Chem :100312 (2021)
...Liu J, Neher SB

R_g^Guinier	4.7	nm
D_max	16.0	nm
Volume^Porod	69	nm³

SASDTX8 – Streptococcus pyogenes glycine cleavage system H-like protein

Glycine cleavage system H-like protein experimental SAS data

Sample:	Glycine cleavage system H-like protein monomer, 13 kDa Streptococcus pyogenes serotype … protein
Buffer:	50 mM Tris-HCl, 200 mM NaCl, 1 mM DTT, 5% (v/v) glycerol, pH: 8
Experiment:	SAXS data collected at B21, Diamond Light Source on 2016 Jul 20

Evolutionary and molecular basis of ADP-ribosylation reversal by zinc-dependent macrodomains Journal of Biological Chemistry :107770 (2024)
...Liu Q, Cowieson N, Ahel I, Filippov D, Rack J

R_g^Guinier	1.5	nm
D_max	5.0	nm
Volume^Porod	22	nm³

SASDTY8 – Streptococcus pyogenes Protein-ADP-ribose hydrolase

Protein-ADP-ribose hydrolase (D13G, Y23S, T61A, I114S, R177H, I246T) experimental SAS data

Sample:	Protein-ADP-ribose hydrolase (D13G, Y23S, T61A, I114S, R177H, I246T) monomer, 30 kDa Streptococcus pyogenes serotype … protein
Buffer:	50 mM Tris-HCl, 200 mM NaCl, 1 mM DTT, 5% (v/v) glycerol, pH: 8
Experiment:	SAXS data collected at B21, Diamond Light Source on 2016 Jul 20

Evolutionary and molecular basis of ADP-ribosylation reversal by zinc-dependent macrodomains Journal of Biological Chemistry :107770 (2024)
...Liu Q, Cowieson N, Ahel I, Filippov D, Rack J

R_g^Guinier	2.1	nm
D_max	7.3	nm
Volume^Porod	34	nm³

SASDTZ8 – Streptococcus pyogenes Protein-ADP-ribose hydrolase: glycine cleavage system H-like protein complex

Glycine cleavage system H-like proteinProtein-ADP-ribose hydrolase (D13G, Y23S, T61A, I114S, R177H, I246T) experimental SAS data

Sample:	Glycine cleavage system H-like protein monomer, 13 kDa Streptococcus pyogenes serotype … protein Protein-ADP-ribose hydrolase (D13G, Y23S, T61A, I114S, R177H, I246T) monomer, 30 kDa Streptococcus pyogenes serotype … protein
Buffer:	50 mM Tris-HCl, 200 mM NaCl, 1 mM DTT, 5% (v/v) glycerol, pH: 8
Experiment:	SAXS data collected at B21, Diamond Light Source on 2016 Jul 20

Evolutionary and molecular basis of ADP-ribosylation reversal by zinc-dependent macrodomains Journal of Biological Chemistry :107770 (2024)
...Liu Q, Cowieson N, Ahel I, Filippov D, Rack J

R_g^Guinier	2.4	nm
D_max	8.4	nm
Volume^Porod	53	nm³

SASDU39 – Nearly full-length monomeric Human Ubiquitin carboxyl-terminal hydrolase 8 (USP8) (7-1110)

Ubiquitin carboxyl-terminal hydrolase 8 experimental SAS data

Sample:	Ubiquitin carboxyl-terminal hydrolase 8 monomer, 127 kDa Homo sapiens protein
Buffer:	25 mM Tris, 150 mM NaCl, pH: 7.5
Experiment:	SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2022 Jun 18

Autoinhibition of ubiquitin-specific protease 8: insights into domain interactions and mechanisms of regulation Journal of Biological Chemistry :107727 (2024)
...Liu Y, DaDalt A, Mallare J, Fan L, Harding R, Wang Y, Vacratsis P, Huang R, Zhuang Z, Tong Y

R_g^Guinier	8.4	nm
D_max	31.8	nm
Volume^Porod	327	nm³

SASDEP9 – Cyclic GMP-AMP synthase (cGAS)

Cyclic GMP-AMP synthase experimental SAS data

Cyclic GMP-AMP synthase (cGAS) Rg histogram

Sample:	Cyclic GMP-AMP synthase monomer, 61 kDa Homo sapiens protein
Buffer:	20 mM HEPES, pH: 7.4
Experiment:	SAXS data collected at EMBL P12, PETRA III on 2017 Apr 25

cGAS facilitates sensing of extracellular cyclic dinucleotides to activate innate immunity. EMBO Rep (2019)
Liu H, Moura-Alves P, Pei G, Mollenkopf HJ, Hurwitz R, Wu X, Wang F, Liu S, Ma M, Fei Y, Zhu C, Koehler AB, Oberbeck-Mueller D, Hahnke K, Klemm M, Guhlich-Bornhof U, Ge B, Tuukkanen A, Kolbe M, Dorhoi...

R_g^Guinier	3.1	nm
D_max	12.7	nm
Volume^Porod	110	nm³

SASDEQ9 – Cyclic GMP-AMP synthase (cGAS) with cyclic guanosine monophosphate–adenosine monophosphate (2'3'-cGAMP)

Cyclic GMP-AMP synthase2'-O,5'-O-((adenosine-3'-O,5'-O-diyl)bisphosphinico)guanosine experimental SAS data

Cyclic GMP-AMP synthase (cGAS) with cyclic guanosine monophosphate–adenosine monophosphate (2'3'-cGAMP) Rg histogram

Sample:	Cyclic GMP-AMP synthase dimer, 123 kDa Homo sapiens protein 2'-O,5'-O-((adenosine-3'-O,5'-O-diyl)bisphosphinico)guanosine dimer, 1 kDa
Buffer:	20 mM HEPES, pH: 7.4
Experiment:	SAXS data collected at EMBL P12, PETRA III on 2017 Apr 25

R_g^Guinier	3.9	nm
D_max	14.1	nm
Volume^Porod	127	nm³

SASDQV9 – Nanobody1 in complex with the extracellular domain of human BCMA

Tumor necrosis factor receptor superfamily member 17Nanobody1 experimental SAS data

Tumor necrosis factor receptor superfamily member 17 Nanobody1 Kratky plot

Sample:	Tumor necrosis factor receptor superfamily member 17 monomer, 6 kDa Homo sapiens protein Nanobody1 monomer, 14 kDa protein
Buffer:	20 mM Tris, 100 mM NaCl, pH: 8
Experiment:	SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2022 Aug 28

Antigen-induced chimeric antigen receptor multimerization amplifies on-tumor cytotoxicity. Signal Transduct Target Ther 8(1):445 (2023)
...Liu KW, Li N, Cui JC, Huang GX, Liu CL, Xu J, Mi JQ, Chen Z, Fan XH, Chen SJ, Chen S

R_g^Guinier	3.0	nm
D_max	9.8	nm
Volume^Porod	52	nm³

SASDQW9 – Nanobody2 in complex with the extracellular domain of human BCMA

Tumor necrosis factor receptor superfamily member 17Nanobody2 experimental SAS data

Tumor necrosis factor receptor superfamily member 17 Nanobody2 Kratky plot

Sample:	Tumor necrosis factor receptor superfamily member 17 monomer, 6 kDa Homo sapiens protein Nanobody2 monomer, 14 kDa protein
Buffer:	20 mM Tris, 100 mM NaCl, pH: 8
Experiment:	SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2022 Aug 28

R_g^Guinier	2.0	nm
D_max	9.0	nm
Volume^Porod	24	nm³

SASDQX9 – Tandem nanobody in complex with the extracellular domain of human BCMA

Tumor necrosis factor receptor superfamily member 17Tandem nanobody experimental SAS data

Tumor necrosis factor receptor superfamily member 17 Tandem nanobody Kratky plot

Sample:	Tumor necrosis factor receptor superfamily member 17 monomer, 6 kDa Homo sapiens protein Tandem nanobody monomer, 27 kDa protein
Buffer:	20 mM Tris, 100 mM NaCl, pH: 8
Experiment:	SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2022 Aug 28

R_g^Guinier	5.1	nm
D_max	23.3	nm
Volume^Porod	247	nm³

SASDM47 – NAD glycohydrolase (NADase)

NAD glycohydrolase experimental SAS data

Sample:	NAD glycohydrolase monomer, 47 kDa Streptococcus pyogenes M1 … protein
Buffer:	phosphate buffered saline, pH: 7.4
Experiment:	SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2018 Oct 16

Structural basis underlying the synergism of NADase and SLO during group A Streptococcus infection. Commun Biol 6(1):124 (2023)
...Liu CC, Senda T, Wang S

R_g^Guinier	3.0	nm
D_max	103.0	nm
Volume^Porod	66	nm³

SASDA49 – Cation-free slp-B53

Sample:	S-layer protein monomer, 116 kDa Lysinibacillus sphaericus protein
Buffer:	Water, pH: 7
Experiment:	SAXS data collected at EMBL P12, PETRA III on 2015 Jun 2

Analysis of self-assembly of S-layer protein slp-B53 from Lysinibacillus sphaericus. Eur Biophys J 46(1):77-89 (2017)
Liu J, Falke S, Drobot B, Oberthuer D, Kikhney A, Guenther T, Fahmy K, Svergun D, Betzel C, Raff J

R_g^Guinier	5.8	nm
D_max	22.0	nm
Volume^Porod	495	nm³

SASDLD9 – 2-aminomuconic 6-semialdehyde dehydrogenase wild-type

2-aminomuconic 6-semialdehyde dehydrogenase experimental SAS data

Sample:	2-aminomuconic 6-semialdehyde dehydrogenase tetramer, 215 kDa Pseudomonas sp. protein
Buffer:	20 mM HEPES, 150 mM NaCl, pH: 7
Experiment:	SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2021 Feb 1

The tetrameric assembly of 2-aminomuconic 6-semialdehyde dehydrogenase is a functional requirement of cofactor NAD(+) binding. Environ Microbiol 24(7):2994-3012 (2022)
...Liu G, Su D

R_g^Guinier	3.9	nm
D_max	11.6	nm
Volume^Porod	326	nm³

SASDM57 – NAD glycohydrolase (NADase)/Streptolysin O (SLO) complex (SAXS with additional contrast variation SANS data)

NAD glycohydrolaseStreptolysin O (T66M) experimental SAS data

Sample:	NAD glycohydrolase monomer, 47 kDa Streptococcus pyogenes M1 … protein Streptolysin O (T66M) monomer, 63 kDa Streptococcus pyogenes serotype … protein
Buffer:	phosphate buffered saline, pH: 7.4
Experiment:	SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2018 Oct 16

Structural basis underlying the synergism of NADase and SLO during group A Streptococcus infection. Commun Biol 6(1):124 (2023)
...Liu CC, Senda T, Wang S

R_g^Guinier	4.8	nm
D_max	18.4	nm
Volume^Porod	125	nm³

SASDA59 – slp-B53 with Ca2+

Sample:	S-layer protein monomer, 116 kDa Lysinibacillus sphaericus protein
Buffer:	Water with Ca2+, pH:
Experiment:	SAXS data collected at EMBL P12, PETRA III on 2015 Jun 2

R_g^Guinier	6.4	nm
D_max	28.1	nm
Volume^Porod	609	nm³

SASDLC9 – 2-aminomuconic 6-semialdehyde dehydrogenase double truncation mutant (Δ124-138; Δ477-491)

Sample:	2-aminomuconic 6-semialdehyde dehydrogenase dimer, 101 kDa Pseudomonas sp. protein
Buffer:	20 mM HEPES, 150 mM NaCl, pH: 7
Experiment:	SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2021 Feb 1

The tetrameric assembly of 2-aminomuconic 6-semialdehyde dehydrogenase is a functional requirement of cofactor NAD(+) binding. Environ Microbiol 24(7):2994-3012 (2022)
...Liu G, Su D

R_g^Guinier	2.9	nm
D_max	9.0	nm
Volume^Porod	117	nm³

SASDA69 – slp-B53 with Mg2+

Sample:	S-layer protein monomer, 116 kDa Lysinibacillus sphaericus protein
Buffer:	Water with Mg2+, pH:
Experiment:	SAXS data collected at EMBL P12, PETRA III on 2015 Jun 2

R_g^Guinier	6.6	nm
D_max	29.0	nm
Volume^Porod	597	nm³

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